Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Agu Pert"'
Publikováno v:
Neuroscience. 115:67-78
Pharmacological manipulation of both dopamine and glutamate systems affects motor responses in laboratory animals. The two systems, however, seem to act in opposite ways, since direct or indirect activation of dopamine receptors induces similar stimu
Publikováno v:
Pharmacology Biochemistry and Behavior. 69:519-526
The effects of the indirect dopamine (DA) agonists cocaine and D-amphetamine on locomotor activity were examined in Fawn hooded (FH) rats and Wistar rats. The effect of isolation rearing was also examined to determine if it might have different effec
Publikováno v:
Synapse. 33:16-25
Effects of i.c.v. administration of 5,7-dihydroxytryptamine (5,7-DHT) on biochemistry and behavior were studied in awake Sprague-Dawley rats. It was found that 5,7-DHT depletion of striatal tissue levels of serotonin (5-HT) does not diminish extracel
Publikováno v:
Psychopharmacology. 139:210-216
These experiments examined the hypothesis that isolation-rearing and strain influence hedonic mechanisms. In experiment 1, voluntary consumption of ethanol and water was monitored in the home cage of Fawn Hooded (FH) and Wistar rats. FH rats were fou
Publikováno v:
Psychopharmacology. 139:203-209
Voluntary ethanol (EtOH) consumption is increased by isolation-rearing in several rat strains. The following experiments examined the effects of isolation-rearing on basal and ethanol-stimulated behavior in Fawn Hooded rats, an alcohol-preferring rat
Publikováno v:
Brain Research. 786:39-46
Elevated blood concentrations of corticosterone (CORT), an adrenal steroid associated with stress responses, is one of the endocrine correlates of cocaine treatment. Experiment 1 confirmed and extended previous findings that chronic cocaine treatment
Publikováno v:
Psychopharmacology. 135:107-118
Phencyclidine (PCP) and phencyclidine-like drugs (TCP, dexoxadrol, MK-801, and SKF 10,047) were evaluated for their ability to induce rotational behavior in rats with unilateral 6-OHDA lesions of the medial forebrain bundle and for their ability to a
Autor:
Richard B. Rothman, Agu Pert
Publikováno v:
Pharmacology Biochemistry and Behavior. 49:399-404
The purpose of these studies was to determine if ECS is capable of preventing the retention of cocaine-induced conditioned increases in locomotor behavior. One group of rats (paired) was injected with 40 mg/kg of cocaine immediately before a 30 min e
Publikováno v:
Brain Research. 629:31-39
Stimuli associated with cocaine come to acquire incentive-motivational as well as secondary reinforcing properties which can energize and maintain behavior in laboratory animals as well as precipitate craving in addicts. Environmental stimuli paired
Autor:
Alessandro Zocchi, Agu Pert
Publikováno v:
Brain Research. 627:186-192
It has been proposed by some that the D1 receptor effects are mediated through striatal actions while others have suggested that they are determined indirectly through the frontal cortex. The experiments reported here represent a further attempt to r