Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Agota Apati"'
Autor:
Léa Broca-Brisson, Rania Harati, Clémence Disdier, Orsolya Mozner, Romane Gaston-Breton, Auriane Maïza, Narciso Costa, Anne-Cécile Guyot, Balazs Sarkadi, Agota Apati, Matthew R Skelton, Lucie Madrange, Frank Yates, Jean Armengaud, Rifat Hamoudi, Aloïse Mabondzo
Publikováno v:
eLife, Vol 12 (2023)
Creatine transporter deficiency (CTD) is an X-linked disease caused by mutations in the SLC6A8 gene. The impaired creatine uptake in the brain results in intellectual disability, behavioral disorders, language delay, and seizures. In this work, we ge
Externí odkaz:
https://doaj.org/article/e52897c931c1438dbf89ad9807783b44
Autor:
Szilárd Tóth, Márton F. Szlávik, Réka Mandel, Fanni Fekecs, Gábor Tusnády, Flóra Vajda, Nóra Varga, Ágota Apáti, Attila Bényei, Attila Paczal, András Kotschy, Gergely Szakács
Publikováno v:
ACS Omega, Vol 9, Iss 29, Pp 32226-32234 (2024)
Externí odkaz:
https://doaj.org/article/79a1802ae16c4eafaec39a09939a8c03
Autor:
Bálint Jezsó, Sára Kálmán, Kiara Gitta Farkas, Edit Hathy, Katalin Vincze, Dzsenifer Kovács-Schoblocher, Julianna Lilienberg, Csongor Tordai, Zsófia Nemoda, László Homolya, Ágota Apáti, János M. Réthelyi
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 688 (2024)
Background: Induced pluripotent stem cell (iPSC) based neuronal differentiation is valuable for studying neuropsychiatric disorders and pharmacological mechanisms at the cellular level. We aimed to examine the effects of typical and atypical antipsyc
Externí odkaz:
https://doaj.org/article/3e981b6cc32b43c692ca79eacd6a001e
Autor:
Gergely Attila Rácz, Nikolett Nagy, György Várady, József Tóvári, Ágota Apáti, Beáta G. Vértessy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract In human cells two dUTPase isoforms have been described: one nuclear (DUT-N) and one mitochondrial (DUT-M), with cognate localization signals. In contrast, here we identified two additional isoforms; DUT-3 without any localization signal and
Externí odkaz:
https://doaj.org/article/3c62db1bbec842f69dc1d409652a918e
Publikováno v:
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. 18(4)
Over the past decade we witnessed the birth of a new scientific area that lies at the borders of developmental biology, stem cell biology, basic and clinical neuroscience. In vitro disease modeling refers to the approach that exploits the capacity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::282698dc483d103c246c29b94da1d91f
https://pubmed.ncbi.nlm.nih.gov/28259862
https://pubmed.ncbi.nlm.nih.gov/28259862
Autor:
Tünde Berecz, Angela Yiu, Orsolya Vittay, Barbara Orsolits, Maxime Mioulane, Cristobal G. dosRemedios, Robin Ketteler, Bela Merkely, Ágota Apáti, Sian E. Harding, Nicola Hellen, Gabor Foldes
Publikováno v:
ESC Heart Failure, Vol 9, Iss 1, Pp 224-235 (2022)
Abstract Aims Hippo signalling is an evolutionarily conserved pathway that controls organ size by regulating apoptosis, cell proliferation, and stem cell self‐renewal. Recently, the pathway has been shown to exert powerful growth regulatory activit
Externí odkaz:
https://doaj.org/article/cfa42de32b8a4c7f89de595f9ce54f50
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Reverse transcription—quantitative real-time PCR (RT-qPCR) is a ubiquitously used method in biological research, however, finding appropriate reference genes for normalization is challenging. We aimed to identify genes characterized with l
Externí odkaz:
https://doaj.org/article/75fd21e5bc2547d4bfcc35d5f61d861c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Microglia, the primary immune cells of the brain, significantly influence the fate of neurons after neural damage. Depending on the local environment, they exhibit a wide range of phenotypes, including patrolling (naïve), proinflammatory, and anti-i
Externí odkaz:
https://doaj.org/article/51edf91c7d484bc58a643f06f51bab9f
Autor:
Edit Hathy, Eszter Szabó, Nóra Varga, Zsuzsa Erdei, Csongor Tordai, Boróka Czehlár, Máté Baradits, Bálint Jezsó, Júlia Koller, László Nagy, Mária Judit Molnár, László Homolya, Zsófia Nemoda, Ágota Apáti, János M. Réthelyi
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background De novo mutations (DNMs) have been implicated in the etiology of schizophrenia (SZ), a chronic debilitating psychiatric disorder characterized by hallucinations, delusions, cognitive dysfunction, and decreased community functionin
Externí odkaz:
https://doaj.org/article/0aa0cb71e7ad4e1da3db707edcd65bb5
Autor:
Julianna Lilienberg, Zoltán Hegyi, Eszter Szabó, Edit Hathy, András Málnási-Csizmadia, János M. Réthelyi, Ágota Apáti, László Homolya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Studies on neural development and neuronal regeneration after injury are mainly based on animal models. The establishment of pluripotent stem cell (PSC) technology, however, opened new perspectives for better understanding these processes in human mo
Externí odkaz:
https://doaj.org/article/907711e1ead44d3db302466c145f87d3