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Akademický článek

Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of neonatal mice

Autor: Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Ágota Ádám, András Csillag

Publikováno v: Frontiers in Neuroanatomy, Vol 18 (2024)

Gestational exposure to valproic acid (VPA) is a valid rodent model of human autism spectrum disorder (ASD). VPA treatment is known to bring about specific behavioral deficits of sociability, matching similar alterations in human autism. Previous qua

Externí odkaz: https://doaj.org/article/5441ba83c243421d93fdb7a8d2df8345

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Akademický článek

Early cellular and synaptic changes in dopaminoceptive forebrain regions of juvenile mice following gestational exposure to valproate

Autor: Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Sophie Holtkamp, Diego Echevarría, István Adorján, Ágota Ádám, András Csillag

Publikováno v: Frontiers in Neuroanatomy, Vol 17 (2023)

Gestational exposure of mice to valproic acid (VPA) is one currently used experimental model for the investigation of typical failure symptoms associated with autism spectrum disorder (ASD). In the present study we hypothesized that the reduction of

Externí odkaz: https://doaj.org/article/df3125b640be44f48ff777645729a159

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Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens

Autor: Balapal S. Basavarajappa, Agota Adam, Basalingappa L. Hungund, Istvan Szakall, Csaba Vadasz

Publikováno v: Journal of Neurochemistry. 84:698-704

The mechanisms underlying predisposition to alcohol abuse and alcoholism are poorly understood. In this study, we evaluated the role of cannabinoid (CB1) receptors in (i) voluntary alcohol consumption, and (ii) acute alcohol-induced dopamine (DA) rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4589098bf6f827e204672bffa2a947e4
https://doi.org/10.1046/j.1471-4159.2003.01576.x

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Akademický článek

Avian models for brain mechanisms underlying altered social behavior in autism

Autor: András Csillag, Ágota Ádám, Gergely Zachar

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

The current review is an update on experimental approaches in which birds serve as model species for the investigation of typical failure symptoms associated with autism spectrum disorder (ASD). The discussion is focused on deficiencies of social beh

Externí odkaz: https://doaj.org/article/584d463f2452438998d2e0edc95600ff

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Akademický článek

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Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens

Autor: Basalingappa L, Hungund, Istvan, Szakall, Agota, Adam, Balapal S, Basavarajappa, Csaba, Vadasz

Publikováno v: Journal of neurochemistry. 84(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::666304d8726fa842590f20fe3fd5be20
https://pubmed.ncbi.nlm.nih.gov/12562514

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Akademický článek

Gestational Exposure to Sodium Valproate Disrupts Fasciculation of the Mesotelencephalic Dopaminergic Tract, With a Selective Reduction of Dopaminergic Output From the Ventral Tegmental Area

Autor: Ágota Ádám, Róbert Kemecsei, Verónica Company, Raquel Murcia-Ramón, Iris Juarez, László I. Gerecsei, Gergely Zachar, Diego Echevarría, Eduardo Puelles, Salvador Martínez, András Csillag

Publikováno v: Frontiers in Neuroanatomy, Vol 14 (2020)

Gestational exposure to valproic acid (VPA) is known to cause behavioral deficits of sociability, matching similar alterations in human autism spectrum disorder (ASD). Available data are scarce on the neuromorphological changes in VPA-exposed animals

Externí odkaz: https://doaj.org/article/934517db06d1472986fd74f4e9be40b6

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Akademický článek

Valproate Exposure in ovo Attenuates the Acquisition of Social Preferences of Young Post-hatch Domestic Chicks

Autor: Gergely Zachar, András S. Tóth, László I. Gerecsei, Sándor Zsebők, Ágota Ádám, András Csillag

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

Embryonic exposure to valproic acid (VPA) is known to produce sociability deficits, resembling human autistic phenotypes, in several vertebrate species. Animals living in groups prefer the proximity of peers and have the ability to perceive and to re

Externí odkaz: https://doaj.org/article/8bdc1b4f32b14b4f81added71b5b3a4d

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Akademický článek

Gestational Exposure to the Synthetic Cathinone Methylenedioxypyrovalerone Results in Reduced Maternal Care and Behavioral Alterations in Mouse Pups

Autor: László I. Gerecsei, András Csillag, Gergely Zachar, Lőrinc Gévai, László Simon, Árpád Dobolyi, Ágota Ádám

Publikováno v: Frontiers in Neuroscience, Vol 12 (2018)

The member of synthetic cathinone family, methylenedioxypyrovalerone (MDPV), is a frequently used psychoactive drug of abuse. The objective of our study was to determine the effect of MDPV (administered from the 8th to the 14th day of gestation) on t

Externí odkaz: https://doaj.org/article/00e4a69f134a41dd91c079c08632da4c

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