Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Agostino Palmeri"'
Autor:
Sebastiano Alfio Torrisi, Federica Geraci, Maria Rosaria Tropea, Margherita Grasso, Giuseppe Caruso, Annamaria Fidilio, Nicolò Musso, Giulia Sanfilippo, Fabio Tascedda, Agostino Palmeri, Salvatore Salomone, Filippo Drago, Daniela Puzzo, Gian Marco Leggio, Filippo Caraci
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Depression is a risk factor for the development of Alzheimer’s disease (AD), and the presence of depressive symptoms significantly increases the conversion of mild cognitive impairment (MCI) into AD. A long-term treatment with antidepressants reduc
Externí odkaz:
https://doaj.org/article/7228b81793494c7c8ea808a620659ae9
Autor:
Daniela Puzzo, Roberto Piacentini, Mauro Fá, Walter Gulisano, Domenica D Li Puma, Agnes Staniszewski, Hong Zhang, Maria Rosaria Tropea, Sara Cocco, Agostino Palmeri, Paul Fraser, Luciano D'Adamio, Claudio Grassi, Ottavio Arancio
Publikováno v:
eLife, Vol 6 (2017)
The concurrent application of subtoxic doses of soluble oligomeric forms of human amyloid-beta (oAβ) and Tau (oTau) proteins impairs memory and its electrophysiological surrogate long-term potentiation (LTP), effects that may be mediated by intra-ne
Externí odkaz:
https://doaj.org/article/09a1c7b338a4448f8aa2a037b888cd9f
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 2, Pp 371-387 (2008)
Daniela Puzzo1,2, Salvatore Sapienza1, Ottavio Arancio2, Agostino Palmeri11Dept of Physiological Sciences, University of Catania, Catania, Italy; 2Dept of Pathology, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia U
Externí odkaz:
https://doaj.org/article/c8e2691e7a18446dbaf233fd15c69b3b
Autor:
Maria Rosaria Tropea, Walter Gulisano, Valeria Vacanti, Ottavio Arancio, Daniela Puzzo, Agostino Palmeri
Publikováno v:
Free Radical Biology and Medicine. 193:657-668
The nitric oxide (NO)/cGMP pathway has been extensively studied for its pivotal role in synaptic plasticity and memory processes, resulting in an increase of cAMP response element-binding (CREB) phosphorylation, and consequent synthesis of plasticity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3104dcfeebb1858d5e872ea81de8ffdd
https://doi.org/10.1016/j.freeradbiomed.2022.11.022
https://doi.org/10.1016/j.freeradbiomed.2022.11.022
Autor:
Marcello Melone, Walter Gulisano, Domenica Donatella Li Puma, Daniela Puzzo, Ottavio Arancio, Claudio Grassi, Fiorenzo Conti, Maria Rosaria Tropea, Agostino Palmeri
Publikováno v:
Neurobiol Aging
The increase of oligomeric amyloid-beta (oAβ) has been related to synaptic dysfunction, thought to be the earliest event in Alzheimer's disease pathophysiology. Conversely, the suppression of endogenous Aβ impaired synaptic plasticity and memory, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77cc70b7d100dbdd06015acf446e361
https://doi.org/10.1016/j.neurobiolaging.2018.06.025
https://doi.org/10.1016/j.neurobiolaging.2018.06.025
Autor:
Walter Gulisano, Elisa Calcagno, Ernesto Fedele, Maria Rosaria Tropea, Ottavio Arancio, Claudia Rebosio, Roberta Ricciarelli, Maria Adelaide Pronzato, Utpal Das, Subhojit Roy, Silvia Conti, Daniela Puzzo, Agostino Palmeri, Daniela Rivera
Publikováno v:
The Journal of Neuroscience. 37:6926-6937
High levels of amyloid-β peptide (Aβ) have been related to Alzheimer9s disease pathogenesis. However, in the healthy brain, low physiologically relevant concentrations of Aβ are necessary for long-term potentiation (LTP) and memory. Because cGMP p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c4ea990f295e0c80b6371ab386e78b
https://doi.org/10.1523/jneurosci.3607-16.2017
https://doi.org/10.1523/jneurosci.3607-16.2017
Publikováno v:
Molecular and Cellular Neuroscience. 81:64-71
Cell adhesion molecules (CAMs) have a pivotal role in building and maintaining synaptic structures during brain development participating in axonal elongation and pathfinding, glial guidance of neuronal migration, as well as myelination. CAMs express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9f3f5991a8e44fea440116df56c3e4
https://doi.org/10.1016/j.mcn.2016.12.003
https://doi.org/10.1016/j.mcn.2016.12.003
Autor:
Claudio Grassi, Salvatore Giunta, Agostino Palmeri, Nicola Origlia, Fiorenzo Conti, Maria Rosaria Tropea, Cristian Ripoli, Marcello Melone, Domenica Donatella Li Puma, Walter Gulisano, Ottavio Arancio, Daniele Marcotulli, Daniela Puzzo, Sara Cocco
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(30)
Failure of anti-amyloid-β peptide (Aβ) therapies against Alzheimer's disease (AD), a neurodegenerative disorder characterized by high amounts of the peptide in the brain, raised the question of the physiological role of Aβ released at low concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b7fa317942b4fe2a71ea8a6ab1bc1c
https://pubmed.ncbi.nlm.nih.gov/31127002
https://pubmed.ncbi.nlm.nih.gov/31127002
Publikováno v:
Neuropharmacology. 138
Cyclic nucleotides cAMP and cGMP cooperate to ensure memory acquisition and consolidation. Increasing their levels by phosphodiesterase inhibitors (PDE-Is) enhanced cognitive functions and rescued memory loss in different models of aging and Alzheime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c126099b266d578b704acbb703f40581
https://pubmed.ncbi.nlm.nih.gov/29885420
https://pubmed.ncbi.nlm.nih.gov/29885420
Autor:
Devangere P. Devanand, A. Amato, Luciano D'Adamio, Ottavio Arancio, Walter Gulisano, Mauro Fa, Lawrence S. Honig, Marian A Baltrons, Agostino Palmeri, Daniela Puzzo, Daniele Maugeri, Claudio Grassi
Publikováno v:
J Alzheimers Dis
The "Amyloid Cascade Hypothesis" has dominated the Alzheimer's disease (AD) field in the last 25 years. It posits that the increase of amyloid-β (Aβ) is the key event in AD that triggers tau pathology followed by neuronal death and eventually, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20b22c7f073c6d25d839d224dfe3593
http://hdl.handle.net/10807/128648
http://hdl.handle.net/10807/128648
