Zobrazeno 1 - 10
of 532
pro vyhledávání: '"Agostino Bruno"'
Autor:
Michael J. Hurley, Claudio Urra, B. Maximiliano Garduno, Agostino Bruno, Allison Kimbell, Brent Wilkinson, Cristina Marino-Buslje, Marcelo Ezquer, Fernando Ezquer, Pedro F. Aburto, Elie Poulin, Rodrigo A. Vasquez, Robert Deacon, Ariel Avila, Francisco Altimiras, Peter Whitney Vanderklish, Guido Zampieri, Claudio Angione, Gabriele Constantino, Todd C. Holmes, Marcelo P. Coba, Xiangmin Xu, Patricia Cogram
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
The degu (Octodon degus) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age some degu, but not all individuals, develop cognitive decline and brain pathology
Externí odkaz:
https://doaj.org/article/e09a35f5fb5646e3af0bc630bdc8e841
Autor:
Filippo Pigazzani, Davide Gorni, Kenneth A. Dyar, Matteo Pedrelli, Gwen Kennedy, Gabriele Costantino, Agostino Bruno, Isla Mackenzie, Thomas M. MacDonald, Uwe J. F. Tietge, Jacob George
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1541 (2022)
Oxidative stress participates in the development and exacerbation of cardiovascular diseases (CVD). The ability to promptly quantify an imbalance in an individual reductive-oxidative (RedOx) state could improve cardiovascular risk assessment and mana
Externí odkaz:
https://doaj.org/article/a0accbb73966423d96c1fc83daa20d07
Autor:
Giannamaria Annunziato, Costanza Spadini, Marialaura Marchetti, Nina Franko, Marialaura Pavone, Mattia Iannarelli, Agostino Bruno, Marco Pieroni, Stefano Bettati, Clotilde Silvia Cabassi, Barbara Campanini, Gabriele Costantino
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 766 (2022)
Antibacterial adjuvants are of great significance, since they allow one to downscale the therapeutic dose of conventional antibiotics and reduce the insurgence of antibacterial resistance. Herein, we report that O-acetylserine sulfhydrylase (OASS) in
Externí odkaz:
https://doaj.org/article/a4c0d428c9844ac3b8d2f6512eb7e7a4
Autor:
Daniele Di Marino, Agostino Bruno, Manuela Grimaldi, Mario Scrima, Ilaria Stillitano, Giuseppina Amodio, Grazia Della Sala, Alice Romagnoli, Augusta De Santis, Ornella Moltedo, Paolo Remondelli, Giovanni Boccia, Gerardino D'Errico, Anna Maria D'Ursi, Vittorio Limongelli
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Gp36 is the virus envelope glycoproteins catalyzing the fusion of the feline immunodeficiency virus with the host cells. The peptide C8 is a tryptophan-rich peptide corresponding to the fragment 770W-I777 of gp36 exerting antiviral activity by bindin
Externí odkaz:
https://doaj.org/article/c7ebdf29513a4dbf81914ba94e207409
Autor:
Gaia Faustini, Francesca Longhena, Agostino Bruno, Federica Bono, Jessica Grigoletto, Luca La Via, Alessandro Barbon, Andrea Casiraghi, Valentina Straniero, Ermanno Valoti, Gabriele Costantino, Fabio Benfenati, Cristina Missale, Marina Pizzi, Maria Grazia Spillantini, Arianna Bellucci
Publikováno v:
Neurobiology of Disease, Vol 138, Iss , Pp 104789- (2020)
Loss of dopaminergic nigrostriatal neurons and fibrillary α-synuclein (α-syn) aggregation in Lewy bodies (LB) characterize Parkinson's disease (PD). We recently found that Synapsin III (Syn III), a phosphoprotein regulating dopamine (DA) release wi
Externí odkaz:
https://doaj.org/article/62b2da3107734573927f1feedb3da04f
Autor:
Joana Magalhães, Nina Franko, Giannamaria Annunziato, Martin Welch, Stephen K. Dolan, Agostino Bruno, Andrea Mozzarelli, Stefano Armao, Aigars Jirgensons, Marco Pieroni, Gabriele Costantino, Barbara Campanini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1444-1452 (2018)
Several bacteria rely on the reductive sulphur assimilation pathway, absent in mammals, to synthesise cysteine. Reduction of virulence and decrease in antibiotic resistance have already been associated with mutations on the genes that codify cysteine
Externí odkaz:
https://doaj.org/article/30e250b250a64c3580f2300940788456
Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases
Autor:
Giannamaria Annunziato, Laura Giovati, Andrea Angeli, Marialaura Pavone, Sonia Del Prete, Marco Pieroni, Clemente Capasso, Agostino Bruno, Stefania Conti, Walter Magliani, Claudiu T. Supuran, Gabriele Costantino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1537-1544 (2018)
Infections caused by pathogens resistant to the available antimicrobial treatments represent nowadays a threat to global public health. Recently, it has been demonstrated that carbonic anhydrases (CAs) are essential for the growth of many pathogens a
Externí odkaz:
https://doaj.org/article/866c6fb23b9740298ef45e53988bde41
Autor:
Andrea Sartori, Kelly Bugatti, Elisabetta Portioli, Monica Baiula, Irene Casamassima, Agostino Bruno, Francesca Bianchini, Claudio Curti, Franca Zanardi, Lucia Battistini
Publikováno v:
Molecules, Vol 26, Iss 19, p 6066 (2021)
Integrin α4β1 belongs to the leukocyte integrin family and represents a therapeutic target of relevant interest given its primary role in mediating inflammation, autoimmune pathologies and cancer-related diseases. The focus of the present work is t
Externí odkaz:
https://doaj.org/article/166aa7c11f0a4b829f71def7b9ba5c9c
Autor:
Mirco Dindo, Egidia Costanzi, Marco Pieroni, Claudio Costantini, Giannamaria Annunziato, Agostino Bruno, Nancy P. Keller, Luigina Romani, Teresa Zelante, Barbara Cellini
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
The rise in the frequency of nosocomial infections is becoming a major problem for public health, in particular in immunocompromised patients. Aspergillus fumigatus is an opportunistic fungus normally present in the environment directly responsible f
Externí odkaz:
https://doaj.org/article/ccf12ae7da1948afab49db974d7bf608
Autor:
Joana Magalhães, Nina Franko, Samanta Raboni, Giannamaria Annunziato, Päivi Tammela, Agostino Bruno, Stefano Bettati, Stefano Armao, Costanza Spadini, Clotilde Silvia Cabassi, Andrea Mozzarelli, Marco Pieroni, Barbara Campanini, Gabriele Costantino
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 174 (2021)
Many bacteria and actinomycetales use L-cysteine biosynthesis to increase their tolerance to antibacterial treatment and establish a long-lasting infection. In turn, this might lead to the onset of antimicrobial resistance that currently represents o
Externí odkaz:
https://doaj.org/article/f1d7405d6d5a4d12aad19e9550530af9