Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Ago R"'
Autor:
Mart Ernits, Olavi Reinsalu, Naresh Yandrapalli, Sergei Kopanchuk, Ehsan Moradpur-Tari, Immanuel Sanka, Ott Scheler, Ago Rinken, Reet Kurg, Andreas Kyritsakis, Veikko Linko, Veronika Zadin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract In advanced drug delivery, versatile liposomal formulations are commonly employed for safer and more accurate therapies. Here we report a method that allows a straightforward production of synthetic monodisperse (~ 100 μm) giant unilamellar
Externí odkaz:
https://doaj.org/article/d3722b7656734c66a34061ea096fff76
Akademický článek
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Akademický článek
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Autor:
Jurgita Matulienė, Gediminas Žvinys, Vytautas Petrauskas, Agnė Kvietkauskaitė, Audrius Zakšauskas, Kirill Shubin, Asta Zubrienė, Lina Baranauskienė, Lina Kačenauskaitė, Sergei Kopanchuk, Santa Veiksina, Vaida Paketurytė-Latvė, Joana Smirnovienė, Vaida Juozapaitienė, Aurelija Mickevičiūtė, Vilma Michailovienė, Jelena Jachno, Dovilė Stravinskienė, Aistė Sližienė, Agnė Petrošiūtė, Holger M. Becker, Justina Kazokaitė-Adomaitienė, Ala Yaromina, Edita Čapkauskaitė, Ago Rinken, Virginija Dudutienė, Ludwig J Dubois, Daumantas Matulis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-25 (2022)
Abstract Numerous human cancers, especially hypoxic solid tumors, express carbonic anhydrase IX (CAIX), a transmembrane protein with its catalytic domain located in the extracellular space. CAIX acidifies the tumor microenvironment, promotes metastas
Externí odkaz:
https://doaj.org/article/37ebb5e55c0a4123a7c8f686b66ab087
Autor:
Mohammed A. S. Ali, Kaspar Hollo, Tõnis Laasfeld, Jane Torp, Maris-Johanna Tahk, Ago Rinken, Kaupo Palo, Leopold Parts, Dmytro Fishman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Brightfield cell microscopy is a foundational tool in life sciences. The acquired images are prone to contain visual artifacts that hinder downstream analysis, and automatically removing them is therefore of great practical interest. Deep co
Externí odkaz:
https://doaj.org/article/7be180ec8d054da98d2d78766b4197a4
Autor:
Maris-Johanna Tahk, Tõnis Laasfeld, Elo Meriste, Jose Brea, Maria Isabel Loza, Maria Majellaro, Marialessandra Contino, Eddy Sotelo, Ago Rinken
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Dopamine receptors are G-protein-coupled receptors that are connected to severe neurological disorders. The development of new ligands targeting these receptors enables gaining a deeper insight into the receptor functioning, including binding mechani
Externí odkaz:
https://doaj.org/article/22db54a4222f4329a1d283cd834504c0
Autor:
Masuma Khatun, Alvin Meltsov, Darja Lavogina, Marina Loid, Keiu Kask, Riikka K. Arffman, Henna-Riikka Rossi, Freddy Lättekivi, Kersti Jääger, Kaarel Krjutškov, Ago Rinken, Andres Salumets, Terhi T. Piltonen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Hyperandrogenic women with PCOS show disrupted decidualization (DE) and placentation. Dihydrotestosterone (DHT) is reported to enhance DE in non-PCOS endometrial stromal cells (eSCCtrl); however, this has not been assessed in PCOS cells (eSC
Externí odkaz:
https://doaj.org/article/9dcc0bb266634d95ab67b30d78611c06
Autor:
Darja Lavogina, Nadja Visser, Külli Samuel, Eva Davey, Richelle D. Björvang, Jasmin Hassan, Jani Koponen, Panu Rantakokko, Hannu Kiviranta, Ago Rinken, Matts Olovsson, Andres Salumets, Pauliina Damdimopoulou
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Multiple studies have shown associations between exposure to endocrine disrupting chemicals (EDCs) and reduced fertility in women. However, little is known about the target organs of chemical disruption of female fertility. Here, we focus on the horm
Externí odkaz:
https://doaj.org/article/da01ba73769e4384a659109a72a1b634
Autor:
Maris-Johanna Tahk, Jane Torp, Mohammed A. S. Ali, Dmytro Fishman, Leopold Parts, Lukas Grätz, Christoph Müller, Max Keller, Santa Veiksina, Tõnis Laasfeld, Ago Rinken
Publikováno v:
Open Biology, Vol 12, Iss 6 (2022)
M4 muscarinic acetylcholine receptor is a G protein-coupled receptor (GPCR) that has been associated with alcohol and cocaine abuse, Alzheimer's disease, and schizophrenia which makes it an interesting drug target. For many GPCRs, the high-affinity f
Externí odkaz:
https://doaj.org/article/b405fccf134046ecba9658ded3d36898