Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ago, Argonaute"'
Publikováno v:
Non-coding RNA Research
Non-coding RNA Research, Vol 4, Iss 4, Pp 141-154 (2019)
Non-coding RNA Research, Vol 4, Iss 4, Pp 141-154 (2019)
Abstarct: Plant specific miRNAs (Novel miRNAs) are well known to perform distinctive functions in biological processes. Identification of new miRNAs is necessary to understand their gene regulation. Degradome provides an opportunity to explore the mi
Publikováno v:
International Immunopharmacology
SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper-inflammatory reaction named cytokine storm is occurred in patients with severe/c
Autor:
Ji Wu, Tian Qin, Yimin Mao, Jianxin Zheng, Tai-hua Yang, Yi Zhang, Hong Zhou, Feng Xue, Qiang Xia, Jinchuan Liu, Honglin Wang, Xiangqian Gu, Yuanjia Tang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1789-1807 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1789-1807 (2021)
Background & Aims Sustained c-Jun N-terminal kinase (JNK) activation plays a major role in drug-induced liver injury (DILI). Stress-responsive microRNA-31 (miR-31) has been implicated in regulating different cellular damage, and JNK activation could
Autor:
Qiming Zheng, Gonghui Li, Liya Wang, Zeyi Lu, Minxiao Jiang, Danyang Shen, Lifeng Ding, Liqun Xia, Huan Wang, Ruyue Wang
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100974-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100974-(2021)
Highlights • SncRNAs contribute to the progress of renal cell carcinoma. • SncRNAs are promising biomarkers for diagnosis and prognosis of renal cell carcinoma. • Despite the potential of sncRNA-based cancer therapy, some obstacles remain, incl
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 82-102 (2017)
Redox Biology
Redox Biology
Metabolic diseases such as type 2 diabetes are a major public health issue worldwide. These diseases are often linked to a dysfunctional adipose tissue. Fat is a large, heterogenic, pleiotropic and rather complex tissue. It is found in virtually all
Autor:
Kevin L. Greason, Qiang Chai, Tong Lu, John M. Stulak, Li Qun Wu, Hon Chi Lee, Xiao Li Wang, Win Kuang Shen, Lyle D. Joyce, Richard C. Daly, Tian You Ling, Yong Mei Cha
Publikováno v:
BBA Clinical
The L-type calcium channel (LTCC) is one of the major ion channels that are known to be associated with the electrical remodeling of atrial fibrillation (AF). In AF, there is significant downregulation of the LTCC, but the underlying mechanism for su
Autor:
Mark Blaxter, Amy H. Buck
Publikováno v:
Biochemical Society Transactions
Buck, A H & Blaxter, M 2013, ' Functional diversification of Argonautes in nematodes : an expanding universe ', Biochemical Society Transactions, vol. 41, no. 4, pp. 881-6 . https://doi.org/10.1042/BST20130086
Buck, A H & Blaxter, M 2013, ' Functional diversification of Argonautes in nematodes : an expanding universe ', Biochemical Society Transactions, vol. 41, no. 4, pp. 881-6 . https://doi.org/10.1042/BST20130086
In the last decade, many diverse RNAi (RNA interference) pathways have been discovered that mediate gene silencing at epigenetic, transcriptional and post-transcriptional levels. The diversity of RNAi pathways is inherently linked to the evolution of
Publikováno v:
Advanced Drug Delivery Reviews
Advanced Drug Delivery Reviews, 65(3), 348-356. Elsevier
Koppers-Lalic, D, Hogenboom, M M, Middeldorp, J M & Pegtel, D M 2013, ' Virus-modified exosomes for targeted RNA delivery; a new approach in nanomedicine ', Advanced Drug Delivery Reviews, vol. 65, no. 3, pp. 348-356 . https://doi.org/10.1016/j.addr.2012.07.006
Advanced Drug Delivery Reviews, 65(3), 348-356. Elsevier
Koppers-Lalic, D, Hogenboom, M M, Middeldorp, J M & Pegtel, D M 2013, ' Virus-modified exosomes for targeted RNA delivery; a new approach in nanomedicine ', Advanced Drug Delivery Reviews, vol. 65, no. 3, pp. 348-356 . https://doi.org/10.1016/j.addr.2012.07.006
A major goal in biomedical research is to clinically reverse the cause of disease rather than treating the symptoms. Gene therapy has the potential to meet this goal and the discovery of RNA interference (RNAi) has lead to a new class of highly selec
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Akademický článek
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