Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Agnieszka Stadnik"'
Autor:
Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Je Yeong Sone, Thomas Moore, Dorothy DeBiasse, Agnieszka Stadnik, Justine J. Lee, Robert Shenkar, Janne Koskimäki, Miguel A. Lopez-Ramirez, Douglas A. Marchuk, Mark H. Ginsberg, Mark L. Kahn, Changbin Shi, Issam A. Awad
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type
Externí odkaz:
https://doaj.org/article/05cc7d1857bb4df3a29deb810717fcd3
Autor:
Abhinav Srinath, Bingqing Xie, Ying Li, Je Yeong Sone, Sharbel Romanos, Chang Chen, Anukriti Sharma, Sean Polster, Pieter C. Dorrestein, Kelly C. Weldon, Dorothy DeBiasse, Thomas Moore, Rhonda Lightle, Janne Koskimäki, Dongdong Zhang, Agnieszka Stadnik, Kristina Piedad, Matthew Hagan, Abdallah Shkoukani, Julián Carrión-Penagos, Dehua Bi, Le Shen, Robert Shenkar, Yuan Ji, Ashley Sidebottom, Eric Pamer, Jack A. Gilbert, Mark L. Kahn, Mark D’Souza, Dinanath Sulakhe, Issam A. Awad, Romuald Girard
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-15 (2023)
Srinath, Xie et al. analyze plasma metabolites present in patients with cerebral cavernous angiomas. Cholic acid and hypoxanthine are found in those with Cavernous Angioma disease whilst arachidonic and linoleic acids are found in Cavernous Angioma p
Externí odkaz:
https://doaj.org/article/f125c70ee54e447c80e887a9ef5a5e18
Autor:
Sean P. Polster, Anukriti Sharma, Ceylan Tanes, Alan T. Tang, Patricia Mericko, Ying Cao, Julián Carrión-Penagos, Romuald Girard, Janne Koskimäki, Dongdong Zhang, Agnieszka Stadnik, Sharbel G. Romanos, Seán B. Lyne, Robert Shenkar, Kimberly Yan, Cornelia Lee, Amy Akers, Leslie Morrison, Myranda Robinson, Atif Zafar, Kyle Bittinger, Helen Kim, Jack A. Gilbert, Mark L. Kahn, Le Shen, Issam A. Awad
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Gut microbiome has been linked to cavernous angioma (CA), a common vascular disease, but the role in humans remains unclear. Here, the authors combine 16S rRNA sequencing and shotgun metagenomics to profile the microbiome in a large cohort of human s
Externí odkaz:
https://doaj.org/article/79327732fdd1439bb531e46396ad13b9
Autor:
Kris A Christensen, Eric B Rondeau, David R Minkley, Jong S Leong, Cameron M Nugent, Roy G Danzmann, Moira M Ferguson, Agnieszka Stadnik, Robert H Devlin, Robin Muzzerall, Michael Edwards, William S Davidson, Ben F Koop
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247083 (2021)
Externí odkaz:
https://doaj.org/article/c174df4134f940dd80228af20d4f12bc
Autor:
Kris A Christensen, Eric B Rondeau, David R Minkley, Jong S Leong, Cameron M Nugent, Roy G Danzmann, Moira M Ferguson, Agnieszka Stadnik, Robert H Devlin, Robin Muzzerall, Michael Edwards, William S Davidson, Ben F Koop
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204076 (2018)
Arctic charr have a circumpolar distribution, persevere under extreme environmental conditions, and reach ages unknown to most other salmonids. The Salvelinus genus is primarily composed of species with genomes that are structured more like the ances
Externí odkaz:
https://doaj.org/article/35a834810e304bcb83ccec1a9f4648b8
Autor:
Matthew J. Hagan, Robert Shenkar, Abhinav Srinath, Sharbel G. Romanos, Agnieszka Stadnik, Mark L. Kahn, Douglas A. Marchuk, Romuald Girard, Issam A. Awad
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Cerebral cavernous malformations (CCMs) are hemorrhagic neurovascular lesions that affect more than 1 million people in the United States. Rapamycin inhibits CCM development and bleeding in murine models. The appropriate dosage to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f73b3662862ad8c90d3668f2d5e66df
https://doi.org/10.1021/acsptsci.2c00006
https://doi.org/10.1021/acsptsci.2c00006
Autor:
Ying Li, Romuald Girard, Abhinav Srinath, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Thom Moore, Dorothy Debiasse, Mira Antonopoulos, Akash Bindal, Heba Ali, Agnieszka Stadnik, Justine Lee, Miguel A Lopez-Ramirez, Changbin Shi, Issam A Awad
Publikováno v:
Stroke. 54
Introduction: Cavernous Angiomas (CAs) are vascular malformations characterized by clusters of blood-filled capillary spaces lined by “leaky” endothelium. While mutations in endothelial cells have long been recognized as necessary for lesion gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf5e8d5c136abe14f99fd162e8c1063
https://doi.org/10.1161/str.54.suppl_1.tmp15
https://doi.org/10.1161/str.54.suppl_1.tmp15
Autor:
Stephanie F Hage, Matthew J Hagan, Agnieszka Stadnik, Justine Lee, Sharbel G Romanos, Abhinav Srinath, Robert Shenkar, Romuald Girard, Jianbo Hu, Connie Lee, Issam A Awad
Publikováno v:
Stroke. 54
Background: Cerebral cavernous malformation is a common lesion affecting more than a million Americans, with potential severe sequelae. It is unclear how socioeconomic status (SES) and race influence access to specialized care, and the enrollment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb9c751a2a1a1ee352778a9c1462171
https://doi.org/10.1161/str.54.suppl_1.hup14
https://doi.org/10.1161/str.54.suppl_1.hup14
Autor:
Stephanie F Hage, Agnieszka Stadnik, Justine Lee, Kelly D Flemming, Helen Kim, Michel T Torbey, Judy Huang, Carolina Mendoza-Puccini, James I Koenig, Richard E Thompson, Timothy J Carroll, Romuald Girard, Robert Shenkar, Daniel F Hanley, Issam A Awad
Publikováno v:
Stroke. 54
Background: Quantitative susceptibility mapping (QSM) is a measure of iron content, and ≥6% increase in QSM has been correlated with new hemorrhage in previously stable cavernous angiomas. Longitudinal changes in QSM are not known in cavernous angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c866a8a9e63d12164462081287c3b505
https://doi.org/10.1161/str.54.suppl_1.114
https://doi.org/10.1161/str.54.suppl_1.114
Autor:
Kelly Flemming, Jay Mandrekar, William Harmsen, Helen Kim, Jeffrey Nelson, Giuseppe S Lanzino, Judy Huang, Dan Hanley, Agnieszka Stadnik, Michel T Torbey, Richard Thompson, Kevin Treine, Issam A Awad
Publikováno v:
Stroke. 54
Background: Cerebral cavernous angiomas with symptomatic hemorrhage (CASH) carry highest rebleed rates and are targeted for novel interventions. A multisite clinical trial readiness project (clinicaltrials.gov NCT03652181) aims to identify clinical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83ca1382f6d4568953568fd7c0fe0f30
https://doi.org/10.1161/str.54.suppl_1.121
https://doi.org/10.1161/str.54.suppl_1.121