Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Agnieszka Rybak-Wolf"'
Autor:
Annett Boeddrich, Christian Haenig, Nancy Neuendorf, Eric Blanc, Andranik Ivanov, Marieluise Kirchner, Philipp Schleumann, Irem Bayraktaroğlu, Matthias Richter, Christine Mirjam Molenda, Anje Sporbert, Martina Zenkner, Sigrid Schnoegl, Christin Suenkel, Luisa-Sophie Schneider, Agnieszka Rybak-Wolf, Bianca Kochnowsky, Lauren M. Byrne, Edward J. Wild, Jørgen E. Nielsen, Gunnar Dittmar, Oliver Peters, Dieter Beule, Erich E. Wanker
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-32 (2023)
Abstract Background Alzheimer’s disease (AD) is characterized by the intra- and extracellular accumulation of amyloid-β (Aβ) peptides. How Aβ aggregates perturb the proteome in brains of patients and AD transgenic mouse models, remains largely u
Externí odkaz:
https://doaj.org/article/84f66523eef540e7aa35e8b03a0fbf0e
Autor:
Gizem Inak, Agnieszka Rybak-Wolf, Pawel Lisowski, Tancredi M. Pentimalli, René Jüttner, Petar Glažar, Karan Uppal, Emanuela Bottani, Dario Brunetti, Christopher Secker, Annika Zink, David Meierhofer, Marie-Thérèse Henke, Monishita Dey, Ummi Ciptasari, Barbara Mlody, Tobias Hahn, Maria Berruezo-Llacuna, Nikos Karaiskos, Michela Di Virgilio, Johannes A. Mayr, Saskia B. Wortmann, Josef Priller, Michael Gotthardt, Dean P. Jones, Ertan Mayatepek, Werner Stenzel, Sebastian Diecke, Ralf Kühn, Erich E. Wanker, Nikolaus Rajewsky, Markus Schuelke, Alessandro Prigione
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Leigh syndrome (LS) is a severe neurometabolic disorder which lacks effective models. Here, the authors developed human neuronal models of LS carrying mutations in SURF1 which show impaired neuronal morphogenesis due to metabolic deficiencies.
Externí odkaz:
https://doaj.org/article/7c5258ec4a0c4d51b4034db5722f87a1
Autor:
Agnieszka Rybak-Wolf, Mireya Plass
Publikováno v:
Molecules, Vol 26, Iss 17, p 5113 (2021)
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder that heavily burdens healthcare systems worldwide. There is a significant requirement to understand the still unknown molecular mechanisms underlying AD. Current evi
Externí odkaz:
https://doaj.org/article/3db4d741058d4e0a9815370a8d96dc5a
Autor:
Sabine Seeler, Maria Schertz Andersen, Tamas Sztanka-Toth, Mateja Rybiczka-Tešulov, Marleen H. van den Munkhof, Chi-Chih Chang, Muyesier Maimaitili, Morten Trillingsgaard Venø, Thomas Birkballe Hansen, R. Jeroen Pasterkamp, Agnieszka Rybak-Wolf, Mark Denham, Nikolaus Rajewsky, Lasse Sommer Kristensen, Jørgen Kjems
Publikováno v:
Seeler, S, Andersen, M S, Sztanka-Toth, T, Rybiczka-Tešulov, M, van den Munkhof, M H, Chang, C C, Maimaitili, M, Venø, M T, Hansen, T B, Pasterkamp, R J, Rybak-Wolf, A, Denham, M, Rajewsky, N, Kristensen, L S & Kjems, J 2023, ' A Circular RNA Expressed from the FAT3 Locus Regulates Neural Development ', Molecular Neurobiology, vol. 60, pp. 3239–3260 . https://doi.org/10.1007/s12035-023-03253-7
Circular RNAs (circRNAs) are key regulators of cellular processes, are abundant in the nervous system, and have putative regulatory roles during neural differentiation. However, the knowledge about circRNA functions in brain development is limited. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654b9dfdd733d23a00cf61347ad87d4e
https://pure.au.dk/portal/da/publications/a-circular-rna-expressed-from-the-fat3-locus-regulates-neural-development(e73d6302-c507-4020-9962-5cbf3077cf5f).html
https://pure.au.dk/portal/da/publications/a-circular-rna-expressed-from-the-fat3-locus-regulates-neural-development(e73d6302-c507-4020-9962-5cbf3077cf5f).html
Autor:
Carlos Alfonso-Gonzalez, Ivano Legnini, Sarah Holec, Laura Arrigoni, Hasan Can Ozbulut, Fernando Mateos, David Koppstein, Agnieszka Rybak-Wolf, Ulrike Bönisch, Nikolaus Rajewsky, Valérie Hilgers
Publikováno v:
Cell
The generation of distinct messenger RNA isoforms through alternative RNA processing modulates the expression and function of genes, often in a cell-type-specific manner. Here, we assess the regulatory relationships between transcription initiation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be45e3b1161b4456ad8bcfed4150a2f0
http://edoc.mdc-berlin.de/23360/1/23360oa.pdf
http://edoc.mdc-berlin.de/23360/1/23360oa.pdf
Publikováno v:
Nature Reviews Neurology.
Autor:
Anna Oliveras Martinez, Cledi Alicia Cerda Jara, Guido Mastrobuoni, Andrew Woehler, Stefan Kempa, Anastasiya Boltengagen, Tale Hessler, Ricardo Wurmus, Alessandra Zappulo, Agnieszka Rybak-Wolf, Lisa Emmenegger, Nikolaus Rajewsky, Ivano Legnini, Robert P. Zinzen
Organoids derived from stem cells become increasingly important to study human development and to model disease. However, methods are needed to control and study spatio-temporal patterns of gene expression in organoids. To this aim, we combined optog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d7ae1b7891b128f8e583e80ea3118c
http://edoc.mdc-berlin.de/21329/1/21329oa.pdf
http://edoc.mdc-berlin.de/21329/1/21329oa.pdf
Autor:
Carlos Alfonso-Gonzalez, Ivano Legnini, Sarah Holec, Laura Arrigoni, Ulrike Bönisch, Agnieszka Rybak-Wolf, Nikolaus Rajewsky, Valerie Hilgers
Publikováno v:
SSRN Electronic Journal.
Autor:
Mireya Plass, Agnieszka Rybak-Wolf
Publikováno v:
Molecules
Dipòsit Digital de la UB
Universidad de Barcelona
Molecules, Vol 26, Iss 5113, p 5113 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
Molecules, Vol 26, Iss 5113, p 5113 (2021)
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder that heavily burdens healthcare systems worldwide. There is a significant requirement to understand the still unknown molecular mechanisms underlying AD. Current evi
Autor:
Agnieszka Rybak-Wolf, Gizem Inak, Nikolaus Rajewsky, Carmen Menacho-Pando, Stephanie Le, Karl W. Kafitz, Christine R. Rose, Alessandro Prigione, Laura Petersilie
Publikováno v:
Journal of Visualized Experiments.
Mitochondrial diseases represent the largest class of inborn errors of metabolism and are currently incurable. These diseases cause neurodevelopmental defects whose underlying mechanisms remain to be elucidated. A major roadblock is the lack of effec