Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Agnieszka Piekielko-Witkowska"'
Autor:
Magdalena Ambrożek-Latecka, Piotr Kozlowski, Grażyna Hoser, Magdalena Bandyszewska, Karolina Hanusek, Dominika Nowis, Jakub Gołąb, Małgorzata Grzanka, Agnieszka Piekiełko-Witkowska, Luise Schulz, Franziska Hornung, Stefanie Deinhardt-Emmer, Ewa Kozlowska, Tomasz Skirecki
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Inflammasome assembly is a potent mechanism responsible for the host protection against pathogens, including viruses. When compromised, it can allow viral replication, while when disrupted, it can perpetuate pathological responses by IL-1 si
Externí odkaz:
https://doaj.org/article/98e3ed4e09be4e00bd7997b797d253b2
Autor:
Rodrigo Moreno-Reyes, Ulla Feldt-Rasmussen, Agnieszka Piekiełko-Witkowska, Adriana Gaspar da Rocha, Corin Badiu, Josef Köhrle, Leonidas Duntas
Publikováno v:
European Thyroid Journal, Vol 13, Iss 1, Pp 1-6 (2024)
In 2022, the European Chemicals Agency (ECHA) made a statement concluding that iodine is an endocrine disruptor (ED). We stress the fact that the ECHA opinion ECHA/BPC/357/2022 is based on their misguidedly zooming in on exclusively the biocidal prod
Externí odkaz:
https://doaj.org/article/f43f9cf473704c629d22af9f293b301c
Autor:
Piotr Popławski, Weronika Zarychta-Wiśniewska, Anna Burdzińska, Joanna Bogusławska, Anna Adamiok-Ostrowska, Karolina Hanusek, Beata Rybicka, Alex Białas, Helena Kossowska, Roksana Iwanicka-Nowicka, Marta Koblowska, Leszek Pączek, Agnieszka Piekiełko-Witkowska
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/76e44e770bb14558b9f21bc18919d4d2
Autor:
Piotr Popławski, Weronika Zarychta-Wiśniewska, Anna Burdzińska, Joanna Bogusławska, Anna Adamiok-Ostrowska, Karolina Hanusek, Beata Rybicka, Alex Białas, Helena Kossowska, Roksana Iwanicka-Nowicka, Marta Koblowska, Leszek Pączek, Agnieszka Piekiełko-Witkowska
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Advanced renal cell carcinoma (RCC) is therapeutically challenging. RCC progression is facilitated by mesenchymal stem/stromal cells (MSCs) that exert remarkable tumor tropism. The specific mechanisms mediating MSCs’ migration t
Externí odkaz:
https://doaj.org/article/830552eccf1f432e9f690d207d53599c
Publikováno v:
European Thyroid Journal, Vol 11, Iss 1, Pp 1-16 (2023)
Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The two major clinical manifestations of AITD are Graves’ disease and Hashimoto’s thyroiditis (HT). AITD is characterized by lymphocytic infiltrat ion of the thyroid g
Externí odkaz:
https://doaj.org/article/a930bf935ee344ff98f60072b3de2534
Autor:
Piotr Poplawski, Saleh Alseekh, Urszula Jankowska, Bozena Skupien-Rabian, Roksana Iwanicka-Nowicka, Helena Kossowska, Anna Fogtman, Beata Rybicka, Joanna Bogusławska, Anna Adamiok-Ostrowska, Karolina Hanusek, Jan Hanusek, Marta Koblowska, Alisdair R. Fernie, Agnieszka Piekiełko-Witkowska
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. The molecules (proteins, metabolites) secreted by tumors affect their extracellular milieu to support cancer progression. If secreted in amounts d
Externí odkaz:
https://doaj.org/article/a7f4e4992da94a72a4200134ec3d9659
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2482 (2021)
The nucleoli are membrane-less nuclear substructures that govern ribosome biogenesis and participate in multiple other cellular processes such as cell cycle progression, stress sensing, and DNA damage response. The proper functioning of these organel
Externí odkaz:
https://doaj.org/article/a69f6e7c916449d9a131e41621216f30
Autor:
Piotr Popławski, Jacek R Wiśniewski, Eddy Rijntjes, Keith Richards, Beata Rybicka, Josef Köhrle, Agnieszka Piekiełko-Witkowska
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190179 (2017)
Type 1 iodothyronine deiodinase (DIO1) contributes to deiodination of 3,5,3',5'-tetraiodo-L-thyronine (thyroxine, T4) yielding of 3,5,3'-triiodothyronine (T3), a powerful regulator of cell differentiation, proliferation, and metabolism. Our previous
Externí odkaz:
https://doaj.org/article/1f5758f2642949b589695861cc46cb79
Autor:
Anna Wojcicka, Agnieszka Piekielko-Witkowska, Hanna Kedzierska, Beata Rybicka, Piotr Poplawski, Joanna Boguslawska, Adam Master, Alicja Nauman
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97624 (2014)
Thyroid hormone receptor beta (THRB) gene is commonly deregulated in cancers and, as strengthened by animal models, postulated to play a tumor-suppressive role. Our previous studies revealed downregulation of THRB in clear cell renal cell carcinoma (
Externí odkaz:
https://doaj.org/article/b4bc2b432cf4431f9f593115fbc66c2f
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24541 (2011)
Type 1 iodothyronine deiodinase (DIO1) catalyses the conversion of prohormone thyroxine to the active thyroid hormone 3,3',5-triiodothyronine (T3), important regulator of cell proliferation and differentiation. DIO1 expression is reduced in the most
Externí odkaz:
https://doaj.org/article/d64681f4b52d4f6195243f8034cd3da1