Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Agnieszka Krakowiak"'
Autor:
Agnieszka Krakowiak, Sylwia Pietrasik
Publikováno v:
Biology, Vol 12, Iss 6, p 875 (2023)
Redox balance is important for the homeostasis of normal cells, but also for the proliferation, progression, and survival of cancer cells. Both oxidative and reductive stress can be harmful to cells. In contrast to oxidative stress, reductive stress
Externí odkaz:
https://doaj.org/article/86aedc561f444c81905bd359430e4a04
Autor:
Patrycja Szczupak, Malgorzata Sierant, Ewelina Wielgus, Ewa Radzikowska-Cieciura, Katarzyna Kulik, Agnieszka Krakowiak, Paulina Kuwerska, Grazyna Leszczynska, Barbara Nawrot
Publikováno v:
Cells, Vol 11, Iss 9, p 1522 (2022)
The bacterial enzyme tRNA 2-selenouridine synthase (SelU) is responsible for the conversion of 5-substituted 2-thiouridine (R5S2U), present in the anticodon of some bacterial tRNAs, into 5-substituted 2-selenouridine (R5Se2U). We have already demonst
Externí odkaz:
https://doaj.org/article/3aeb9907943547ef934c4e0aa8fd7698
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 607 (2022)
In this study, we present a new selenium derivative, 2′-deoxyguanosine-5′-O-selenophosphate (dGMPSe), synthesized by the oxathiaphospholane method and adapted here for the synthesis of nucleoside selenophosphates. Using biochemical assays (HPLC-
Externí odkaz:
https://doaj.org/article/7ff879fb539a42b691cb416a6fb214ff
Autor:
Tomasz Frączek, Rafał Kamiński, Agnieszka Krakowiak, Evelien Naessens, Bruno Verhasselt, Piotr Paneth
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 9-16 (2018)
In search of new non-nucleoside reverse transcriptase inhibitors (NNRTIs) with improved solubility, two series of novel diaryl ethers with phenacyl moiety were designed and evaluated for their HIV-1 reverse transcriptase inhibition potentials. All co
Externí odkaz:
https://doaj.org/article/55073517fbfe4b95b24591fc8af6d0c0
Autor:
Marcin Kolasa, Grzegorz Galita, Ireneusz Majsterek, Ewa Kucharska, Katarzyna Czerczak, Joanna Wasko, Angelika Becht, Justyna Fraczyk, Anna Gajda, Lukasz Pietrzak, Lukasz Szymanski, Agnieszka Krakowiak, Zbigniew Draczynski, Beata Kolesinska
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13584 (2021)
The aim of the research was to check whether it is possible to use fragments of type IV collagen to obtain, as a result of self-assembling, stable spatial structures that could be used to prepare new materials useful in regenerative medicine. Collage
Externí odkaz:
https://doaj.org/article/9a14a48f361f45e8bca227edf3de6991
Autor:
Renata Kaczmarek, Ewa Radzikowska, Barbara Mikołajczyk, Dariusz Korczyński, Kraig A. Wheeler, Barbara Nawrot, Agnieszka Krakowiak, Tomasz Pawlak, Janina Baraniak, Piotr Guga
Publikováno v:
RSC Advances. 10:35185-35197
3′-N-(2-Thio-1,3,2-oxathiaphospholane) derivatives of 5′-O-DMT-3′-amino-2′,3′-dideoxy-ribonucleosides (NOTP-N), that bear a 4,4-unsubstituted, 4,4-dimethyl, or 4,4-pentamethylene substituted oxathiaphospholane ring, were synthesized. Within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240413e3490a54231fe489d32382148d
https://doi.org/10.1039/d0ra04987e
https://doi.org/10.1039/d0ra04987e
Autor:
Patrycja Szczupak, Ewa Radzikowska-Cieciura, Katarzyna Kulik, Rafał Madaj, Małgorzata Sierant, Agnieszka Krakowiak, Barbara Nawrot
Publikováno v:
Bioorganic chemistry. 122
Bacterial tRNA 2-selenouridine synthase (SelU) in vitro converts S2U-RNA to its selenium analog (Se2U-RNA) in a two-step process: (i) geranylation of S2U-RNA (with geranyl pyrophosphate, gePP), and (ii) selenation of the resulting geS2U-RNA (with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5da16607edaf7c4606c4b12a98be46d
https://pubmed.ncbi.nlm.nih.gov/35306417
https://pubmed.ncbi.nlm.nih.gov/35306417
Publikováno v:
International Journal of Molecular Sciences
In this study, we present a new selenium derivative, 2′-deoxyguanosine-5′-O-selenophosphate (dGMPSe), synthesized by the oxathiaphospholane method and adapted here for the synthesis of nucleoside selenophosphates. Using biochemical assays (HPLC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::975e36171d9c079295226fe975fd1459
https://pubmed.ncbi.nlm.nih.gov/35054788
https://pubmed.ncbi.nlm.nih.gov/35054788
Autor:
Beata Kocoń-Rębowska, Agnieszka Krakowiak, Renata Kaczmarek, Anna Maciaszek, Danuta Piotrzkowska
Publikováno v:
Biochemical Pharmacology. 163:250-259
Phosphorothioate oligonucleotides (PS-oligos) containing sulfur atom attached in a nonbridging position to the phosphorus atom at one or more internucleotide bond(s) are often used in medicinal applications. Their hydrolysis in cellular media proceed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f7a7fb8d4320d935b41d45113f37826
https://doi.org/10.1016/j.bcp.2019.02.018
https://doi.org/10.1016/j.bcp.2019.02.018
Autor:
Rafał Dolot, Barbara Nawrot, Marta Pichlak, Renata Kaczmarek, Agnieszka Krakowiak, Artur Włodarczyk
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1866:130035
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54b0d8bcab488dd0bb8fdcaabaa739e7
https://doi.org/10.1016/j.bbagen.2021.130035
https://doi.org/10.1016/j.bbagen.2021.130035