Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Agnieszka Karkucińska-Więckowska"'
Autor:
Giampaolo Morciano, Saverio Marchi, Claudia Morganti, Luigi Sbano, Mart Bittremieux, Martijn Kerkhofs, Mariangela Corricelli, Alberto Danese, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski, Geert Bultynck, Carlotta Giorgi, Paolo Pinton
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 5, Pp 510-523 (2018)
Mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs) are highly specialized subcellular compartments that are shaped by ER subdomains juxtaposed to mitochondria but are biochemically distinct from pure ER and pure mitochondria. MAMs ar
Externí odkaz:
https://doaj.org/article/9a86411e114c4fd9b691591005cbf848
Autor:
Ines C. M. Simoes, Agnieszka Karkucinska-Wieckowska, Justyna Janikiewicz, Sylwia Szymanska, Maciej Pronicki, Pawel Dobrzyn, Michal Dabrowski, Agnieszka Dobrzyn, Paulo J. Oliveira, Hans Zischka, Yaiza Potes, Mariusz R. Wieckowski
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 995 (2020)
Nonalcoholic fatty liver disease (NAFLD) is characterized by the development of steatosis, which can ultimately compromise liver function. Mitochondria are key players in obesity-induced metabolic disorders; however, the distinct role of hypercaloric
Externí odkaz:
https://doaj.org/article/19864496d3dd43d88c771bc5876e8caf
Autor:
Afshan N Malik, Inês C.M. Simões, Hannah S. Rosa, Safa Khan, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski
Publikováno v:
Cells, Vol 8, Iss 10, p 1222 (2019)
Non-alcoholic fatty liver disease (NAFLD), an increasingly prevalent and underdiagnosed disease, is postulated to be caused by hepatic fat mediated pathological mechanisms. Mitochondrial dysfunction is proposed to be involved, but it is not known whe
Externí odkaz:
https://doaj.org/article/3fe6d9ac586040f487f9881781eb93a8
Autor:
Mariusz R. Wieckowski, Paolo Pinton, Maciej Pronicki, Jerzy Duszynski, Carlotta Giorgi, Joanna Szczepanowska, Gyorgy Szabadkai, Agnieszka Karkucinska-Wieckowska, Magdalena Lebiedzinska, Jan M. Suski
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 8, Pp 5373-5389 (2011)
Reactive oxygen species (ROS) are wieldy accepted as one of the main factors of the aging process. These highly reactive compounds modify nucleic acids, proteins and lipids and affect the functionality of mitochondria in the first case and ultimately
Externí odkaz:
https://doaj.org/article/16ad849a74164780a55fc5c615872f39
Autor:
Joanna Trubicka, Maria Łastowska, Agnieszka Karkucińska-Więckowska, Magdalena Niemira, Maria Ejmont, Agnieszka Sowińska, Maciej Pronicki, Ewa Matyja, Wiesława Grajkowska
Publikováno v:
Folia Neuropathologica, Vol 61, Iss 2, Pp 121-128 (2023)
BCOR is expressed in a new brain tumour entity, i.e. ‘CNS tumour with BCOR internal tandem duplication’ (HGNET BCOR) but not in several other high grade paediatric brain tumours investigated. Immunohistochemical detection of BCOR expression may t
Externí odkaz:
https://doaj.org/article/a8029630c0e24ea59e0970ff420734b2
Autor:
Edyta Szymanska, Sylwia Szymanska, Agnieszka Karkucińska-Więckowska, Aldona Wierzbicka, Jaroslaw Kierkus, Maciej Dadalski
Publikováno v:
Gastrointestinal Disorders, Vol 5, Iss 1, Pp 28-36 (2023)
Background: Fecal calprotectin (FCP) is a highly sensitive biomarker of intestinal inflammation widely used in diagnostics and monitoring of inflammatory bowel disease (IBD). Immunohistochemical assessment of calprotectin in the bowel mucosa is not a
Externí odkaz:
https://doaj.org/article/d8a4f6cd972b42c38bcb075eacfd2a6b
Autor:
Maria Łastowska, Ewa Matyja, Anna Sobocińska, Bartosz Wojtaś, Magdalena Niemira, Anna Szałkowska, Adam Krętowski, Agnieszka Karkucińska‐Więckowska, Magdalena Kaleta, Maria Ejmont, Magdalena Tarasińska, Marta Perek‐Polnik, Bożenna Dembowska‐Bagińska, Maciej Pronicki, Wiesława Grajkowska, Joanna Trubicka
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 6, Pp 565-576 (2021)
Abstract The majority of supratentorial ependymomas in children contain oncogenic fusions, such as ZFTA–RELA or YAP1‐MAMLD1. In contrast, posterior fossa (PF) ependymomas lack recurrent somatic mutations and are classified based on gene expressio
Externí odkaz:
https://doaj.org/article/7e8570c907ad436eb02c29b0dbf990be
Autor:
Maria Łastowska, Joanna Trubicka, Anna Sobocińska, Bartosz Wojtas, Magdalena Niemira, Anna Szałkowska, Adam Krętowski, Agnieszka Karkucińska-Więckowska, Magdalena Kaleta, Maria Ejmont, Marta Perek-Polnik, Bożenna Dembowska-Bagińska, Wiesława Grajkowska, Ewa Matyja
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Four molecular types of rare central nervous system (CNS) tumors have been recently identified by gene methylation profiling: CNS Neuroblastoma with FOXR2 activation (CNS NB-FOXR2), CNS Ewing Sarcoma Family Tumor with CIC alteration (CNS EFT
Externí odkaz:
https://doaj.org/article/2e546f93b82242a08cc7a0821eda5563
Autor:
Magdalena Kaleta, Anna Wakulińska, Agnieszka Karkucińska-Więckowska, Bożenna Dembowska-Bagińska, Wiesława Grajkowska, Maciej Pronicki, Maria Łastowska
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-7 (2019)
Abstract Background The most frequent histological types of rhabdomyosarcoma (RMS) in children are embryonal (ERMS) and alveolar (ARMS) tumours. The majority of ARMS are characterized by the presence of PAX3/7-FOXO1 gene fusion and have a worse progn
Externí odkaz:
https://doaj.org/article/b5f414a50ed24d0fbd961e73b690e4d5
Autor:
Joanna Trubicka, Małgorzata Szperl, Wiesława Grajkowska, Agnieszka Karkucińska-Więckowska, Magdalena Tarasińska, Katarzyna Falana, Bożenna Dembowska-Bagińska, Maria Łastowska
Publikováno v:
Folia Neuropathologica, Vol 54, Iss 1, Pp 23-30 (2016)
Rearrangements involving the ALK gene were identified in a variety of cancers, including paediatric tumour neuroblastoma where presence of ALK expression is also associated with adverse prognosis. Microarrays data indicate that ALK is expressed in an
Externí odkaz:
https://doaj.org/article/dced313c2ed642d2b65511b6a7556f50