Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Agnieszka J Nowak"'
Autor:
Anna Krzak, Agnieszka J. Nowak, Marcin Heljak, Jerzy Antonowicz, Tushar Garg, Michael Sumption
Publikováno v:
Polymers, Vol 16, Iss 5, p 606 (2024)
It is commonly acknowledged that polymer composites in service are often subjected to not only intricate mechanical loads but also harsh environmental conditions. The mechanical and thermal properties of five particular composites are explored here.
Externí odkaz:
https://doaj.org/article/fd83b68eec1d433da29d3529fb36d41b
Publikováno v:
Materials, Vol 17, Iss 1, p 16 (2023)
Due to the high interest in the use of glass/epoxy laminates in aerospace applications, aviation, and as cryogenic tanks, it is crucial to understand the behavior of composites under challenging environmental conditions. Polymer composites are expose
Externí odkaz:
https://doaj.org/article/e7a8f0b6dee1476da0ca773557cf9ec1
Autor:
Srdan Verstovsek, Steve Horrigan, Christopher P. Mill, Sunil Sharma, Steven M. Kornblau, Craig M. Crews, Taghi Manshouri, Baohua Sun, Kapil N. Bhalla, Prithviraj Bose, Agnieszka J Nowak, Tapan M. Kadia, Peng Qiu, Kimal Rajapakshe, Raffaella Soldi, David N. Saenz, Gautam Borthakur, Warren Fiskus, Dyana T. Saenz, Kanak Raina, Cristian Coarfa, Lucia Masarova, Joseph D. Khoury, Yimin Qian
Publikováno v:
Leukemia. 33(6)
Transformation of post-myeloproliferative neoplasms into secondary (s) AML exhibit poor clinical outcome. In addition to increased JAK-STAT and PI3K-AKT signaling, post-MPN sAML blast progenitor cells (BPCs) demonstrate increased nuclear β-catenin l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c056297cceeee15fce9aa3e9c09917
https://pubmed.ncbi.nlm.nih.gov/30575820
https://pubmed.ncbi.nlm.nih.gov/30575820
Autor:
Craig M. Crews, Yimin Qian, Joseph D. Khoury, Kevin Coleman, Andrew P. Crew, Cristian Coarfa, Christopher P. Mill, Li Zhang, Michael Wang, Kanak Raina, Baohua Sun, Neeraj Jain, Agnieszka J Nowak, Warren Fiskus, Angela Shen, Kimal Rajapakshe, Dyana T. Saenz, Kapil N. Bhalla
Publikováno v:
Leukemia. 32(2)
Bromodomain extraterminal protein (BETP) inhibitors transcriptionally repress oncoproteins and nuclear factor-κB (NF-κB) target genes that undermines the growth and survival of mantle cell lymphoma (MCL) cells. However, BET bromodomain inhibitor (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cba40c4b8c678a303dd714a22d3095
https://pubmed.ncbi.nlm.nih.gov/28663582
https://pubmed.ncbi.nlm.nih.gov/28663582
Autor:
Grzegorz, Chladek, Katarzyna, Basa, Jarosław, Żmudzki, Piotr, Malara, Agnieszka J, Nowak, Jacek, Kasperski
Publikováno v:
Acta of bioengineering and biomechanics. 18(3)
The purpose of this study was to investigate the effect of different plasticizing aging solutions on wear resistance and hardness of selected universal resin-based dental composites.Three light cured (one nanofilled, two microhybride) and one hybride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::020a5ae473b13fdd03559b393f685dd8
https://pubmed.ncbi.nlm.nih.gov/27840447
https://pubmed.ncbi.nlm.nih.gov/27840447
Autor:
Peng Qiu, Kimal Rajapakshe, Baohua Sun, Warren Fiskus, Christopher P. Mill, Craig M. Crews, Misun Kim, Agnieszka J Nowak, Kanak Raina, Srdan Verstovsek, Andrew P. Crew, Courtney D. DiNardo, Naveen Pemmaraju, Dyana T. Saenz, Cristian Coarfa, Kapil N. Bhalla, Tapan M. Kadia, Yimin Qian, Taghi Manshouri, Angela Shen, Kevin Coleman
Publikováno v:
Leukemia
The PROTAC (proteolysis-targeting chimera) ARV-825 recruits bromodomain and extraterminal (BET) proteins to the E3 ubiquitin ligase cereblon, leading to degradation of BET proteins, including BRD4. Although the BET-protein inhibitor (BETi) OTX015 cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f279a98d827d464d52f5b472fd8cd1b3
https://pubmed.ncbi.nlm.nih.gov/28042144
https://pubmed.ncbi.nlm.nih.gov/28042144
Autor:
Christoph W. Müller, Florence Baudin, Doris Lindner, Christian U. Stirnimann, Nga Ly-Hartig, Vladimir Rybin, Claudio Alfieri, Agnieszka J. Nowak
Publikováno v:
Journal of Biological Chemistry. 286:23388-23396
Drosophila Nurf55 is a component of different chromatin-modifying complexes, including the PRC2 (Polycomb repressive complex 2). Based on the 1.75-Å crystal structure of Nurf55 bound to histone H4 helix 1, we analyzed interactions of Nurf55 (Nurf55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c78f7b75870f11c70767a306ed7c354
https://doi.org/10.1074/jbc.m110.207407
https://doi.org/10.1074/jbc.m110.207407
Autor:
Yu Shen, Dyana T. Saenz, Thurika Ganesh, David N. Saenz, Gautam Borthakur, Kapil N. Bhalla, Vaishnavi Rao, Christopher P. Mill, Joseph D. Khoury, Steven M. Kornblau, Wendy Jin, Warren Fiskus, Marina Konopleva, Courtney D. DiNardo, Baohua Sun, Agnieszka J Nowak, Tianyu Cai, Tapan M. Kadia
Publikováno v:
Blood. 132:1351-1351
Bromodomain extra-terminal (BET) protein (BETP) family of chromatin reader proteins includes BRD4 that binds to acetylated lysine in the active chromatin and transcription factors (TFs) at enhancers and promoters, as well as increases RNA pol II (RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa48495a28a86e5044331fc345d3e512
https://doi.org/10.1182/blood-2018-99-113976
https://doi.org/10.1182/blood-2018-99-113976
Autor:
Sunil Sharma, Joseph D. Khoury, Gautam Borthakur, Kapil N. Bhalla, Christopher P. Mill, Courtney D. DiNardo, Roulan Han, Vaishnavi Rao, Wendy Jin, Tapan M. Kadia, David N. Saenz, Dyana T. Saenz, Thurika Ganesh, Warren Fiskus, Raffaella Soldi, Baohua Sun, Agnieszka J Nowak
Publikováno v:
Blood. 132:3930-3930
There is a clear need to develop novel therapies that would overcome differentiation block and eliminate AML stem/progenitor cells. Genetic and epigenetic dysregulation of enhancers regulates expressions of myeloid lineage transcriptional regulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04512d4392002900852a30cba74a688e
https://doi.org/10.1182/blood-2018-99-114198
https://doi.org/10.1182/blood-2018-99-114198
Autor:
David N. Saenz, Christopher P. Mill, Warren Fiskus, Dyana T. Saenz, Steven M. Kornblau, Kapil N. Bhalla, Baohua Sun, Agnieszka J Nowak, Courtney D. DiNardo
Publikováno v:
Cancer Research. 78:3884-3884
RUNX1 is a master-regulator transcription factor involved in normal and malignant hematopoiesis. In addition to chromosomal translocations involving the RUNX1 locus, somatic, heterozygous RUNX1 mutations commonly occur in MDS, CMML, as well as in sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3f0bfd99750b59c6cc35bd8dce7c637
https://doi.org/10.1158/1538-7445.am2018-3884
https://doi.org/10.1158/1538-7445.am2018-3884