Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Agnieszka E Zielinska"'
Autor:
Craig L. Doig, Agnieszka E. Zielinska, Rachel S. Fletcher, Lucy A. Oakey, Yasir S. Elhassan, Antje Garten, David Cartwright, Silke Heising, Ahmed Alsheri, David G. Watson, Cornelia Prehn, Jerzy Adamski, Daniel A. Tennant, Gareth G. Lavery
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Background Hexose-6-Phosphate Dehydrogenase (H6PD) is a generator of NADPH in the Endoplasmic/Sarcoplasmic Reticulum (ER/SR). Interaction of H6PD with 11β-hydroxysteroid dehydrogenase type 1 provides NADPH to support oxo-reduction of inacti
Externí odkaz:
https://doaj.org/article/8d9a163de0734bd78b8d622a8457c287
Autor:
Kelly Chiang, Agnieszka E. Zielinska, Abeer M. Shaaban, Maria Pilar Sanchez-Bailon, James Jarrold, Thomas L. Clarke, Jingxian Zhang, Adele Francis, Louise J. Jones, Sally Smith, Olena Barbash, Ernesto Guccione, Gillian Farnie, Matthew J. Smalley, Clare C. Davies
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3498-3513 (2017)
Summary: Breast cancer progression, treatment resistance, and relapse are thought to originate from a small population of tumor cells, breast cancer stem cells (BCSCs). Identification of factors critical for BCSC function is therefore vital for the d
Externí odkaz:
https://doaj.org/article/c87094c1b9fa49f294c1e88bb72d1739
Autor:
Celina Whalley, Charlotte Poxon, Gabriella L. Morley, Kasun Wanigasooriya, Lyndsey A Dunbar, Mark T. Drayson, Dee E McLoughlin, Saly Al-Taei, Mark I. Garvey, Beena Emmanuel, Golaleh McGinnell, Sian E Jossi, Megan Richter, Andrew D Beggs, Marisol Perez-Toledo, Joel D. Allen, Adam F. Cunningham, Eloise M Walker, Agnieszka E. Zielinska, Joanna Gray, Max Crispin, Joanna O'Neill, Erin L. Aldera, Adrian M Shields, David C. Wraith, Andrew Bosworth, Oliver J Pickles, Sian E Faustini, Claire Backhouse, Alex G. Richter, Daniel Ebanks, I. Michael Kidd, Danai Papakonstantinou, Yasunori Watanabe
Publikováno v:
Thorax
ObjectiveTo determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers.DesignA cross-sectional study of asymptomatic healthcare workers undertaken on 24/25 April 2020.SettingUniversity Hospita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd27dd511f0616b3ed2ed8baf05196f
https://doi.org/10.1136/thoraxjnl-2020-215414
https://doi.org/10.1136/thoraxjnl-2020-215414
Autor:
Adrian M Shields, Sian E Faustini, Marisol Perez-Toledo, Sian Jossi, Erin L Aldera, Joel D Allen, Saly Al-Taei, Claire Backhouse, Andrew Bosworth, Lyndsey Dunbar, Daniel Ebanks, Beena Emmanuel, Joanne Grey, I Michael Kidd, Golaeh McGinnell, Dee McLoughlin, Gabriella Morley, Joanne O'Neill, Danai Papakonstantinou, Oliver Pickles, Charlotte Poxon, Megan Richter, Eloise Walker, Kasun Wanigasooriya, Yasunori Watanabe, Celina Whalley, Agnieszka E Zielinska, Max Crispin, David C Wraith, Andrew D Beggs, Adam F Cunningham, Mark T Drayson, Alex G Richter
Background The correlates of protection against SARS-CoV-2 and their longevity remain unclear. Studies in severely ill individuals have identified robust cellular and humoral immune responses against the virus. Asymptomatic infection with SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246622c5430201e611af8644676956a6
Autor:
Andrew Ellis, Alex G. Richter, Oliver J Pickles, Eloise M Walker, Gabriella L. Morley, Craig Webster, Kasun Wanigasooriya, Andrew D Beggs, Celina Whalley, Andrew Bosworth, Dee E McLoughlin, Danai Papakonstantinou, Charlie Poxon, Agnieszka E. Zielinska, Tim Plant, I. Michael Kidd, Erin L. Aldera
Publikováno v:
Journal of Clinical Virology
Background In January 2020 reports of unidentified severe respiratory illness were described in Wuhan, China. A rapid expansion in cases affecting most countries around the globe led to major changes in the way people live their daily lives. In the U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d1adabd63d038a04a27a64b8247e24
http://europepmc.org/articles/PMC7244439
http://europepmc.org/articles/PMC7244439
Autor:
Jerzy Adamski, Gareth G. Lavery, David Cartwright, Rachel Fletcher, Ahmed Alsheri, Craig L. Doig, Daniel A. Tennant, Antje Garten, Lucy Oakey, Agnieszka E. Zielinska, Silke Heising, David G. Watson, Yasir S Elhassan, Cornelia Prehn
Publikováno v:
Skeletal muscle
Skeletal Muscle, Vol 10, Iss 1, Pp 1-13 (2020)
Skelet. Muscle 10:5 (2020)
Skeletal Muscle
Skeletal Muscle, Vol 10, Iss 1, Pp 1-13 (2020)
Skelet. Muscle 10:5 (2020)
Skeletal Muscle
Background Hexose-6-Phosphate Dehydrogenase (H6PD) is a generator of NADPH in the Endoplasmic/Sarcoplasmic Reticulum (ER/SR). Interaction of H6PD with 11β-hydroxysteroid dehydrogenase type 1 provides NADPH to support oxo-reduction of inactive to act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30b638177c3cdc208220a2eadc09d4f
https://strathprints.strath.ac.uk/75180/1/Doig_etal_SM_2020_Induction_of_the_nicotinamide_riboside_kinase_NAD_salvage_pathway.pdf
https://strathprints.strath.ac.uk/75180/1/Doig_etal_SM_2020_Induction_of_the_nicotinamide_riboside_kinase_NAD_salvage_pathway.pdf
Autor:
Yasir S Elhassan, Rachel Fletcher, Craig L. Doig, Daniel A. Tennant, Jerzy Adamski, David Cartwright, Antje Garten, Agnieszka E. Zielinska, David G. Watson, Gareth G. Lavery, A Alsheri, Lucy Oakey, Silke Heising
BackgroundHexose-6-Phosphate Dehydrogenase (H6PDH) is a generator of NADPH in the Endoplasmic/Sarcoplasmic Reticulum (ER/SR). Interaction of H6PDH with 11β-hydroxysteroid dehydrogenase type 1 provides NADPH to support oxo-reduction of inactive to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d357098bc48f9558ada441ca8f2650
https://doi.org/10.1101/567297
https://doi.org/10.1101/567297
Autor:
Kelly Chiang, Agnieszka E. Zielinska, Abeer M. Shaaban, Maria Pilar Sanchez-Bailon, James Jarrold, Thomas L. Clarke, Jingxian Zhang, Adele Francis, Louise J. Jones, Sally Smith, Olena Barbash, Ernesto Guccione, Gillian Farnie, Matthew J. Smalley, Clare C. Davies
Publikováno v:
Cell Reports
Cell Reports, Vol 21, Iss 12, Pp 3498-3513 (2017)
Cell Reports, Vol 21, Iss 12, Pp 3498-3513 (2017)
Summary Breast cancer progression, treatment resistance, and relapse are thought to originate from a small population of tumor cells, breast cancer stem cells (BCSCs). Identification of factors critical for BCSC function is therefore vital for the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::00806a6998cff3fa8612eb0980054ebf
https://ora.ox.ac.uk/objects/uuid:c8dac21c-ded6-4d62-9b35-2dc22ab73d57
https://ora.ox.ac.uk/objects/uuid:c8dac21c-ded6-4d62-9b35-2dc22ab73d57
Publikováno v:
Cell Biochemistry and Function
Glucocorticoids are important for skeletal muscle energy metabolism, regulating glucose utilization, insulin sensitivity, and muscle mass. Nicotinamide adenine dinucleotide phosphate‐dependent 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30755c4da861210c522d78c5be4a31c2
https://pubmed.ncbi.nlm.nih.gov/28749080
https://pubmed.ncbi.nlm.nih.gov/28749080
Autor:
Craig L. Doig, Mark S. Cooper, Gareth G. Lavery, Jamila Bashir, Agnieszka E. Zielinska, Paul M. Stewart
Publikováno v:
The Journal of Endocrinology
The activity of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts inactive cortisone (11-dehydrocorticosterone (11-DHC)) (in mice) into the active glucocorticoid (GC) cortisol (corticosterone in mice), can amplify tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc192397e93e6ef3a03d38ac2899044
https://doi.org/10.1530/joe-13-0494
https://doi.org/10.1530/joe-13-0494