Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Agnieszka Chomka"'
Autor:
Rachel Tanner, Iman Satti, Stephanie A. Harris, Matthew K. O'Shea, Deniz Cizmeci, Daniel O'Connor, Agnieszka Chomka, Magali Matsumiya, Rachel Wittenberg, Angela M. Minassian, Joel Meyer, Helen A. Fletcher, Helen McShane
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Tuberculosis (TB) remains a leading global cause of morbidity and mortality and an effective new vaccine is urgently needed. A major barrier to the rational development of novel TB vaccines is the lack of a validated immune correlate or biomarker of
Externí odkaz:
https://doaj.org/article/3a79f6ae1f1441c1bc01dc2dd53f6d80
Autor:
Thomas Krausgruber, Chris Schiering, Krista Adelmann, Oliver J. Harrison, Agnieszka Chomka, Claire Pearson, Philip P. Ahern, Matthew Shale, Mohamed Oukka, Fiona Powrie
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
How transcription factor T-bet and Th17 cells contribute to colitis remains incompletely understood. Here the authors identify T-bet as a negative regulator of IL-23R pathway activation and show that T-bet deficient T cells drive colitogenic Th17 res
Externí odkaz:
https://doaj.org/article/7468206667654e0d9f30482bda325b7b
Autor:
Helen A. Fletcher, Margaret A. Snowden, Bernard Landry, Wasima Rida, Iman Satti, Stephanie A. Harris, Magali Matsumiya, Rachel Tanner, Matthew K. O’Shea, Veerabadran Dheenadhayalan, Leah Bogardus, Lisa Stockdale, Leanne Marsay, Agnieszka Chomka, Rachel Harrington-Kandt, Zita-Rose Manjaly-Thomas, Vivek Naranbhai, Elena Stylianou, Fatoumatta Darboe, Adam Penn-Nicholson, Elisa Nemes, Mark Hatherill, Gregory Hussey, Hassan Mahomed, Michele Tameris, J Bruce McClain, Thomas G. Evans, Willem A. Hanekom, Thomas J. Scriba, Helen McShane
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
BCG vaccine confers only partial protection against tuberculosis. Here the authors show that the risk of tuberculosis infection and progression to disease in BCG-immunized children positively correlates with the frequency of activated HLA-DR+CD4+T ce
Externí odkaz:
https://doaj.org/article/edab3b0f77064ee189c1a3294bd52daa
Autor:
Helen A. Fletcher, Margaret A. Snowden, Bernard Landry, Wasima Rida, Iman Satti, Stephanie A. Harris, Magali Matsumiya, Rachel Tanner, Matthew K. O’Shea, Veerabadran Dheenadhayalan, Leah Bogardus, Lisa Stockdale, Leanne Marsay, Agnieszka Chomka, Rachel Harrington-Kandt, Zita-Rose Manjaly-Thomas, Vivek Naranbhai, Elena Stylianou, Fatoumatta Darboe, Adam Penn-Nicholson, Elisa Nemes, Mark Hatherill, Gregory Hussey, Hassan Mahomed, Michele Tameris, J. Bruce McClain, Thomas G. Evans, Willem A. Hanekom, Thomas J. Scriba, Helen McShane
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7, Article number: 11290 (2016); Published: 12 April 2016; Updated: 6 May 2016. The original version of this Article contained an error in the spelling of the author Mark Hatherill, which was incorrectly given as Mark Hatheril.
Externí odkaz:
https://doaj.org/article/b95da97828c544a898fe07abb1e26945
Autor:
Rachel, Tanner, Iman, Satti, Stephanie A, Harris, Matthew K, O'Shea, Deniz, Cizmeci, Daniel, O'Connor, Agnieszka, Chomka, Magali, Matsumiya, Rachel, Wittenberg, Angela M, Minassian, Joel, Meyer, Helen A, Fletcher, Helen, McShane
Publikováno v:
Frontiers in Immunology
Tuberculosis (TB) remains a leading global cause of morbidity and mortality and an effective new vaccine is urgently needed. A major barrier to the rational development of novel TB vaccines is the lack of a validated immune correlate or biomarker of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::096bd227aa0b2adb9999e5c8c997c8be
https://pubmed.ncbi.nlm.nih.gov/31998295
https://pubmed.ncbi.nlm.nih.gov/31998295
Autor:
Helen McShane, Bernard Landry, Matthew K. O'Shea, Thomas J. Scriba, Elena Stylianou, Gregory D Hussey, Julius Muller, Willem A. Hanekom, Stephanie A. Harris, Zita-Rose Manjaly Thomas, Hassan Mahomed, Lisa Stockdale, Iman Satti, Margaret A Snowden, Magali Matsumiya, Stanley Kimbung Mbandi, Leanne Marsay, J. Bruce McClain, Michele Tameris, Mark Hatherill, Rachel Tanner, Thomas G. Evans, Rachel Harrington-Kandt, Agnieszka Chomka, Helen A. Fletcher, Vivek Naranbhai
Publikováno v:
JCI Insight
Immune activation is associated with increased risk of tuberculosis (TB) disease in infants. We performed a case-control analysis to identify drivers of immune activation and disease risk. Among 49 infants who developed TB disease over the first 2 ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bbe2813fb511aa56af27ef21be0ebb
https://pubmed.ncbi.nlm.nih.gov/31697647
https://pubmed.ncbi.nlm.nih.gov/31697647
Autor:
Jacqueline D. Shields, Guy Emerton, Ida Lindeman, Thomas Krausgruber, Muzlifah Haniffa, Tomás Gomes, Ricardo J. Miragaia, Laura Jardine, Angela Riedel, Andrea Tucci, Natasha Whibley, Xi Chen, Ahmed N. Hegazy, Agnieszka Chomka, Fiona Powrie, Sarah A. Teichmann
Publikováno v:
Immunity
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Summary Non-lymphoid tissues (NLTs) harbor a pool of adaptive immune cells with largely unexplored phenotype and development. We used single-cell RNA-seq to characterize 35,000 CD4+ regulatory (Treg) and memory (Tmem) T cells in mouse skin and colon,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49f25d992a2621a88f1241554877cb5
Autor:
Julius Muller, Rachel Tanner, Magali Matsumiya, Margaret A. Snowden, Bernard Landry, Iman Satti, Stephanie A. Harris, Matthew K. O’Shea, Lisa Stockdale, Leanne Marsay, Agnieszka Chomka, Rachel Harrington-Kandt, Zita-Rose Manjaly Thomas, Vivek Naranbhai, Elena Stylianou, Stanley Kimbung Mbandi, Mark Hatherill, Gregory Hussey, Hassan Mahomed, Michele Tameris, J. Bruce McClain, Thomas G. Evans, Willem A. Hanekom, Thomas J. Scriba, Helen McShane, Helen A. Fletcher
Immune activation is associated with increased risk of tuberculosis (TB) disease in infants. We performed a case-control analysis to identify drivers of immune activation and disease risk. Among 49 infants who developed TB disease over the first two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bab979e8ce32010c1639197f3a1c59d
Autor:
Ricardo J. Miragaia, Sarah A. Teichmann, Angela Riedel, Muzlifah Haniffa, Fiona Powrie, Agnieszka Chomka, Ahmed N. Hegazy, Laura Jardine, Thomas Krausgruber, Jacqueline D. Shields, Guy Emerton, Ida Lindeman, Tomás Gomes
SummaryNon-lymphoid tissues (NLTs) harbour a pool of adaptive immune cells, the development and phenotype of which remains largely unexplored. Here, we used single-cell RNA-seq to characterise CD4+ regulatory (Treg) and memory (Tmem) T cells in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92da28d4b24bcbcb6d8dce6d5faa84a0
Autor:
Oliver J. Harrison, Ahmed N. Hegazy, Thomas Krausgruber, Elizabeth A. Wohlfert, Chris Schiering, Benjamin M. J. Owens, Anja Fröhlich, Johanna Pott, Julia Bollrath, Yasmine Belkaid, Agnieszka Chomka, Thibault Griseri, Max Löhning, Padraic G. Fallon, Fiona Powrie, Krista Adelmann
Publikováno v:
Nature
FOXP3(+) regulatory T cells (Treg cells) are abundant in the intestine, where they prevent dysregulated inflammatory responses to self and environmental stimuli. It is now appreciated that Treg cells acquire tissue-specific adaptations that facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a5a7bcd76fb27401d5dc006021ac09
https://doi.org/10.1038/nature13577
https://doi.org/10.1038/nature13577