Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Agnieszka B. Olejniczak"'
Autor:
Beata Donarska, Joanna Cytarska, Dominika Kołodziej-Sobczak, Renata Studzińska, Daria Kupczyk, Angelika Baranowska-Łączkowska, Karol Jaroch, Paulina Szeliska, Barbara Bojko, Daria Różycka, Agnieszka B. Olejniczak, Wojciech Płaziński, Krzysztof Z. Łączkowski
Publikováno v:
Molecules, Vol 29, Iss 19, p 4716 (2024)
The presented study depicts the synthesis of 11 carborane–thiazole conjugates with anticancer activity, as well as an evaluation of their biological activity as inhibitors of two enzymes: tyrosinase and 11β-hydroxysteroid dehydrogenase type 1 (11
Externí odkaz:
https://doaj.org/article/69915f806f04419f9a5b9cce74f6af71
Autor:
Magdalena Kowalewicz-Kulbat, Krzysztof T. Krawczyk, Izabela Szulc-Kielbik, Sebastian Rykowski, Marta Denel-Bobrowska, Agnieszka B. Olejniczak, Camille Locht, Magdalena Klink
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Ovarian cancer is one of the most frequent and deadly gynaecological cancers, often resistant to platinum-based chemotherapy, the current standard of care. Halophilic microorganisms have been shown to produce a large variety of me
Externí odkaz:
https://doaj.org/article/41e508dc2a9341a78131de936959a070
Autor:
Carla Sardo, Giulia Auriemma, Carmela Mazzacano, Claudia Conte, Virgilio Piccolo, Tania Ciaglia, Marta Denel-Bobrowska, Agnieszka B. Olejniczak, Donatella Fiore, Maria Chiara Proto, Patrizia Gazzerro, Rita Patrizia Aquino
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 971 (2024)
In this study, the structural attributes of nanoparticles obtained by a renewable and non-immunogenic “inulinated” analog of the “pegylated” PLA (PEG-PLA) were examined, together with the potential of these novel nanocarriers in delivering po
Externí odkaz:
https://doaj.org/article/1cc66af718814ce99ed1f1a5c0df29af
Autor:
Sebastian Rykowski, Dorota Gurda-Woźna, Agnieszka Fedoruk-Wyszomirska, Marta Orlicka-Płocka, Aleksandra Kowalczyk, Paweł Stączek, Marta Denel-Bobrowska, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Eliza Wyszko, Agnieszka B. Olejniczak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The synthesis of carborane-1,8-naphthalimide conjugates and evaluation of their DNA-binding ability and anticancer activity were performed. A series of 4-carboranyl-3-nitro-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, were synthesi
Externí odkaz:
https://doaj.org/article/da14e44f868943c69fa7db724c26232b
Autor:
Zbigniew J. Leśnikowski, Filip Ekholm, Narayan S. Hosmane, Martin Kellert, Eiji Matsuura, Hiroyuki Nakamura, Agnieszka B. Olejniczak, Luigi Panza, Louis M. Rendina, Wolfgang A. G. Sauerwein
Publikováno v:
Cells, Vol 13, Iss 10, p 798 (2024)
Given the renewed interest in boron neutron capture therapy (BNCT) and the intensified search for improved boron carriers, as well as the difficulties of coherently comparing the carriers described so far, it seems necessary to define a basic set of
Externí odkaz:
https://doaj.org/article/0e07640c441e49af9a31ec4dbb5ca04f
Autor:
Franz Steppeler, Dominika Iwan, Radosław Gaida, Marta Denel-Bobrowska, Agnieszka B. Olejniczak, Elżbieta Wojaczyńska
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114908- (2023)
2-Azabicycloalkanes: 2-azabicyclo[2.2.1]heptane and 2-azabicyclo[3.2.1]octane were used as a chiral platform for the construction of a set of 1,2,3-triazole, thiourea, and ebselen derivatives. Cytotoxicity and antiviral activity studies revealed the
Externí odkaz:
https://doaj.org/article/ba1bb7d855ee474982e6c4a20a854911
Autor:
Dominika Iwan, Karolina Kamińska, Marta Denel-Bobrowska, Agnieszka B. Olejniczak, Elżbieta Wojaczyńska
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113473- (2022)
Chiral sulfonamides with aromatic fragments are important chemical building blocks found widely in many natural products, catalysts, and molecules of biological importance. In this report, we describe the efficient synthesis of a series of chiral sul
Externí odkaz:
https://doaj.org/article/2fc2d458a1774ea59b6ad2e1308afe14
Autor:
Grzegorz Mlostoń, Mateusz Kowalczyk, Małgorzata Celeda, Marcin Jasiński, Marta Denel-Bobrowska, Agnieszka B. Olejniczak
Publikováno v:
Molecules, Vol 27, Iss 11, p 3524 (2022)
Starting with fluorinated benzylamines, a series of 2-unsubstituted imidazole N-oxides was prepared and subsequently deoxygenated in order to prepare the corresponding imidazoles. The latter were treated with benzyl halides yielding imidazolium salts
Externí odkaz:
https://doaj.org/article/f70b7cc0dfe3487db15412bddaab23dd
Autor:
Sebastian Rykowski, Dorota Gurda-Woźna, Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Małgorzata Giel-Pietraszuk, Eliza Wyszko, Aleksandra Kowalczyk, Paweł Stączek, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Agnieszka B. Olejniczak
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4598 (2022)
In the present study, we continue our work related to the synthesis of 1,8-naphthalimide and carborane conjugates and the investigation of their anticancer activity and DNA-binding ability. For this purpose, a series of 4-carboranyl-1,8-naphthalimide
Externí odkaz:
https://doaj.org/article/db5721b441274939bf04f71e31ea8206
Autor:
Sebastian Rykowski, Dorota Gurda-Woźna, Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Małgorzata Giel-Pietraszuk, Eliza Wyszko, Aleksandra Kowalczyk, Paweł Stączek, Andrzej Bak, Agnieszka Kiliszek, Wojciech Rypniewski, Agnieszka B. Olejniczak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2772 (2021)
We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and amidation reactions and investigated their in vitro effects on cytotoxicity, cell death, cell
Externí odkaz:
https://doaj.org/article/0b68f301865e412baf38aa0197ca4f79