Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Agnieszka A, Zurek"'
Autor:
Jieying Yu, Dian-Shi Wang, Robert P. Bonin, Antonello Penna, Ali Alavian-Ghavanini, Agnieszka A. Zurek, Gail Rauw, Glen B. Baker, Beverley A. Orser
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 203-213 (2019)
Background: Gabapentin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Its anticonvulsant, analgesic and anxiolytic properties suggest that it increases GABAergic inhibition; however, the molecular basis for the
Externí odkaz:
https://doaj.org/article/43c28ecae67b4c3abf95fe5bc1cb2ced
Publikováno v:
Mobile Web and Intelligent Information Systems ISBN: 9783031143908
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3f5b10470e57e4a906659d16bf719c
https://doi.org/10.1007/978-3-031-14391-5_16
https://doi.org/10.1007/978-3-031-14391-5_16
Autor:
Dian-Shi Wang, Agnieszka A. Zurek, Irene Lecker, Jieying Yu, Armen M. Abramian, Sinziana Avramescu, Paul A. Davies, Stephen J. Moss, Wei-Yang Lu, Beverley A. Orser
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 488-496 (2012)
Systemic inflammation causes learning and memory deficits through mechanisms that remain poorly understood. Here, we studied the pathogenesis of memory loss associated with inflammation and found that we could reverse memory deficits by pharmacologic
Externí odkaz:
https://doaj.org/article/1ebcc842bc7d408ba3898da64e571c56
Autor:
Ali Alavian-Ghavanini, Glen B. Baker, Antonello Penna, Beverley A. Orser, Gail Rauw, Jieying Yu, Dian-Shi Wang, Agnieszka A. Zurek, Robert P. Bonin
Publikováno v:
EBioMedicine. 42:203-213
Background Gabapentin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Its anticonvulsant, analgesic and anxiolytic properties suggest that it increases GABAergic inhibition; however, the molecular basis for thes
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58679 (2013)
Changes in the expression of γ-aminobutyric acid type A (GABAA) receptors can either drive or mediate homeostatic alterations in neuronal excitability. A homeostatic relationship between α5 subunit-containing GABAA (α5GABAA) receptors that generat
Externí odkaz:
https://doaj.org/article/79e40da878dd4b64b5dbd6133ff8fa70
Autor:
Louis-Etienne Lorenzo, Agnieszka A. Zurek, Jimena Perez-Sanchez, Irene Lecker, Robert P. Bonin, Erica M. Bridgwater, Charalampos Labrakakis, Yves De Koninck, Beverley A. Orser
Publikováno v:
Journal of Neuroscience Research. 95:1307-1318
Neuronal inhibition mediated by GABAA receptors constrains nociceptive processing in the spinal cord, and loss of GABAergic inhibition can produce allodynia and hyperalgesia. Extrasynaptic α5 subunit-containing GABAA receptors (α5GABAA Rs) generate
Autor:
Beverley A. Orser, Zeenia Aga, Amy J. Ramsey, Susan Walker, Agnieszka A. Zurek, Stephen W.P. Kemp, Stephen W. Scherer, Etienne Sibille, Marija Milenkovic
Publikováno v:
Annals of Clinical and Translational Neurology
The prevalence of autism spectrum disorders (ASDs), which affect over 1% of the population, has increased twofold in recent years. Reduced expression of GABAA receptors has been observed in postmortem brain tissue and neuroimaging of individuals with
Autor:
Tamás Füzesi, Agnieszka A. Zurek, Núria Daviu, Toni-Lee Sterley, David Rosenegger, Neilen P. Rasiah, Jaideep S. Bains, Dinara V. Baimoukhametova
Publikováno v:
Nature neuroscience. 21(3)
Stress can trigger enduring changes in neural circuits and synapses. The behavioral and hormonal consequences of stress can also be transmitted to others, but whether this transmitted stress has similar effects on synapses is not known. We found that
Autor:
Paula A. Zamudio-Bulcock, Julie C. Everett, Jieying Yu, Beverley A. Orser, Samantha L. Blomquist, Russell A. Morton, William Vollmer, C. Fernando Valenzuela, Cyndel C. Vollmer, Marvin R. Diaz, Agnieszka A. Zurek
Publikováno v:
Neuropharmacology. 79:262-274
Exposure to ethanol (EtOH) during fetal development can lead to long-lasting alterations, including deficits in fine motor skills and motor learning. Studies suggest that these are, in part, a consequence of cerebellar damage. Cerebellar granule neur
Autor:
Jimena, Perez-Sanchez, Louis-Etienne, Lorenzo, Irene, Lecker, Agnieszka A, Zurek, Charalampos, Labrakakis, Erica M, Bridgwater, Beverley A, Orser, Yves, De Koninck, Robert P, Bonin
Publikováno v:
Journal of neuroscience research. 95(6)
Neuronal inhibition mediated by GABA