Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Agnieszka, Wozniak"'
Autor:
Lore De Cock, Flavia Paternostro, Ulla Vanleeuw, Karo Wyns, Annouschka Laenen, Che-Jui Lee, Raf Sciot, Agnieszka Wozniak, Patrick Schöffski
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102057- (2024)
Background: Synovial sarcoma (SynSa) is one of the most common translocation-related soft tissue sarcomas. Patients with metastatic SynSa have limited treatment options and a very poor prognosis. Several novel experimental therapies are currently bei
Externí odkaz:
https://doaj.org/article/1849db8fb1904ffe95310ec132df2b55
Autor:
Yana Beulque, Lisa Kinget, Eduard Roussel, Sajedeh Mobaraki, Annouschka Laenen, Philip R. Debruyne, Yannick Van Herck, Marcella Baldewijns, Agnieszka Wozniak, Abhishek D. Garg, Jessica Zucman-Rossi, Gabrielle Couchy, Maarten Albersen, Liesbeth De Wever, Lorenz Haaker, Benoit Beuselinck
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: This study aims to evaluate neutrophil-to-eosinophil ratio (NER) as a prognostic and/or predictive biomarker in metastatic clear cell renal cell carcinoma (m-ccRCC) treated with nivolumab or ipilimumab/nivolumab. Patients/mat
Externí odkaz:
https://doaj.org/article/abbe9ce3cee1430289a9bbcf22379019
Autor:
Szymon Macioszek, Danuta Dudzik, Rafał Bartoszewski, Tomasz Stokowy, Diether Lambrechts, Bram Boeckx, Agnieszka Wozniak, Patrick Schöffski, Michał J. Markuszewski
Publikováno v:
Translational Oncology, Vol 30, Iss , Pp 101632- (2023)
Background: Although imatinib is a well-established first-line drug for treating a vast majority of gastrointestinal stromal tumours (GIST), GISTs acquire secondary resistance during therapy. Multi-omics approaches provide an integrated perspective t
Externí odkaz:
https://doaj.org/article/45e412c3a749489d854a7e0c278adf19
Autor:
Jasmien Cornillie, Agnieszka Wozniak, Britt Van Renterghem, Nathalie Van Winkel, Jasmien Wellens, Yemarshet K. Gebreyohannes, Maria Debiec-Rychter, Raf Sciot, Daphne Hompes, Patrick Schöffski
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Soft tissue sarcoma (STS) comprises a family of rare, heterogeneous tumors of mesenchymal origin. Single-agent doxorubicin remains the first-line standard-of-care treatment for advanced and inoperable STS, but response rates are o
Externí odkaz:
https://doaj.org/article/04a447b35404461fae43948d5d350cc7
Autor:
Samuel V. Rasmussen, Agnieszka Wozniak, Melvin Lathara, Joshua M. Goldenberg, Benjamin M. Samudio, Lissett R. Bickford, Kiyo Nagamori, Hollis Wright, Andrew D. Woods, Shefali Chauhan, Che-Jui Lee, Erin R. Rudzinski, Michael K. Swift, Tadashi Kondo, David E. Fisher, Evgeny Imyanitov, Isidro Machado, Antonio Llombart-Bosch, Irene L. Andrulis, Nalan Gokgoz, Jay Wunder, Hiroshi Mirotaki, Takuro Nakamura, Ganapati Srinivasa, Khin Thway, Robin L. Jones, Paul H. Huang, Noah E. Berlow, Patrick Schöffski, Charles Keller
Publikováno v:
British Journal of Cancer. 128:1941-1954
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e02c2d2a381257b647d3ba4b83b3d345
https://doi.org/10.1038/s41416-023-02222-0
https://doi.org/10.1038/s41416-023-02222-0
Autor:
Che-Jui Lee, Agnieszka Wozniak, Thomas Van Cann, Iris Timmermans, Jasmien Wellens, Ulla Vanleeuw, Inge H. Briaire-de Bruijn, Christian Britschgi, Judith V. M. G. Bovée, Inti Zlobec, Raf Sciot, Patrick Schöffski
Publikováno v:
Sarcoma, Vol 2021 (2021)
Soft tissue sarcoma (STS) is a heterogeneous family of rare mesenchymal tumors, characterized by histopathological and molecular diversity. Tissue microarray (TMA) is a tool that allows performing research in orphan diseases in a more efficient and c
Externí odkaz:
https://doaj.org/article/75dc8183195b42d8933554d4f066ec96
Autor:
Patrick Schöffski, Yemarshet Gebreyohannes, Thomas Van Looy, Paul Manley, Joseph D. Growney, Matthew Squires, Agnieszka Wozniak
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1135 (2022)
Advanced gastrointestinal stromal tumors (GIST) are typically treated with tyrosine kinase inhibitors, and imatinib is the most commonly used standard of care in first line treatments. The use of this and other tyrosine kinase inhibitors is associate
Externí odkaz:
https://doaj.org/article/484920ba396f47a9b8dfc3ffc6188718
Autor:
Britt Van Renterghem, Agnieszka Wozniak, Ludovica Tarantola, Andrea Casazza, Jasmien Wellens, Madita Nysen, Ulla Vanleeuw, Che-Jui Lee, Geert Reyns, Raf Sciot, Nele Kindt, Patrick Schöffski
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 862 (2022)
Despite poor response rates and dose-limiting cardiotoxicity, doxorubicin (doxo) remains the standard-of-care for patients with advanced soft tissue sarcoma. We evaluated the efficacy of two tetrapeptidic doxo prodrugs (PhAc-ALGP-Dox or CBR-049 and C
Externí odkaz:
https://doaj.org/article/a512cdb2502b47388dd8c6090096ed70
Autor:
Yannick Wang, Agnieszka Wozniak, Jasmien Wellens, Yemarshet K. Gebreyohannes, Maria Jose Guillén, Pablo M. Avilés, Maria Debiec-Rychter, Raf Sciot, Patrick Schöffski
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100832- (2020)
The majority of patients with gastrointestinal stromal tumors (GIST) eventually become resistant with time due to secondary mutations in the driver receptor tyrosine kinase. Novel treatments that do not target these receptors may therefore be prefera
Externí odkaz:
https://doaj.org/article/5bd45724a5e8427981d92dd9f2e59aa0
Autor:
Annelies Verbiest, Vincent Van Hoef, Cristina Rodriguez-Antona, Jesús García-Donas, Osvaldo Graña-Castro, Maarten Albersen, Marcella Baldewijns, Annouschka Laenen, Eduard Roussel, Patrick Schöffski, Agnieszka Wozniak, Stefano Caruso, Gabrielle Couchy, Jessica Zucman-Rossi, Benoit Beuselinck
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238809 (2020)
Clear-cell renal cell carcinomas (ccRCC) can be divided into four transcriptomic subtypes, two of which have a favorable and two an unfavorable prognosis. To assess mechanisms driving these subtypes, we investigated their miRNA expression patterns. m
Externí odkaz:
https://doaj.org/article/30baa197e6f241efb27d73daebcccfed