Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Agneta Wijkström"'
Autor:
Viveka Hillegaart, Agneta Wijkström, Sven Ahlenius, Evalena Ericson, Lennart Florvall, Patricia Jimenez
Publikováno v:
European Journal of Pharmacology. 394:247-253
Behavioral and biochemical techniques were used to compare the in vivo intrinsic efficacy of two new 2-(4-aminophenyl)-N, N-dipropylethylamine dopamine D(2) receptor agonists, 2-(4-amino-3-trifluoromethylphenyl)-N-N-dipropyl-ethylamine (NBF-203) and
Publikováno v:
European Journal of Medicinal Chemistry. 31:133-142
Summary A series of 2-(4-aminophenyl)- N,N -dipropylethylamine derivatives were synthesized and tested for in vivo intrinsic activity at brain dopamine receptors in the rat. Differences in the sensitivity of dopamine receptors pre- and post-synaptica
Publikováno v:
Pharmacology & Toxicology. 72:398-406
The effects of the 5-HT1A receptor agonists 8-OH-DPAT (0.15-2.5 mumol kg-1 subcutaneously), flesinoxan (0.6-10.0 mumol kg-1 subcutaneously) and buspirone (1.9-30.0 mumol kg-1 subcutaneously) on spontaneous motor activity in male Sprague-Dawley rats w
Publikováno v:
European Journal of Pharmacology. 200:259-266
The 5-HT 1A receptor agonists flesinoxan (0.2–3.2 mg kg −1 s.c.) and 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) (0.025–0.4 mg kg −1 s.c.) produced (1) a dose-dependent facilitation of male rat ejaculatory behavior and (2) characterist
Publikováno v:
Pharmacology & Toxicology. 68:302-309
Male Sprague-Dawley rats were treated with the dopamine (DA) D2 receptor blocking agent raclopride 0.5 or 8.0 mg kg−1 subcutaneously (1.0 and 16.0 μmol kg−1, respectively), twice daily for 21 days. The animals treated with raclopride gained weig
Publikováno v:
Journal of Pharmacy and Pharmacology. 42:285-288
The administration of the 5-HT1A agonist 8-OH-DPAT (0.8 μmol kg−1 s.c. — 40 min) produced an increase in dopamine (DA) turnover, estimated by the quotient (DOPAC + HVA) DA−1, in the ventral striatum of the rat. No statistically significant eff
Publikováno v:
Neuroscience Letters. 126:57-59
The rate of brain monoamine synthesis was estimated in the rat by measuring the accumulation of dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) following inhibition of cerebral aromatic amino acid decarboxylase by NSD-1015 (475 μmol/kg
Publikováno v:
The Journal of pharmacy and pharmacology. 45(3)
Male Sprague-Dawley rats were treated subcutaneously with reserpine (5 mg kg−1, — 18 h) and with the aromatic amino acid decarboxylase inhibitor, NSD-1015 (3-hydroxybenzylhydrazine) (100 mg kg−1 -30 min). Remoxipride 0 -8, 3 -2 or 12 -8 mg kg
Publikováno v:
European Neuropsychopharmacology. 3:390
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 339:551-556
Regional dopamine synthesis in the rat striatum was estimated by measuring DOPA accumulation following inhibition of cerebral aromatic L-amino acid decarboxylase by means of NSD-1015, 100 mg kg-1 intraperitoneally. In animals treated with reserpine,