Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Agneta Öberg"'
Autor:
Laura Leykam, Karin M.E. Forsberg, Ulrika Nordström, Karin Hjertkvist, Agneta Öberg, Eva Jonsson, Peter M. Andersen, Stefan L. Marklund, Per Zetterström
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106718- (2024)
Mutations in superoxide dismutase-1 (SOD1) are a cause of hereditary amyotrophic lateral sclerosis (ALS) through a gain-of-function mechanism involving unfolded mutant SOD1. Intrathecal gene therapy using the antisense-oligo-nucleotide drug tofersen
Externí odkaz:
https://doaj.org/article/5e9c3ec2a9c248b1b182960dfbe032f1
Autor:
Göran Wikander, Peter Nilsson, Per-Ingvar Ohlsson, Lars Forsgren, Agneta Öberg, Peter M. Andersen, Stefan L. Marklund
Publikováno v:
Journal of Neurochemistry. 69:675-681
In some families with amyotrophic lateral sclerosis (ALS), the disease is linked to mutations in the gene encoding CuZn-superoxide dismutase. The mutant CuZn-superoxide dismutases appear to cause motor neuron degeneration by a toxic property, suggest
Autor:
Ulf Näslund, Stefan L. Marklund, Agneta Öberg, Sebastian Reiz, Sören Häggmark, Göran Johansson
Publikováno v:
Journal of Molecular and Cellular Cardiology. 18:1077-1084
We investigated if superoxide dismutase and catalase could reduce myocardial infarct size in an open chest occlusion-reperfusion model. Thirty pigs were used for the experiment. The left anterior descending artery was ligated for 60 min followed by a