Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Agneta, Simionescu"'
Autor:
Bo Wang, Leslie N. Sierad, Jeremy J. Mercuri, Agneta Simionescu, Dan T. Simionescu, Lakiesha N. Williams, Ryan Vela, Pietro Bajona, Matthias Peltz, Sharan Ramaswamy, Yi Hong, Jun Liao
Publikováno v:
Engineered Regeneration, Vol 3, Iss 4, Pp 374-386 (2022)
Mitral valve (MV) tissue engineering is still in its early stage, and one major challenge in MV tissue engineering is to identify appropriate scaffold materials. With the potential of acellular MV scaffolds being demonstrated recently, it is importan
Externí odkaz:
https://doaj.org/article/ae1bf0e23b114f31ac26e92826cbe042
Autor:
Dan Simionescu, Nishanth Tharayil, Elizabeth Leonard, Wenda Carlyle, Alex Schwarz, Kelvin Ning, Christopher Carsten, Juan Carlos Carrillo Garcia, Alexander Carter, Collin Owens, Agneta Simionescu
Publikováno v:
Bioengineering, Vol 10, Iss 8, p 936 (2023)
Pentagalloyl glucose (PGG) is currently being investigated as a non-surgical treatment for abdominal aortic aneurysms (AAAs); however, the molecular mechanisms of action of PGG on the AAA matrix components and the intra-luminal thrombus (ILT) still n
Externí odkaz:
https://doaj.org/article/749b85ecce224ee3a316826c704b39d8
Publikováno v:
Romanian Journal of Cardiology, Vol 31, Iss 3, Pp 501-510 (2021)
Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement. Regenerative Medicine and T
Externí odkaz:
https://doaj.org/article/a8d3a907ad8a4d649cddf5ad2e5e703a
Autor:
Ionela MOVILEANU, Dan Octavian NISTOR, Leslie SIERAD, Klara BRINZANIUC, Codrut OPRITA, Marius Mihai HARPA, Terezia PREDA, Ovidiu COTOI, Hussam AL HUSSEIN, Hamida AL HUSSEIN, Alexandru CHERTES, Horatiu SUCIU, Agneta SIMIONESCU, Dan SIMIONESCU
Publikováno v:
Romanian Journal of Cardiology, Vol 31, Iss 3, Pp 555-563 (2021)
The inherent limitations of current heart valve substitutes create the premise for the Tissue Engineered Heart Valve (TEHV), considered the perfect substitute. We aimed to compare in vitro hemodynamic performances of our TEHV, the conventional prosth
Externí odkaz:
https://doaj.org/article/b11565e6e826474586df3d3bd2a29cf2
Autor:
Sergiu Cecoltan, Letitia Ciortan, Razvan D. Macarie, Mihaela Vadana, Andreea C. Mihaila, Monica Tucureanu, Mihaela-Loredana Vlad, Ionel Droc, Mihaela Gherghiceanu, Agneta Simionescu, Dan Teodor Simionescu, Elena Butoi, Ileana Manduteanu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Valvular endothelial cells (VEC) have key roles in maintaining valvular integrity and homeostasis, and dysfunctional VEC are the initiators and major contributors to aortic valve disease in diabetes. Previous studies have shown that HG st
Externí odkaz:
https://doaj.org/article/3e40bb1634e842aab75c613b393ecb72
Autor:
Ionela Movileanu, Marius Harpa, Hussam Al Hussein, Lucian Harceaga, Alexandru Chertes, Hamida Al Hussein, Georg Lutter, Thomas Puehler, Terezia Preda, Carmen Sircuta, Ovidiu Cotoi, Dan Nistor, Adrian Man, Bogdan Cordos, Radu Deac, Horatiu Suciu, Klara Brinzaniuc, Megan Casco, Leslie Sierad, Margarita Bruce, Dan Simionescu, Agneta Simionescu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Introduction: Pediatric patients with cardiac congenital diseases require heart valve implants that can grow with their natural somatic increase in size. Current artificial valves perform poorly in children and cannot grow; thus, living-tissue-engine
Externí odkaz:
https://doaj.org/article/3941edf86721482fabef76e1788269e0
Autor:
Alexandru Filippi, Alina Constantin, Nicoleta Alexandru, Cristina Ana Mocanu, Mihaela Loredana Vlad, Ioana Madalina Fenyo, Agneta Simionescu, Dan Teodor Simionescu, Ileana Manduteanu, Adriana Georgescu
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1077 (2022)
The number and function of endothelial progenitor cells (EPCs) are reduced in diabetes, contributing to deteriorated vascular repair and the occurrence of cardiovascular complications. Here, we present the results of treating early diabetic dyslipide
Externí odkaz:
https://doaj.org/article/43fde9ec37ff44a99e1ccb6c12d7926f
Autor:
Alexandru Filippi, Alina Constantin, Nicoleta Alexandru, Geanina Voicu, Cristina Ana Constantinescu, Daniela Rebleanu, Madalina Fenyo, Dan Simionescu, Agneta Simionescu, Ileana Manduteanu, Adriana Georgescu
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Diabetes reduces the number and induces dysfunction in circulating endothelial progenitor cells (EPCs) by mechanisms that are still uncovered. This study aims to evaluate the number, viability, phenotype, and function of EPCs in dyslipidemic mice wit
Externí odkaz:
https://doaj.org/article/5dd1edf56e3e479bb6edb3c032e323b6
Publikováno v:
Journal of Cellular and Molecular Medicine
Valve disease and particularly calcific aortic valve disease (CAVD) and diabetes (DM) are progressive diseases constituting a global health burden for all aging societies (Progress in Cardiovascular Diseases. 2014;56(6):565: Circulation Research. 202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40ffe519ed5fc0e8472048b2cea3b75
https://doi.org/10.1111/jcmm.16937
https://doi.org/10.1111/jcmm.16937
Publikováno v:
Romanian Journal of Cardiology, Vol 31, Iss 3, Pp 501-510 (2021)
Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement. Regenerative Medicine and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c2e8bdafa87555e566720418e3f988
https://www.romanianjournalcardiology.ro/wp-content/uploads/2021/09/RRC_art-2.pdf
https://www.romanianjournalcardiology.ro/wp-content/uploads/2021/09/RRC_art-2.pdf