Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Agnese Serafini"'
Autor:
Riccardo Manganelli, Laura Cioetto-Mazzabò, Greta Segafreddo, Francesca Boldrin, Davide Sorze, Marta Conflitti, Agnese Serafini, Roberta Provvedi
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The Extracellular function (ECF) sigma factor SigE is one of the best characterized out of the 13 sigma factors encoded in the Mycobacterium tuberculosis chromosome. SigE is required for blocking phagosome maturation and full virulence in both mice a
Externí odkaz:
https://doaj.org/article/1302d970cc554718848eba18398f94d5
Autor:
Aleksandra Agapova, Agnese Serafini, Michael Petridis, Debbie M Hunt, Acely Garza-Garcia, Charles D Sohaskey, Luiz Pedro Sório de Carvalho
Publikováno v:
eLife, Vol 8 (2019)
Bacterial metabolism is fundamental to survival and pathogenesis. We explore how Mycobacterium tuberculosis utilises amino acids as nitrogen sources, using a combination of bacterial physiology and stable isotope tracing coupled to mass spectrometry
Externí odkaz:
https://doaj.org/article/138db50f2e024e80b6855cc738946573
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/af2369ff377c48f2816744c3a95d0e66
The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78351 (2013)
ESX-3 is one of the five type VII secretion systems encoded by the Mycobacterium tuberculosis genome. We recently showed the essentiality of ESX-3 for M. tuberculosis viability and proposed its involvement in iron and zinc metabolism. In this study w
Externí odkaz:
https://doaj.org/article/b23dea5938134925a0c45ce9b9e34318
Autor:
Giacomo Baruzzo, Agnese Serafini, Francesca Finotello, Tiziana Sanavia, Laura Cioetto-Mazzabò, Francesca Boldrin, Enrico Lavezzo, Luisa Barzon, Stefano Toppo, Roberta Provvedi, Riccardo Manganelli, Barbara Di Camillo
Publikováno v:
Microbiology Spectrum. 11
Mycobacterium tuberculosis can enter a dormant state enabling it to establish latent infections and to become tolerant to antibacterial drugs. Dormant bacteria’s physiology and the mechanism(s) used by bacteria to enter dormancy during infection ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20682847e5b7323ee549de4b98c7a073
https://doi.org/10.1128/spectrum.02944-22
https://doi.org/10.1128/spectrum.02944-22
Autor:
Agnese Serafini
Publikováno v:
Microbiology (Reading, England). 167(6)
Bacterial nutrition is a fundamental aspect of pathogenesis. While the host environment is in principle nutrient-rich, hosts have evolved strategies to interfere with nutrient acquisition by pathogens. In turn, pathogens have developed mechanisms to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b1f6aacb0a546ef9588709720f7570
https://pubmed.ncbi.nlm.nih.gov/34080971
https://pubmed.ncbi.nlm.nih.gov/34080971
Autor:
Luiz Pedro S. de Carvalho, Steven Howell, Mercedes Monteleone, Stuart Horswell, Brian C. VanderVen, Warwick J. Britton, Ambrosius P. Snijders, Agnese Serafini, Acely Garza-Garcia, Lendl Tan, Minh-Duy Phan, Mark A. Schembri, Maximiliano G. Gutierrez, Christine R Montague, Nicholas P. West, Deborah M. Hunt, Daniel J. Greenwood
Publikováno v:
Molecular Microbiology
Summary Bacterial nutrition is an essential aspect of host–pathogen interaction. For the intracellular pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis in humans, fatty acids derived from lipid droplets are considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164641ab7aad65dcd47e554e5658fbce
https://doi.org/10.1111/mmi.14362
https://doi.org/10.1111/mmi.14362
Autor:
Ana Pavić, Vincent L. G. Postis, Agnese Serafini, Mark Bartlam, Martin J. McPhillie, Alexandra O. M. Holmes, Yingying Wang, Luiz Pedro S. de Carvalho, Acely Garza-Garcia, Adrian Goldman, Yurui Ji
Publikováno v:
Journal of Bacteriology. 203
Characterizing the mycobacterial transporters involved in the uptake and/or catabolism of host-derived nutrients required by mycobacteria may identify novel drug targets against tuberculosis. Here, we identify and characterize a member of the amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49b9ac0c69d66b7b08a65e1d7a031fb
https://doi.org/10.1128/jb.00642-20
https://doi.org/10.1128/jb.00642-20
Autor:
Ana, Pavić, Yurui, Ji, Agnese, Serafini, Acely, Garza-Garcia, Martin J, McPhillie, Alexandra O M, Holmes, Luiz Pedro Sório, de Carvalho, Yingying, Wang, Mark, Bartlam, Adrian, Goldman, Vincent L G, Postis
Publikováno v:
Journal of Bacteriology
The spread of multidrug-resistant tuberculosis increases its global health impact in humans. As there is transmission both to and from animals, the spread of the disease also increases its effects in a broad range of animal species.
Characterizi
Characterizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4aa68d0cd0431f1bd1e24ffceeeda2a
https://pubmed.ncbi.nlm.nih.gov/33288625
https://pubmed.ncbi.nlm.nih.gov/33288625
Autor:
Saber Anoosheh, Laura Cioetto Mazzabò, Francesca Boldrin, Agnese Serafini, Roberta Provvedi, Riccardo Manganelli, Giorgio Palù
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-6 (2019)
Tightly regulated gene expression systems are powerful tools to study essential genes and characterize potential drug targets. In a past work we reported the construction of a very stringent and versatile repressible promoter system for Mycobacterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa87ecc0148007ec28ef995f93121f9f
https://doi.org/10.1038/s41598-019-42319-2
https://doi.org/10.1038/s41598-019-42319-2