Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Agnese Abate"'
Autor:
Giulio Dondio, Saverio Minucci, Roberto Boggio, Giacomo Carenzi, Agnese Abate, Mario Varasi, Marco Giulio Rozio, Ciro Mercurio, Roberto Dal Zuffo, Chiara Bigogno, Maria Carmela Fulco, Florian Thaler, Tiziana Cataudella, Antonello Mai
Publikováno v:
Journal of Medicinal Chemistry. 54:3051-3064
New spiro[chromane-2,4'-piperidine] and spiro[benzofuran-2,4'-piperidine] hydroxamic acid derivatives as HDAC inhibitors have been identified by combining privileged structures with a hydroxamic acid moiety as zinc binding group. The compounds were e
Publikováno v:
Tetrahedron: asymmetry
18 (2007): 1145–1153. doi:10.1016/j.tetasy.2007.04.022
info:cnr-pdr/source/autori:Abate A., Brenna E., Fuganti C., Malpezzi L., Serra S./titolo:The enantiomers of Iralia (R): preparation and odour evaluation/doi:10.1016%2Fj.tetasy.2007.04.022/rivista:Tetrahedron: asymmetry (Print)/anno:2007/pagina_da:1145/pagina_a:1153/intervallo_pagine:1145–1153/volume:18
18 (2007): 1145–1153. doi:10.1016/j.tetasy.2007.04.022
info:cnr-pdr/source/autori:Abate A., Brenna E., Fuganti C., Malpezzi L., Serra S./titolo:The enantiomers of Iralia (R): preparation and odour evaluation/doi:10.1016%2Fj.tetasy.2007.04.022/rivista:Tetrahedron: asymmetry (Print)/anno:2007/pagina_da:1145/pagina_a:1153/intervallo_pagine:1145–1153/volume:18
The enantiomers of methyl ionones 1 and 2 were prepared by an enzyme-catalysed approach. Their odour properties were evaluated by skilful perfumers.
Autor:
Raffaella Amici, Ciro Mercurio, Andrea Colombo, Maria Carmela Fulco, Luca Sartori, Florian Thaler, Giulio Dondio, Saverio Minucci, Stefania Gagliardi, Roberto Boggio, Loris Moretti, Giacomo Carenzi, Agnese Abate, Mario Varasi
Publikováno v:
European journal of medicinal chemistry. 108
In the last decades, inhibitors of histone deacetylases (HDAC) have become an important class of anti-cancer agents. In a previous study we described the synthesis of spiro[chromane-2,4'-piperidine]hydroxamic acid derivatives able to inhibit histone
Autor:
Maurizio Allievi, Elisabetta Brenna, Claudio Fuganti, Stefano Serra, Francesco G. Gatti, Agnese Abate
Publikováno v:
Helvetica chimica acta 89 (2006): 177–189. doi:10.1002/hlca.200690020
info:cnr-pdr/source/autori:Abate A., Allievi M., Brenna E., Fuganti C., Gatti F.G., Serra S./titolo:Enzymatic approach to and odor description of the twelve enantiomerically pure isomers of Pelargene (R)/doi:10.1002%2Fhlca.200690020/rivista:Helvetica chimica acta/anno:2006/pagina_da:177/pagina_a:189/intervallo_pagine:177–189/volume:89
info:cnr-pdr/source/autori:Abate A., Allievi M., Brenna E., Fuganti C., Gatti F.G., Serra S./titolo:Enzymatic approach to and odor description of the twelve enantiomerically pure isomers of Pelargene (R)/doi:10.1002%2Fhlca.200690020/rivista:Helvetica chimica acta/anno:2006/pagina_da:177/pagina_a:189/intervallo_pagine:177–189/volume:89
Pelargene (R) is a commercial fragrance sold as a mixture of three regioisomeric pyran derivatives (1-3). The enantiomers of each of the two possible diastereoisomers of 1-3 were prepared by means of a biocatalyzed approach, and the odor properties o
Publikováno v:
Synthesis. 2005:2798-2809
Two seco-theaspiranes with pronounced blackcurrant notes, 2-tert-butyl-5-methyl-2-propyl-2,5-dihydrofuran (7) and 2-tert-butyl-5-methyl-2-propyltetrahydrofuran (8), were synthesized by a synthetic sequence consisting of Grignard reaction, Lindlar hyd
Publikováno v:
Journal of molecular catalysis. B, Enzymatic
32 (2004): 33–51. doi:10.1016/j.molcatb.2004.09.008
info:cnr-pdr/source/autori:Abate Agnese, Brenna Elisabetta, Fuganti Claudio, Gatti Francesco G., Serra Stefano/titolo:Lipase-catalysed preparation of enantiomerically enriched odorants/doi:10.1016%2Fj.molcatb.2004.09.008/rivista:Journal of molecular catalysis. B, Enzymatic (Print)/anno:2004/pagina_da:33/pagina_a:51/intervallo_pagine:33–51/volume:32
32 (2004): 33–51. doi:10.1016/j.molcatb.2004.09.008
info:cnr-pdr/source/autori:Abate Agnese, Brenna Elisabetta, Fuganti Claudio, Gatti Francesco G., Serra Stefano/titolo:Lipase-catalysed preparation of enantiomerically enriched odorants/doi:10.1016%2Fj.molcatb.2004.09.008/rivista:Journal of molecular catalysis. B, Enzymatic (Print)/anno:2004/pagina_da:33/pagina_a:51/intervallo_pagine:33–51/volume:32
This review describes the use of lipase-mediated reactions to prepare enantiomerically enriched chiral fragrances for the evaluation of the odour properties of single stereoisomers.
Publikováno v:
Flavour and Fragrance Journal. 19:382-393
The enzyme-mediated synthesis of enantiomerically enriched 1,3-dioxane odorants analogous to Floropal® is here described. The complete olfactory evaluation of each sample is also reported. The addition of a single methyl group at C5 of the dioxane r
Autor:
Giovanni Fronza, Stefano Serra, Agnese Abate, Francesco G. Gatti, Enrica Zardoni, Claudio Fuganti, Elisabetta Brenna
Publikováno v:
Helvetica Chimica Acta. 87:765-780
All the enantiomerically enriched stereoisomers of Clarycet ® (1), Florol ® (2), and Rhubafuran ® (3) were prepared by biocatalysis routes. Their absolute configurations were established, and their olfactory properties were fully evaluated.
Autor:
Claudio Fuganti, Elisabetta Brenna, Stefano Serra, Sabrina Ronzani, Agnese Abate, Giovanni Fronza
Publikováno v:
Helvetica chimica acta 86 (2003): 592–606. doi:10.1002/hlca.200390059
info:cnr-pdr/source/autori:Abate Agese, Brenna Elisabetta, Fronza Giovanni, Fuganti Claudio, Ronzani Sabrina, Serra Stefano/titolo:Enzyme-Mediated Preparation of Chiral 1,3-Dioxane Odorants/doi:10.1002%2Fhlca.200390059/rivista:Helvetica chimica acta/anno:2003/pagina_da:592/pagina_a:606/intervallo_pagine:592–606/volume:86
info:cnr-pdr/source/autori:Abate Agese, Brenna Elisabetta, Fronza Giovanni, Fuganti Claudio, Ronzani Sabrina, Serra Stefano/titolo:Enzyme-Mediated Preparation of Chiral 1,3-Dioxane Odorants/doi:10.1002%2Fhlca.200390059/rivista:Helvetica chimica acta/anno:2003/pagina_da:592/pagina_a:606/intervallo_pagine:592–606/volume:86
The enantiomerically enriched diastereoisomers of the chiral 1,3-dioxane odorants Floropal(R) (1) and Magnolan(R) (2) were prepared by an enzyme-mediated approach. Their olfactory properties were evaluated to investigate differences in the odor perce
Publikováno v:
Tetrahedron: Asymmetry. 13:899-904
The two enantiomers of the floral odorant Florhydral® were prepared by enzymatic methods, and their olfactory properties were evaluated. (+)-Florhydral® was found to be much more powerful than the (−)-enantiomer.