Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Agnes Telling"'
Autor:
Amy R Strom, Ronald J Biggs, Edward J Banigan, Xiaotao Wang, Katherine Chiu, Cameron Herman, Jimena Collado, Feng Yue, Joan C Ritland Politz, Leah J Tait, David Scalzo, Agnes Telling, Mark Groudine, Clifford P Brangwynne, John F Marko, Andrew D Stephens
Publikováno v:
eLife, Vol 10 (2021)
Chromatin, which consists of DNA and associated proteins, contains genetic information and is a mechanical component of the nucleus. Heterochromatic histone methylation controls nucleus and chromosome stiffness, but the contribution of heterochromati
Externí odkaz:
https://doaj.org/article/7e515497572943718908128a28128049
Autor:
Joan C. Ritland Politz, Katherine Chiu, Mark Groudine, Feng Yue, Clifford P. Brangwynne, Xiaotao Wang, Andrew D. Stephens, David Scalzo, Ronald J Biggs, Leah J Tait, Edward J. Banigan, Amy R. Strom, John F. Marko, Agnes Telling, Cameron Herman, Jimena Collado
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Chromatin, which consists of DNA and associated proteins, contains genetic information and is a mechanical component of the nucleus. Heterochromatic histone methylation controls nucleus and chromosome stiffness, but the contribution of heterochromati
Autor:
Leah J Tait, Katherine Chiu, John F. Marko, Mark Groudine, Andrew D. Stephens, Edward J. Banigan, Amy R. Strom, Clifford P. Brangwynne, David Scalzo, Feng Yue, Joan C. Ritland Politz, Xiaotao Wang, Jimena Collado, Agnes Telling, Cameron Herman, Ronald J Biggs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e808b8c73a749ef08cf9097acca5c2
https://doi.org/10.7554/elife.63972.sa2
https://doi.org/10.7554/elife.63972.sa2
Publikováno v:
Nucleus
The eukaryotic nucleus is structurally and functionally organized, as reflected in the distribution of its protein and DNA components. The genome itself is segregated into euchromatin and heterochromatin that replicate in a distinct spatio-temporal m
Autor:
Tobias Ragoczy, Jongjoo Lee, Michaël Bender, Agnes Telling, Ann Dean, Mark Groudine, Rachel Byron
Publikováno v:
Blood. 119:3820-3827
The β-globin locus control region (LCR) is necessary for high-level β-globin gene transcription and differentiation-dependent relocation of the β-globin locus from the nuclear periphery to the central nucleoplasm and to foci of hyperphosphorylated
Autor:
Maxim Imakaev, Ido Amit, Peter J. Sabo, Job Dekker, Agnes Telling, Michael O. Dorschner, Nynke L. van Berkum, Louise Williams, Leonid A. Mirny, Mark Groudine, Erez Lieberman Aiden, John A. Stamatoyannopoulos, Andreas Gnirke, Richard Sandstrom, Tobias Ragoczy, Bryan R. Lajoie, Eric S. Lander, Bradley E. Bernstein, Michaël Bender
Publikováno v:
Science. 326:289-293
Chromosomal Mapping The conformation of the genome in the nucleus and contacts between both proximal and distal loci influence gene expression. In order to map genomic contacts, Lieberman-Aiden et al. (p. 289 , see the cover) developed a technique to
Publikováno v:
Chromosome Research. 11:513-525
Recent studies of nuclear organization have shown an apparent correlation between the localization of genes within the interphase nucleus and their transcriptional status. In several instances, actively transcribed gene loci have been found significa
Autor:
Dirk Schübeler, Matthew C. Lorincz, Daniel M. Cimbora, Eric E. Bouhassira, Yong-Quing Feng, Agnes Telling, Mark Groudine
Publikováno v:
Molecular and Cellular Biology. 20:9103-9112
We have developed a strategy to introduce in vitro-methylated DNA into defined chromosomal locations. Using this system, we examined the effects of methylation on transcription, chromatin structure, histone acetylation, and replication timing by targ
Autor:
Ross C. Hardison, Elliot M. Epner, Michaël Bender, Jennie Close, Andreas Reik, Agnes Telling, Mark Groudine, Steven Fiering
Publikováno v:
Blood. 92:4394-4403
The most upstream hypersensitive site (HS) of the β-globin locus control region (LCR) in humans (5′ HS 5) and chickens (5′ HS 4) can act as an insulating element in some gain of function assays and may demarcate a β-globin domain. We have mappe
Autor:
Tariq Enver, Yuan Zhuang, Agnes Telling, Ming Hu, Timothy J. Ley, Mark Groudine, David I. K. Martin, Steven Fiering, Kirsten Robinson, Elliot Epner
Publikováno v:
Genes & Development. 9:2203-2213
The beta-globin locus control region (LCR) is a complex regulatory element that is essential for the appropriate red cell-specific expression of all cis-linked beta-globin genes. Of the five hypersensitive sites that define the LCR, only 5'HS2 has be