Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Agnes Tantos"'
Autor:
Xuanmao Jiao, Gabriele Di Sante, Mathew C. Casimiro, Agnes Tantos, Anthony W. Ashton, Zhiping Li, Yen Quach, Dharmendra Bhargava, Agnese Di Rocco, Claudia Pupo, Marco Crosariol, Tamas Lazar, Peter Tompa, Chenguang Wang, Zuoren Yu, Zhao Zhang, Kawthar Aldaaysi, Ratna Vadlamudi, Monica Mann, Emmanuel Skordalakes, Andrew Kossenkov, Yanming Du, Richard G. Pestell
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-16 (2024)
Abstract The essential G1-cyclin, CCND1, is frequently overexpressed in cancer, contributing to tumorigenesis by driving cell-cycle progression. D-type cyclins are rate-limiting regulators of G1-S progression in mammalian cells via their ability to b
Externí odkaz:
https://doaj.org/article/ed7bbe79a9f845d2902e34120e2479e7
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 445 (2024)
Background: The scaffold protein tyrosine kinase substrate 4 (TKS4) undergoes tyrosine phosphorylation by the epidermal growth factor receptor (EGFR) pathway via Src kinase. The TKS4 deficiency in humans is responsible for the manifestation of a gene
Externí odkaz:
https://doaj.org/article/36b6b05f730647a2b1258987e0271796
Autor:
Harem Muhamad Amin, Beata Szabo, Rawan Abukhairan, Andras Zeke, József Kardos, Eva Schad, Agnes Tantos
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16032 (2023)
For several histone lysine methyltransferases (HKMTs), RNA binding has been already shown to be a functionally relevant feature, but detailed information on the RNA interactome of these proteins is not always known. Of the six human KMT2 proteins res
Externí odkaz:
https://doaj.org/article/a8770e40b44249f9883886585245d351
Autor:
Joris Van Lindt, Anna Bratek-Skicki, Phuong N. Nguyen, Donya Pakravan, Luis F. Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Van Lindt, Bratek-Skicki et al. show that at carefully selected pH values, proteins can be kept in solution and their LLPS can then be induced by a jump to native pH. This presents a generic method to study the full kinetic trajectory of LLPS under n
Externí odkaz:
https://doaj.org/article/b7ebf01cce4d42dd989460bcbd0ea84b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1310 (2023)
Tks4 is a large scaffold protein in the EGFR signal transduction pathway that is involved in several cellular processes, such as cellular motility, reactive oxygen species-dependent processes, and embryonic development. It is also implicated in a rar
Externí odkaz:
https://doaj.org/article/06ce6e025d9545aab2f5875c2ad9d61e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6150 (2022)
The 96-residue-long loop of EZH2 is proposed to play a role in the interaction with long non-coding RNAs (lncRNAs) and to contribute to EZH2 recruitment to the chromatin. However, molecular details of RNA recognition have not been described so far. C
Externí odkaz:
https://doaj.org/article/2bc504f556e1427dbc194ec0a4515b56
Autor:
Nikoletta Murvai, Lajos Kalmar, Beata Szabo, Eva Schad, András Micsonai, József Kardos, László Buday, Kyou-Hoon Han, Peter Tompa, Agnes Tantos
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6190 (2021)
Disordered plant chaperones play key roles in helping plants survive in harsh conditions, and they are indispensable for seeds to remain viable. Aside from well-known and thoroughly characterized globular chaperone proteins, there are a number of int
Externí odkaz:
https://doaj.org/article/a68e27187c88429fb03ddf3c53806c3f
Autor:
Joris Van Lindt, Anna Bratek-Skicki, Phuong N. Nguyen, Donya Pakravan, Luis F. Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01853-4.
Externí odkaz:
https://doaj.org/article/d19b668ccaf348b4b1dce157fe825693
Autor:
Nikoletta Murvai, Lajos Kalmar, Bianka Szalaine Agoston, Beata Szabo, Agnes Tantos, Gyorgy Csikos, András Micsonai, József Kardos, Didier Vertommen, Phuong N. Nguyen, Nevena Hristozova, Andras Lang, Denes Kovacs, Laszlo Buday, Kyou-Hoon Han, Andras Perczel, Peter Tompa
Publikováno v:
Cells, Vol 9, Iss 8, p 1856 (2020)
Details of the functional mechanisms of intrinsically disordered proteins (IDPs) in living cells is an area not frequently investigated. Here, we dissect the molecular mechanism of action of an IDP in cells by detailed structural analyses based on an
Externí odkaz:
https://doaj.org/article/a96d9daf9aa44ebcb560391ddc417c44
Autor:
Beata Szabo, Tamas Horvath, Eva Schad, Nikoletta Murvai, Agnes Tantos, Lajos Kalmar, Lucía Beatriz Chemes, Kyou-Hoon Han, Peter Tompa
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2119 (2019)
(1) Background: Processivity is common among enzymes and mechanochemical motors that synthesize, degrade, modify or move along polymeric substrates, such as DNA, RNA, polysaccharides or proteins. Processive enzymes can make multiple rounds of modific
Externí odkaz:
https://doaj.org/article/3f71db572b724e57984232770e6162a9