Výsledky vyhledávání - "Agnes Strassberger"

Supplementary Methods, Tables 1-2, Figures 1--3 from Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1α in Advanced Solid Tumors

Autor: Giovanni Melillo, James H. Doroshow, Anthony J. Murgo, Peter Choyke, Ismail Baris Turkbey, Xiaohong Chen, William D. Figg, Shawn D. Spencer, Annamaria Rapisarda, Seth M. Steinberg, Deborah Allen, Agnes Strassberger, Yvonne Horneffer, Lamin Juwara, Mark Raffeld, Shivaani Kummar

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ed6d161ad3684caab88a8d6c71a270
https://doi.org/10.1158/1078-0432.22443482

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Data from Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1α in Advanced Solid Tumors

Purpose: Hypoxia-inducible factor 1 (HIF-1) α is frequently overexpressed in human tumors and is associated with angiogenesis and metastasis. Topotecan, a topoisomerase I inhibitor, has been shown to inhibit HIF-1α expression in preclinical models.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009a708f5cad832d1e35d7b8d4352d71
https://doi.org/10.1158/1078-0432.c.6519830.v1

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Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1α in Advanced Solid Tumors

Autor: Lamin Juwara, James H. Doroshow, Deborah Allen, Anthony J. Murgo, Giovanni Melillo, Yvonne Horneffer, Shawn D. Spencer, William D. Figg, Peter L. Choyke, Seth M. Steinberg, Ismail B. Turkbey, Annamaria Rapisarda, Xiaohong Chen, Shivaani Kummar, Mark Raffeld, Agnes Strassberger

Publikováno v: Clinical Cancer Research. 17:5123-5131

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d03c35e3c00e068e9ac7330465fa9d9
https://doi.org/10.1158/1078-0432.ccr-11-0682

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