Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Agnes Schulte"'
Publikováno v:
Archives of Toxicology. 94:955-957
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd12c05450d5086aaa761c7d74f5305
https://doi.org/10.1007/s00204-020-02681-x
https://doi.org/10.1007/s00204-020-02681-x
Autor:
Agnes Schulte, Alexander Roloff, Nils Lüttgert, Daniel Stalter, Morgane Even, Christoph Hutzler, Jonathan Beauchamp, Andreas Luch
Plastic costume masks regularly exhibit unpleasant odors that may be associated with the emissions of volatile organic compounds (VOCs). Upon inhalation, VOCs might adversely affect the wearer’s health if the exposure exceeds regulatory threshold v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dbeee8dd9a5da31f049c4fb43ef11d
Publikováno v:
Archives of Toxicology. 92:1343-1347
In October 2016, the German REACH Congress was held at the German Federal Institute for Risk Assessment (BfR) in Berlin. Here, the associated improvement made in the fields of consumer protection and the progress in and experiences gained from the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792c731067efbd8308e46dc3a41ff8e6
https://doi.org/10.1007/s00204-018-2175-2
https://doi.org/10.1007/s00204-018-2175-2
Autor:
Annette Romeike, H. Harleman, Agnes Schulte, A. Popp, Jeffery A Engelhardt, Thomas Nolte, Barbara Lenz, B. Silva Lima, Takanori Harada, Xavier Palazzi, Sibylle Gröters, Lindsay Tomlinson, Charles E. Wood, J. Willard, S. Kustermann, Midori Yoshida, H. Fischer, Annamaria Braendli-Baiocco, Sabine Francke, Gabriele Pohlmeyer-Esch, R. Fukuda, W. Kaufmann, Pierluigi Fant
Publikováno v:
Toxicologic Pathology. 46:224-246
Lysosomes have a central role in cellular catabolism, trafficking, and processing of foreign particles. Accumulation of endogenous and exogenous materials in lysosomes represents a common finding in nonclinical toxicity studies. Histologically, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a72dd607119a2fb706ca3f84a051997c
https://doi.org/10.1177/0192623317749452
https://doi.org/10.1177/0192623317749452
Autor:
Paul G. Germann, Sabine Francke, Lindsay Tomlinson, Johannes Harleman, Gabriele Pohlmeyer-Esch, Charles E. Wood, Hirofumi Nagai, Agnes Schulte, Barbara Lenz, Henri Caplain, Takanori Harada, Xavier Palazzi, Mikala Skydsgaard, John E. Burkhardt, Wolfgang Kaufmann, Midori Yoshida, Sibylle Gröters, Kosei Inui, Vicki L. Dellarco, Pierluigi Fant, John R. Foster
Publikováno v:
Toxicologic pathology. 44(6)
The identification of adverse health effects has a central role in the development and risk/safety assessment of chemical entities and pharmaceuticals. There is currently a need for better alignment regarding how nonclinical adversity is determined a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c65f43a3105bdece86ef9cda7acd8e
https://pubmed.ncbi.nlm.nih.gov/27102650
https://pubmed.ncbi.nlm.nih.gov/27102650
Autor:
Robert R. Maronpot, Agnes Schulte, Karin Küttler, A. Nishikawa, Takanori Harada, Anthony P. Hall, Thomas Nolte, David E. Malarkey, John R. Foster, C. R. Elcombe, Wolfgang Kaufmann, Volker Strauss, Malcolm York, Anja Knippel
Publikováno v:
Toxicologic Pathology. 40:971-994
Preclinical toxicity studies have demonstrated that exposure of laboratory animals to liver enzyme inducers during preclinical safety assessment results in a signature of toxicological changes characterized by an increase in liver weight, hepatocellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f38d6a24bb4bb1d355c8c32f44a4c5
https://doi.org/10.1177/0192623312448935
https://doi.org/10.1177/0192623312448935
Autor:
Fréderique Istace, Sinead McMickan, Agnes Schulte, Helmut Fleig, Marie-Noëlle Blaude, Peter Howden, Andre Muller, Edel Healy, Helene Jacobsen
Publikováno v:
Regulatory Toxicology and Pharmacology. 45:229-241
Haemolytic anaemia is often induced following prolonged exposure to chemical substances. Currently, under EU Council Directive 67/548/EEC, substances which induce such effects are classified as dangerous and assigned the risk phrase R48 'Danger of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767dbfd14c925343251a1b0c6502213a
https://doi.org/10.1016/j.yrtph.2006.04.004
https://doi.org/10.1016/j.yrtph.2006.04.004
Autor:
Anne Provencher Bolliger, Catherine George, Paul-Georg Germann, Agnes Schulte, Alys Bradley, Christine Ruehl-Fehlert
Publikováno v:
Experimental and Toxicologic Pathology. 57:1-5
As part of the ICH process of harmonization of testing guidelines for immunotoxicity, the European Society of Toxicologic Pathology (ESTP) has contributed to the scientific discussion on methods and evaluation of immunotoxicity studies with technical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d9f608ef859634410437db6e963eaf
https://doi.org/10.1016/j.etp.2005.03.001
https://doi.org/10.1016/j.etp.2005.03.001
Autor:
Klaus Wettig, Ingrid Gerner, Horst Spielmann, Richard Vogel, Agnes Schulte, Thomas Höfer, Ursula Gundert-Remy, Manfred Liebsch
Publikováno v:
Archives of Toxicology. 78:549-564
During the past 20 years the EU legislation for the notification of chemicals has focussed on new chemicals and at the same time failed to cover the evaluation of existing chemicals in Europe. Therefore, in a new EU chemicals policy (REACH, Registrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3711d3aafca400efd3ec789c4177422d
https://doi.org/10.1007/s00204-004-0577-9
https://doi.org/10.1007/s00204-004-0577-9
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 46:405-415
Der Nachweis von Acrylamid in Lebensmitteln gibt zu erheblicher Besorgnis Anlass. Acrylamid ist ein toxischer Stoff, der im Tierversuch u. a.neurotoxisch und Krebs erzeugend wirkt; es gibt keinen Anlass anzunehmen, dass diese Wirkungen nicht auch im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22feb25638cc0b93f513d3722633d9e
https://doi.org/10.1007/s00103-003-0610-9
https://doi.org/10.1007/s00103-003-0610-9