Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Agnes S. Klar"'
CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo
Autor:
Monica Nanni, Dominic Rütsche, Curdin Bächler, Luca Pontiggia, Agnes S. Klar, Ueli Moehrlen, Thomas Biedermann
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-21 (2023)
Abstract Background CD146 is a cell adhesion molecule whose expression profile in human skin has not yet been elucidated. Here, we characterize CD146 expression pattern in human skin, in particular in blood endothelial cells (BECs) and lymphatic endo
Externí odkaz:
https://doaj.org/article/1c5ce1b6362a414fbf33e2da2a46a625
Autor:
Katarzyna Michalak-Micka, Agnes S. Klar, Athanasia Dasargyri, Thomas Biedermann, Ernst Reichmann, Ueli Moehrlen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract CD26, also known as dipeptidyl peptidase IV (DPPIV), is a multifunctional transmembrane protein playing a significant role in the cutaneous wound healing processes in the mouse skin. However, only scarce data are available regarding the dist
Externí odkaz:
https://doaj.org/article/6e9128de19dd4219baf68b4a70a121a3
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14726 (2023)
Human keratinocytes play a crucial role during skin wound healing and in skin replacement therapies. The secretome of adipose-derived stem cells (ASCs) has been shown to secrete pro-healing factors, among which include TGF-β1, which is essential for
Externí odkaz:
https://doaj.org/article/1dd13d833b3e4f688a450d6d224875a0
Autor:
Dominika Zielinska, Hesham K. Yosef, Tilo Zollitsch, Johann Kern, Yvonne Jakob, David Gvaramia, Nicole Rotter, Luca Pontiggia, Ueli Moehrlen, Thomas Biedermann, Agnes S. Klar
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2588 (2023)
Microtia is a congenital condition of abnormal development of the outer ear. Tissue engineering of the ear is an alternative treatment option for microtia patients. However, for this approach, the identification of high regenerative cartilage progeni
Externí odkaz:
https://doaj.org/article/6897733ed6f14453b28e383b284355c1
Autor:
Katarzyna Michalak-Micka, Dominic Rütsche, Luca Mazzone, Vanessa L. Büchler, Ueli Moehrlen, Agnes S. Klar, Thomas Biedermann
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Human skin contains specialized neuroendocrine Merkel cells responsible for fine touch sensation. In the present study, we performed in-depth analysis of Merkel cells in human fetal back skin. We revealed that these Merkel cells expressed cytokeratin
Externí odkaz:
https://doaj.org/article/60bf9fb1a7994e4a9e025c38298941bb
Autor:
Katarzyna Michalak-Micka, Dominic Rütsche, Lukas Johner, Ueli Moehrlen, Thomas Biedermann, Agnes S. Klar
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 676 (2022)
CD157 acts as a receptor, regulating leukocyte trafficking and the binding of extracellular matrix components. However, the expression pattern and the role of CD157 in human blood (BEC) and the lymphatic endothelial cells (LEC) of human dermal microv
Externí odkaz:
https://doaj.org/article/5d9e960bf6894e8dbd0a6abd98e6b297
Autor:
Dominic Rütsche, Katarzyna Michalak-Micka, Dominika Zielinska, Hannah Moll, Ueli Moehrlen, Thomas Biedermann, Agnes S. Klar
Publikováno v:
Cells, Vol 11, Iss 6, p 1055 (2022)
CD200 is a cell membrane glycoprotein that interacts with its structurally related receptor (CD200R) expressed on immune cells. We characterized CD200–CD200R interactions in human adult/juvenile (j/a) and fetal (f) skin and in in vivo prevasculariz
Externí odkaz:
https://doaj.org/article/eaaa6b6173ac476c9514575b5caf61a9
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 118 (2022)
The immune system has a crucial role in skin wound healing and the application of specific cell-laden immunomodulating biomaterials emerged as a possible treatment option to drive skin tissue regeneration. Cell-laden tissue-engineered skin substitute
Externí odkaz:
https://doaj.org/article/5e8b504c951a4bd2a6ea655846fd24b7
Autor:
Shima Tavakoli, Agnes S. Klar
Publikováno v:
Applied Sciences, Vol 11, Iss 4, p 1493 (2021)
As the largest organ in the human body, the skin has the function of maintaining balance and protecting from external factors such as bacteria, chemicals, and temperature. If the wound does not heal in time after skin damage, it may cause infection o
Externí odkaz:
https://doaj.org/article/96337ab9575948059bd7c2a3ab69a1a1
Autor:
Shima Tavakoli, Agnes S. Klar
Publikováno v:
Biomolecules, Vol 10, Iss 8, p 1169 (2020)
Skin is the largest organ of the human body, protecting it against the external environment. Despite high self-regeneration potential, severe skin defects will not heal spontaneously and need to be covered by skin substitutes. Tremendous progress has
Externí odkaz:
https://doaj.org/article/495b0a3813b04497a7d858892ab9cd8f