Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Agnes S M, Yong"'
Autor:
Nadia El Khawanky, Amy Hughes, Wenbo Yu, Renier Myburgh, Tony Matschulla, Sanaz Taromi, Konrad Aumann, Jade Clarson, Janaki Manoja Vinnakota, Khalid Shoumariyeh, Cornelius Miething, Angel F. Lopez, Michael P. Brown, Justus Duyster, Lutz Hein, Markus G. Manz, Timothy P. Hughes, Deborah L. White, Agnes S. M. Yong, Robert Zeiser
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The success of CAR-T cells for treating acute myeloid leukaemia (AML) is hampered by toxicity to normal cells and low CAR-T cell persistence. Here, the authors show that the demethylating compound 5′-Azacitdine increases anti-CD123 CAR-T cell cytot
Externí odkaz:
https://doaj.org/article/fe5a9441efac4b52a10770a66f35954d
Autor:
Yazad D. Irani, Chung H. Kok, Jade Clarson, Naranie Shanmuganathan, Susan Branford, David T. Yeung, David M. Ross, Timothy P. Hughes, Agnes S. M. Yong
Publikováno v:
Blood Advances. 7:2364-2374
Dysregulation of immune-checkpoint receptors has been reported at diagnosis of chronic myeloid leukemia (CML), however, their role in the maintenance of remission after tyrosine kinase inhibitor (TKI) cessation is unclear. We assessed programmed cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863ea30bd050ebfe93a90f31baaa89cd
https://doi.org/10.1182/bloodadvances.2022008854
https://doi.org/10.1182/bloodadvances.2022008854
Autor:
Agnes S. M. Yong, Amy Hughes
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Chronic myeloid leukemia (CML) is a hematological cancer, characterized by a reciprocal chromosomal translocation between chromosomes 9 and 22 [t(9;22)], producing the Bcr-Abl oncogene. Tyrosine kinase inhibitors (TKIs) represent the standard of care
Externí odkaz:
https://doaj.org/article/999547cc4cd44beab0b1ade6c37ca8f2
Autor:
Markus G. Manz, Deborah L. White, Jade Clarson, Konrad Aumann, Angel F. Lopez, Cornelius Miething, Wenbo Yu, Timothy P. Hughes, Lutz Hein, Janaki Manoja Vinnakota, Amy Hughes, Sanaz Taromi, Robert Zeiser, Tony Matschulla, Justus Duyster, Khalid Shoumariyeh, Agnes S. M. Yong, Renier Myburgh, Michael P. Brown, Nadia El Khawanky
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Successful treatment of acute myeloid leukemia (AML) with chimeric antigen receptor (CAR) T cells is hampered by toxicity on normal hematopoietic progenitor cells and low CAR T cell persistence. Here, we develop third-generation anti-CD123 CAR T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade50715e480524133a7a77d2fb6b639
https://doi.org/10.1038/s41467-021-26683-0
https://doi.org/10.1038/s41467-021-26683-0
Autor:
Agnes S. M. Yong, Sophie Watts, Randall H. Grose, Timothy P. Hughes, Phuong Dang, Susan Branford, David T Yeung, Ilaria S. Pagani, Chung H. Kok, Zandy Rwodzi, Haley Altamura, Naranie Shanmuganathan, Jennifer McLean, Verity A Saunders, Lisa Carne, Jodi Braley, David M. Ross, Deborah L. White
Publikováno v:
Leukemia. 34:1052-1061
Approximately half of patients with chronic myeloid leukemia (CML) in sustained deep molecular response who discontinue tyrosine kinase inhibitors (TKIs) remain in treatment-free remission (TFR). Some of these patients have measurable residual diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e823d627139edf17eaa125758e2bc244
https://doi.org/10.1038/s41375-019-0647-x
https://doi.org/10.1038/s41375-019-0647-x
Autor:
Nicole Loft, Agnes S. M. Yong, Amanda D. Hutchinson, Carlene Wilson, Elise Thompson, Ian D. Lewis
Publikováno v:
European journal of cancer careREFERENCES. 30(5)
Objective: The objective of this exploratory study was to determine the presence and correlates of self-reported cognition in a sample of haematological cancer patients who had undergone allogeneic stem cell transplantation (SCT). Methods: Haematolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09ca35833c91449c41955141ab9636f
https://pubmed.ncbi.nlm.nih.gov/33774876
https://pubmed.ncbi.nlm.nih.gov/33774876
Autor:
Amy Hughes, Deborah L. White, Yazad Irani, Agnes S. M. Yong, David M. Ross, Jade Clarson, Chung H. Kok, David T Yeung, Timothy P. Hughes, Naranie Shanmuganathan
There is currently no biomarker that reliably predicts treatment-free remission (TFR) in chronic myeloid leukaemia (CML). We characterised effector and suppressor immune responses at the time of tyrosine kinase inhibitor (TKI) cessation in patients f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f66a738e908b1da5b0a2e010916a68a
https://hdl.handle.net/11541.2/142425
https://hdl.handle.net/11541.2/142425
Autor:
Devendra K Hiwase, Vidya Limaye, Barbara Koszyca, Adam Maundrell, Julia New-Tolley, Ian D. Lewis, Caroline Smith, Sophia Otto, Peter G Bardy, Agnes S. M. Yong
Publikováno v:
Muscle & Nerve. 58:790-795
Introduction,: Graft-versus-host disease (GVHD) is a recognized complication of allogeneic stem cell transplantation (allo-SCT) and may affect muscle. We investigated the incidence and subtypes of inflammatory myopathy (IM) in South Australian recipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::043c639de12c0935aa577288e8945514
https://doi.org/10.1002/mus.26341
https://doi.org/10.1002/mus.26341
Autor:
Ian D. Lewis, Li Yan A Wee, Devendra K Hiwase, Suzanne Edwards, Kirsty Sharplin, Agnes S. M. Yong, Silke Danner, Daniel Thomas, Deepak Singhal, Andrew H. Wei
Publikováno v:
Journal of geriatric oncology. 12(2)
The incidence of acute myeloid leukemia (AML) in older patients is increasing, but practice guidelines balancing quality-of-life, time outside of hospital and overall survival (OS) are not established.We conducted a retrospective analysis comparing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d266a51d38b9011edc741aaebd20fc02
https://pubmed.ncbi.nlm.nih.gov/32713804
https://pubmed.ncbi.nlm.nih.gov/32713804
Autor:
Chun Kei Kris Ma, Agnes S. M. Yong, Chris Fraser, Emily Blyth, Jane Burgess, David Gottlieb, Leighton Clancy, Barbara Withers, Ming-Celine Dubosq, David Bishop, Gaurav Sutrave, Peter J. Shaw, Kenneth P. Micklethwaite, Renee Simms, Rebecca Brown, David Kliman
Publikováno v:
Blood Advances. 1:2193-2205
Donor-derived adoptive T-cell therapy is a safe and effective treatment of viral infection posttransplant, but it is limited by donor serostatus and availability and by its personalized nature. Off-the-shelf, third-party virus-specific T cells (VSTs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694501d3dc12cf6c674942c86333ab24
https://doi.org/10.1182/bloodadvances.2017010223
https://doi.org/10.1182/bloodadvances.2017010223