Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Agnes Malysa"'
Autor:
Adrianne Wallace-Povirk, Lisa Rubinsak, Agnes Malysa, Sijana H. Dzinic, Manasa Ravindra, Mathew Schneider, James Glassbrook, Carrie O’Connor, Zhanjun Hou, Seongho Kim, Jessica Back, Lisa Polin, Robert T. Morris, Aleem Gangjee, Heather Gibson, Larry H. Matherly
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Novel therapies are urgently needed for epithelial ovarian cancer (EOC), the most lethal gynecologic malignancy. In addition, therapies that target unique vulnerabilities in the tumor microenvironment (TME) of EOC have largely been unrealize
Externí odkaz:
https://doaj.org/article/02853bc9f796452ca78238c2e5dbf371
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1862 (2022)
The pandemic of COVID-19 was caused by a novel coronavirus termed as SARS-CoV2 and is still ongoing with high morbidity and mortality rates in the whole world. The pathogenesis of COVID-19 is highly linked with over-active immune and inflammatory res
Externí odkaz:
https://doaj.org/article/9a610074d808483d85f239eb0f709b12
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58091 (2013)
Gemcitabine is among the most efficacious and widely used antimetabolite agents. Its molecular targets are ribonucleotide reductase M1 (RRM1) and elongating DNA. Acquired and de novo resistance as a result of RRM1 overexpression are major obstacles t
Externí odkaz:
https://doaj.org/article/1f6fb0eb1d5d46e69fff77bbf52c2a35
Autor:
Nerissa T. Viola-Villegas, Wei-Zen Wei, Joyce Reyes, Claire E. McCarthy, Wendy N. Wiesend, Greg Dyson, Agnes Malysa, Brooke N. McKnight, Heather M. Gibson
Primer sequences and biodistribution data for the anti-IFN-gamma PET tracer are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01df0829d07e0efee226e61c3dca234
https://doi.org/10.1158/0008-5472.22419963.v1
https://doi.org/10.1158/0008-5472.22419963.v1
Autor:
Nerissa T. Viola-Villegas, Wei-Zen Wei, Joyce Reyes, Claire E. McCarthy, Wendy N. Wiesend, Greg Dyson, Agnes Malysa, Brooke N. McKnight, Heather M. Gibson
Time course imaging of anti-CD3 and anti-IFN-gamma PET tracers, as well as images from all experimental mice are shown. Additional quality control measures such as tracer uptake in the spleen and 100x magnification of IHC samples are included.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c07c9bbf7bf44311a68e94f9dfe8fd1
https://doi.org/10.1158/0008-5472.22419969.v1
https://doi.org/10.1158/0008-5472.22419969.v1
Autor:
Nerissa T. Viola-Villegas, Wei-Zen Wei, Joyce Reyes, Claire E. McCarthy, Wendy N. Wiesend, Greg Dyson, Agnes Malysa, Brooke N. McKnight, Heather M. Gibson
IFNγ is an attractive target for imaging active antitumor immunity due to its function in the T-cell signaling axis. Here, we test an IFNγ immuno-PET (immunoPET) probe for its capacity to identify adaptive immunotherapy response after HER2/neu vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59182341835446936f790c9afd829ebb
https://doi.org/10.1158/0008-5472.c.6510519.v1
https://doi.org/10.1158/0008-5472.c.6510519.v1
Autor:
Agnes Malysa, Wenlong Bai, Hyejeong Jang, Steve M. Patrick, Joseph A. Caruso, Chen Hu, Joshua Heyza, Cong li Hu, Paul M. Stemmer, Niko Moses, Xiaohong Mary Zhang, Gerold Bepler, Wei Chen, Zhenkun Lou, Lisa Polin, Shengyan Xiang, Mu Zhang, Chuangui Wang
Publikováno v:
Cell Death and Disease, Vol 11, Iss 5, Pp 1-18 (2020)
Cell Death & Disease
Cell Death & Disease
Ubiquitin-specific peptidase 10 (USP10) stabilizes both tumor suppressors and oncogenes in a context-dependent manner. However, the nature of USP10’s role in non-small cell lung cancer (NSCLC) remains unclear. By analyzing The Cancer Genome Atlas (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8387a37b13c5864bed4364357aa1505e
http://link.springer.com/article/10.1038/s41419-020-2519-8
http://link.springer.com/article/10.1038/s41419-020-2519-8
Autor:
Adrianne Wallace-Povirk, Lisa Rubinsak, Agnes Malysa, Sijana H. Dzinic, Manasa Ravindra, Mathew Schneider, James Glassbrook, Carrie O’Connor, Zhanjun Hou, Seongho Kim, Jessica Back, Lisa Polin, Robert T. Morris, Aleem Gangjee, Heather Gibson, Larry H. Matherly
Publikováno v:
Scientific reports. 12(1)
Novel therapies are urgently needed for epithelial ovarian cancer (EOC), the most lethal gynecologic malignancy. In addition, therapies that target unique vulnerabilities in the tumor microenvironment (TME) of EOC have largely been unrealized. One st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de112fdd7233075799791c0155f68695
https://pubmed.ncbi.nlm.nih.gov/35790779
https://pubmed.ncbi.nlm.nih.gov/35790779
Autor:
Thomas McFall, Mike R. Wilson, Agnes Malysa, Rayna Rosati, Larry H. Matherly, Manohar Ratnam, Jessica B. Back, Mugdha Patki, Yanfang Huang, Abigail Fielder, Lisa Polin, Gerold Bepler, Fulvio Lonardo, Jing Li
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Dexamethasone (Dex), co-administered to lung adenocarcinoma patients with pemetrexed chemotherapy, protects against pemetrexed cytotoxicity by inducing reversible G1 arrest, reflected by the effect of Dex on FLT-PET images of patient tumors. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d328fc1b1eb01b520ae7a3bdc074a9
http://link.springer.com/article/10.1038/s41598-018-34475-8
http://link.springer.com/article/10.1038/s41598-018-34475-8
Autor:
Agnes Malysa, Gerold Bepler, Rodrigo Fernandez-Valdivia, Carlos Redondo, Wei Chen, Hyejeong Jang, May Chammaa
Publikováno v:
Journal of Cellular Physiology. 233:9548-9562
Recent comprehensive next-generation genome and transcriptome analyses in lung cancer patients, several clinical observations, and compelling evidence from mouse models of lung cancer have uncovered a critical role for Notch signaling in the initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a179ed22af7113d98c8c4637c6c3f72c
https://doi.org/10.1002/jcp.26858
https://doi.org/10.1002/jcp.26858