Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Agnes M. Azimzadeh"'
Autor:
Natalie A. O’Neill, MD, Tianshu Zhang, MD, PhD, Gheorghe Braileanu, PhD, Xiangfei Cheng, MD, PhD, Alena Hershfeld, MS, Wenji Sun, MD, PhD, Keith A. Reimann, PhD, Sia Dahi, MD, Natalia Kubicki, MD, Wessam Hassanein, MD, Christopher Laird, MD, Arielle Cimeno, MD, Agnes M. Azimzadeh, PhD, Richard N. Pierson, MD
Publikováno v:
Transplantation Direct, Vol 4, Iss 2, p e344 (2018)
Background. Inducible costimulator (ICOS) is rapidly upregulated with T-cell stimulation and may represent an escape pathway for T-cell costimulation in the setting of CD40/CD154 costimulation blockade. Induction treatment exhibited no efficacy in a
Externí odkaz:
https://doaj.org/article/a36769921a3249b3820e3589d28a5ee9
Autor:
Selin Sendil, MD, Silviu C. Diaconu, MD, Natalie A. O’Neill, MD, Lars Burdorf, MD, Ivan Tatarov, DVM, Dawn M. Parsell, BS, Agnes M. Azimzadeh, PhD, Richard N. Pierson, III, MD, Arthur J. Nam, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 5, Iss 12, p e1538 (2017)
Background:. Vascularized composite allotransplantation is constrained by complications associated with standard immunosuppressive strategies. Vascularized thymus and bone marrow have been shown to promote prolonged graft survival in composite organ
Externí odkaz:
https://doaj.org/article/ccd32a5673d541079347e97efa3e3b55
Autor:
Ryan Chaban, Zahra Habibabady, Wessam Hassanein, Margaret R. Connolly, Lars Burdorf, Emily Redding, Christopher Laird, Jolene Ranek, Gheorghe Braileanu, Selin Sendil, Xiangfei Cheng, Wenji Sun, Natalie A. O'Neill, Kasinath Kuravi, Sunghoon Hurh, David L. Ayares, Agnes M. Azimzadeh, Richard N. Pierson
Publikováno v:
Xenotransplantation. 29
Antibody-mediated rejection has long been known to be one of the major organ failure mechanisms in xenotransplantation. In addition to the porcine α1,3-galactose (α1,3Gal) epitope, N-Glycolylneuraminic acid (Neu5Gc), a sialic acid, has been identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b3de465a5834f3dc56b1ff90de64ea
https://doi.org/10.1111/xen.12784
https://doi.org/10.1111/xen.12784
Autor:
Kaitlyn Petitpas, Zahra Habibabady, Veronica Ritchie, Margaret R. Connolly, Lars Burdorf, Wenning Qin, Yinan Kan, Jacob V. Layer, Juliet N. Crabtree, Michele E. Youd, William F. Westlin, Diogo M. Magnani, Richard N. Pierson, Agnes M. Azimzadeh
Publikováno v:
XenotransplantationREFERENCES.
The phenomenon of diminishing hematocrit after in vivo liver and lung xenotransplantation and during ex vivo liver xenoperfusion has largely been attributed to action by resident liver porcine macrophages, which bind and destroy human erythrocytes. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5994e175ef5f35d2a527596cef73974
https://pubmed.ncbi.nlm.nih.gov/36125388
https://pubmed.ncbi.nlm.nih.gov/36125388
Autor:
Arielle Cimeno, Kasinath Kuravi, Lori Sorrells, Amy Dandro, Selin Sendil, Lars Burdorf, Dawn M. Parsell, Will Eyestone, Carol Phelps, David Ayares, Agnes M. Azimzadeh, Richard N. Pierson, Rolf N. Barth, John C. LaMattina
Publikováno v:
Xenotransplantation
INTRODUCTION: Platelet sequestration, inflammation, and inappropriate coagulation cascade activation are prominent in liver xenotransplant models and are associated with poor outcomes. Here, we evaluate a cassette of six additional genetic modificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50be7e88fc8c555827c271fbc6627e18
https://doi.org/10.1111/xen.12731
https://doi.org/10.1111/xen.12731
Autor:
Zahra A. Habibabady, Selin Sendil, Felix Ellett, Franziska Pollok, Gabriela F. Elias, Beth M. French, Wenji Sun, Gheorghe Braileanu, Lars Burdorf, Daniel Irimia, Richard N. Pierson, Agnes M. Azimzadeh
Publikováno v:
Xenotransplantation
Platelet sequestration is a common process during organ reperfusion after transplantation. However, instead of lower platelet counts, when using traditional hemocytometers and light microscopy, we observed physiologically implausible platelet counts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bb628297dca2b524639200fef2eb0a
https://doi.org/10.1111/xen.12729
https://doi.org/10.1111/xen.12729
Autor:
Donald G Harris, Prabhjot K Benipal, Xiangfei Cheng, Lars Burdorf, Agnes M Azimzadeh, Richard N Pierson
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123015 (2015)
Porcine xenografts are a promising source of scarce transplantable organs, but stimulate intense thrombosis of human blood despite targeted genetic and pharmacologic interventions. Current experimental models do not enable study of the blood/endothel
Externí odkaz:
https://doaj.org/article/287598f62c904fa08fe495cd4610801c
Autor:
Anthony Kronfli, E. Welty, Xiangfei Cheng, Richard N. Pierson, E. Rybak, Natalie A. O'Neill, Evelyn Sievert, Thomas S. Monahan, Emily Bergbower, Siamak Dahi, Agnes M. Azimzadeh, Gheorghe Braileanu, Chris Avon, Wenji Sun, Tianshu Zhang, Lars Burdorf, Donald G. Harris
Publikováno v:
Transplantation. 102:e90-e100
Selective CD28 inhibition is actively pursued as an alternative to B7 blockade using cytotoxic T lymphocyte antigen 4 Ig based on the hypothesis that the checkpoint immune regulators cytotoxic T lymphocyte antigen 4 and programmed death ligand 1 will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f00b7ee4418a90d73437722c7ab21e
https://doi.org/10.1097/tp.0000000000002044
https://doi.org/10.1097/tp.0000000000002044
Autor:
Peter J. Cowan, Muhammad Mohiuddin, Takaaki Kobayashi, David H. Sachs, Leo Buhler, Curie Ahn, Agnes M. Azimzadeh, Jay A. Fishman, Richard N. Pierson, Wayne J. Hawthorne, Bernhard J. Hering, David K. C. Cooper, Joachim Denner
Publikováno v:
Transplantation, Vol. 101, No 8 (2017) pp. 1766-1769
The continual critical shortage of organs and cells from deceased human donors has stimulated research in the field of cross-species transplantation (xenotransplantation), with the pig selected as the most suitable potential source of organs. Since t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f846808b7a30dddaf1ac7e1e162caeda
https://doi.org/10.1097/tp.0000000000001683
https://doi.org/10.1097/tp.0000000000001683
Preemptive CD20+ B cell Depletion Attenuates Cardiac Allograft Vasculopathy in CD154-Treated Monkeys
Autor:
Richard N. Pierson, Xiangfei Cheng, Anthony Kronfli, C. Avon, Mitch Higuchi, Agnes M. Azimzadeh, Stuart L. Mitchell, Shahrooz S. Kelishadi, Alena Hershfeld, Natalie OʼNeill, E. Rybak, Guosheng Wu, T. Stoddard, E. Welty, Tianshu Zhang, Bao-Ngoc H. Nguyen, Lars Burdorf
Publikováno v:
Transplantation. 101:63-73
Anti-CD154 monotherapy is associated with antidonor allo-antibody (Ab) elaboration, cardiac allograft vasculopathy (CAV), and allograft failure in preclinical primate cell and organ transplant models. In the context of calcineurin inhibitors (CNI), t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6506c6ca58db77d66ab9dafd14e2ed6
https://doi.org/10.1097/tp.0000000000001258
https://doi.org/10.1097/tp.0000000000001258