Zobrazeno 1 - 10 of 124 pro vyhledávání: '"Agnes Lo"'
1
Akademický článek
Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1
Autor: Sarah M. Davis, Vignesh N. Hariharan, Agnes Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa, Nicholas McHugh, Annabelle Biscans, Julia F. Alterman, S. Ananth Karumanchi, Melissa J. Moore, Anastasia Khvorova
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 135-149 (2022)
Preeclampsia (PE) is a rising, potentially lethal complication of pregnancy. PE is driven primarily by the overexpression of placental soluble fms-like tyrosine kinase 1 (sFLT1), a validated diagnostic and prognostic marker of the disease when normal
Externí odkaz: https://doaj.org/article/9a70cf9e7c9f406b9efc376a07ec4325
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2
Akademický článek
Nitroxide—HMP—Protects Human Trophoblast HTR-8/SVneo Cells from H2O2-Induced Oxidative Stress by Reducing the HIF1A Signaling Pathway
Autor: Diana Pintye, Réka Eszter Sziva, Maxim Mastyugin, Marianna Török, Sonako Jacas, Agnes Lo, Saira Salahuddin, Zsuzsanna K. Zsengellér
Publikováno v: Antioxidants, Vol 12, Iss 8, p 1578 (2023)
Preeclampsia (PE) is a pregnancy-specific syndrome affecting 5–7% of patients. There is no effective treatment available. Early abnormal placental development is associated with oxidative stress (OS) and a release of reactive oxygen species (ROS) i
Externí odkaz: https://doaj.org/article/303949927fb940268b508d7af93108bd
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3
Akademický článek
Soluble fms-Like Tyrosine Kinase 1 Localization in Renal Biopsies of CKD
Autor: Zsuzsanna K. Zsengellér, Agnes Lo, Mahtab Tavasoli, Elizabeth Pernicone, S. Ananth Karumanchi, Seymour Rosen
Publikováno v: Kidney International Reports, Vol 4, Iss 12, Pp 1735-1741 (2019)
Introduction: Soluble fms-like tyrosine kinase 1 (sFLT1) is a splice variant of the vascular endothelial growth factor (VEGF) receptor lacking the transmembrane and cytoplasmic domains and acts as a powerful antagonist of VEGF signaling. Plasma sFLT1
Externí odkaz: https://doaj.org/article/ee9bd67e9f1a45cbb54f2311ca1179a6
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5
Akademický článek
Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology.
Autor: Chen Xu, Agnes Lo, Anuradha Yammanuru, Aimee St Clair Tallarico, Kristen Brady, Akikazu Murakami, Natasha Barteneva, Quan Zhu, Wayne A Marasco
Publikováno v: PLoS ONE, Vol 5, Iss 3, p e9625 (2010)
Carbonic anhydrase IX (CAIX, gene G250/MN-encoded transmembrane protein) is highly expressed in various human epithelial tumors such as renal clear cell carcinoma (RCC), but absent from the corresponding normal tissues. Besides the CA signal transduc
Externí odkaz: https://doaj.org/article/c8d96a7cf7ec42d0a6c6947ac85bdb81
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