Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Agnes Fouet"'
Publikováno v:
Microbiol Mol Biol Rev
Phospholipids are vital membrane constituents that determine cell functions and interactions with the environment. For bacterial pathogens, rapid adjustment of phospholipid composition to changing conditions during infection can be crucial for growth
Autor:
Paprapach Wongdontree, Aaron Millan-Oropeza, Jennifer Upfold, Jean-Pierre Lavergne, David Halpern, Clara Lambert, Adeline Page, Gérald Kénanian, Christophe Grangeasse, Céline Henry, Agnès Fouet, Karine Gloux, Jamila Anba-Mondoloni, Alexandra Gruss
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109505- (2024)
Summary: Antibiotics inhibiting the fatty acid synthesis pathway (FASII) of the major pathogen Staphylococcus aureus reach their enzyme targets, but bacteria continue growth by using environmental fatty acids (eFAs) to produce phospholipids. We asses
Externí odkaz:
https://doaj.org/article/f6bf5f3ca6be4f448560f85bfcc04fd3
Autor:
Clara Lambert, Thifaine Poullion, Qiufen Zhang, Alain Schmitt, Jean-Marc Masse, Karine Gloux, Claire Poyart, Agnès Fouet
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284402 (2023)
Membranes contain lipids that are composed of fatty acids (FA) and a polar head. Membrane homeostasis is crucial for optimal bacterial growth and interaction with the environment. Bacteria synthesize their FAs via the FASII pathway. Gram-positive bac
Externí odkaz:
https://doaj.org/article/007ea901d69b440fa05abd4a93457e93
Autor:
Stavroula, Balomenou, Agnes, Fouet, Mary, Tzanodaskalaki, Evelyne, Couture-Tosi, Vassilis, Bouriotis, Ivo G, Boneca
Publikováno v:
Molecular microbiology. 87(4)
Peptidoglycan deacetylases (PGNG-dacs) belong to the Carbohydrate Esterase Family 4 (CE4) and have been described as required for bacterial evasion to lysozyme and innate immune responses. Interestingly, there is an unusual occurrence of 10 putative
Autor:
Agnes Fouet
Publikováno v:
Microbiology. 161:1296-1296
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background The human pathogen Streptococcus pyogenes, or group A Streptococcus, is responsible for mild infections to life-threatening diseases. To facilitate the characterization of regulatory networks involved in the adaptation of this pat
Externí odkaz:
https://doaj.org/article/76d6204615924ab2947a22329a9388d7
Autor:
Gérald Kénanian, Claire Morvan, Antonin Weckel, Amit Pathania, Jamila Anba-Mondoloni, David Halpern, Marine Gaillard, Audrey Solgadi, Laetitia Dupont, Céline Henry, Claire Poyart, Agnès Fouet, Gilles Lamberet, Karine Gloux, Alexandra Gruss
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 3974-3982.e4 (2019)
Summary: The essentiality of fatty acid synthesis (FASII) products in the human pathogen Staphylococcus aureus is the underlying rationale for FASII-targeted antimicrobial drug design. Reports of anti-FASII efficacy in animals support this choice. Ho
Externí odkaz:
https://doaj.org/article/b5cad4a0e4ec4316bfa82390590c6c71
Autor:
Constantin Hays, Gérald Touak, Abdelouhab Bouaboud, Agnès Fouet, Julie Guignot, Claire Poyart, Asmaa Tazi
Publikováno v:
eLife, Vol 8 (2019)
Group B Streptococcus (GBS) is the leading cause of invasive bacterial neonatal infections. Late-onset diseases (LOD) occur between 7 and 89 days of life and are largely due to the CC17 GBS hypervirulent clone. We studied the impact of estradiol (E2)
Externí odkaz:
https://doaj.org/article/48f913a41b0e4becbca0b66a03348708
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101464 (2014)
Group A Streptococcus (GAS) infections remain a significant health care problem due to high morbidity and mortality associated with GAS diseases, along with their increasing worldwide prevalence. Macrophages play a key role in the control and clearan
Externí odkaz:
https://doaj.org/article/9c5cae4d8391428c8bc358d079e76120
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27411 (2011)
LPXTG proteins, present in most if not all Gram-positive bacteria, are known to be anchored by sortases to the bacterial peptidoglycan. More than one sortase gene is often encoded in a bacterial species, and each sortase is supposed to specifically a
Externí odkaz:
https://doaj.org/article/0da9a9ea0c874fd09940231508e0096e