Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Agnes Ernst"'
Autor:
Hendrik Wesseling, Michael G. Gottschalk, Jason D. Cooper, Sabine Bahn, Agnes Ernst, David Alan Cox
Pharmacological and genetic rodent models of schizophrenia play an important role in the drug discovery pipeline, but quantifying the molecular similarity of such models with the underlying human pathophysiology has proved difficult. We developed a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d359cf880fbe83d41af30be7b580fac5
https://www.repository.cam.ac.uk/handle/1810/256667
https://www.repository.cam.ac.uk/handle/1810/256667
Autor:
Hassan Rahmoune, Sabine Bahn, Paul C. Guest, Laura W. Harris, Daniel Martins-de-Souza, Nancy Aerts, Ilse Lenaerts, Murtada Alsaif, Bob Amess, Agnes Ernst, Pieter J. Peeters
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 146 (2012)
BMC Research Notes
BMC Research Notes
Background: Establishing preclinical models is essential for novel drug discovery in schizophrenia. Most existing models are characterized by abnormalities in behavioral readouts, which are informative, but do not necessarily translate to the symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6dc7ec3cdc29714927d7bddeb8caa7f
https://ora.ox.ac.uk/objects/uuid:d8a5e0f4-4f4b-439e-8c73-c0cc894185e8
https://ora.ox.ac.uk/objects/uuid:d8a5e0f4-4f4b-439e-8c73-c0cc894185e8
Autor:
Meyer, Agnes Ernst
Publikováno v:
1915 May 01(3), 2-2.
Externí odkaz:
https://www.jstor.org/stable/25311780
Autor:
Emanuel Schwarz, Sabine Bahn, Agnes Ernst, Zoltán Sarnyai, Wolfgang Kluge, Dan Ma, Paul C. Guest, Isabel Garcia-Perez, Tsz M. Tsang, Elaine Holmes
Publikováno v:
Journal of Proteome Research, 11(7), 3704-3714. American Chemical Society
Administration of the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist phencyclidine (PCP) to rodents is widely used as preclinical model for schizophrenia. Most studies on this model employ methods investigating behavior and brain abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5d39c179d6cb555edeaf9f5963ecbb
https://doi.org/10.1021/pr300197d
https://doi.org/10.1021/pr300197d
Autor:
Jason D. Cooper, David Alan Cox, Michael G. Gottschalk, Agnes Ernst, Hendrik Wesseling, Sabine Bahn
Publikováno v:
European Psychiatry. 41:s807-s807
Rodent models of schizophrenia (SCZ) are indispensable when screening for novel treatments, but quantifying their translational relevance with the underlying human pathophysiology has proved difficult. A novel systems methodology (shown in Figure 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3853175875be6774b0a4024f54555d1d
https://doi.org/10.1016/j.eurpsy.2017.01.1563
https://doi.org/10.1016/j.eurpsy.2017.01.1563
Autor:
Zoltán, Sarnyai, Murtada, Alsaif, Sabine, Bahn, Agnes, Ernst, Paul C, Guest, Eva, Hradetzky, Wolfgang, Kluge, Viktoria, Stelzhammer, Hendrik, Wesseling
Publikováno v:
International review of neurobiology. 101
Modeling neuropsychiatric disorders in animals poses a significant challenge due to the subjective nature of diverse often overlapping symptoms, lack of objective biomarkers and diagnostics, and the rudimentary understanding of the pathophysiology. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05756e3da9f8700f8f308067dfed22d7
https://pubmed.ncbi.nlm.nih.gov/22050853
https://pubmed.ncbi.nlm.nih.gov/22050853
Autor:
Wolfgang Kluge, Hendrik Wesseling, Eva Hradetzky, Paul C. Guest, Viktoria Stelzhammer, Sabine Bahn, Murtada Alsaif, Agnes Ernst, Zoltán Sarnyai
Modeling neuropsychiatric disorders in animals poses a significant challenge due to the subjective nature of diverse often overlapping symptoms, lack of objective biomarkers and diagnostics, and the rudimentary understanding of the pathophysiology. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e492077cb22b38f1919673caea65cef5
https://doi.org/10.1016/b978-0-12-387718-5.00008-0
https://doi.org/10.1016/b978-0-12-387718-5.00008-0
Autor:
G McAllister, Yishai Levin, Dagmar Koethe, Paul C. Guest, Laura W. Harris, K Burling, F M Leweke, Sabine Bahn, Johann Steiner, Marlis Herberth, Matthew T. Wayland, Yagnesh Umrania, Lan Wang, Matthias Rothermundt, Agnes Ernst, J.M. Van Beveren
Publikováno v:
Molecular Psychiatry, 15(2), 118-119. Nature Publishing Group
Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naive schizophrenia patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c902e718a6f6989ee653e71c2ca16368
https://doi.org/10.1038/mp.2009.81
https://doi.org/10.1038/mp.2009.81
Autor:
Khalid M. Elased, Hassan Rahmoune, Agnes Ernst, Sabine Bahn, Ajaykumar N. Sharma, Paul C. Guest
Publikováno v:
Translational Psychiatry, 3. Nature Publishing Group
Translational Psychiatry
Translational Psychiatry
The db/db mouse is a widely used preclinical model in diabetes research. Recent studies have shown that these mice also display aspects of psychosis and depression-like behaviors as seen in some psychiatric disorders. Here, we have performed multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd91b04609ededc89ac4af83bd62fcf
https://doi.org/10.1038/tp.2013.42
https://doi.org/10.1038/tp.2013.42