Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Agnes Ellinghaus"'
Autor:
Julia Mehl, Saeed Khomeijani Farahani, Erik Brauer, Alexandra Klaus‐Bergmann, Tobias Thiele, Agnes Ellinghaus, Eireen Bartels‐Klein, Katharina Koch, Katharina Schmidt‐Bleek, Ansgar Petersen, Holger Gerhardt, Viola Vogel, Georg N. Duda
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Bone fracture healing is regulated by mechanobiological cues. Both, extracellular matrix (ECM) deposition and microvascular assembly determine the dynamics of the regenerative processes. Mechanical instability as by inter‐fragmentary shear
Externí odkaz:
https://doaj.org/article/2bcadc7c650844098b756206036103db
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Metabolites are demonstrated to be critical regulators of fracture healing. Succinate is found to promote vascularization and ossification, highlighting that metabolites have the potential to be used therapeutically to promote fracture healing.
Externí odkaz:
https://doaj.org/article/a53074f46f7c46838b8dcb05d9bcba57
Autor:
Julia Löffler, F. Andrea Sass, Sebastian Filter, Alexander Rose, Agnes Ellinghaus, Georg N. Duda, Anke Dienelt
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Fracture repair is initiated by a multitude of immune cells and induction of an inflammatory cascade. Alterations in the early healing response due to an aged adaptive immune system leads to impaired bone repair, delayed healing or even formation of
Externí odkaz:
https://doaj.org/article/7ee0cefede5b4fd58888b86ea611873d
Autor:
Christian H. Bucher, Claudia Schlundt, Dag Wulsten, F. Andrea Sass, Sebastian Wendler, Agnes Ellinghaus, Tobias Thiele, Ricarda Seemann, Bettina M. Willie, Hans-Dieter Volk, Georg N. Duda, Katharina Schmidt-Bleek
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Bone formation as well as bone healing capacity is known to be impaired in the elderly. Although bone formation is outpaced by bone resorption in aged individuals, we hereby present a novel path that considerably impacts bone formation and architectu
Externí odkaz:
https://doaj.org/article/94d3e1b6fd3a46ae9a560ced95cf5feb
Autor:
Julia C. Berkmann, Aaron X. Herrera Martin, Carlotta Pontremoli, Kai Zheng, Christian H. Bucher, Agnes Ellinghaus, Aldo R. Boccaccini, Sonia Fiorilli, Chiara Vitale Brovarone, Georg N. Duda, Katharina Schmidt-Bleek
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 823 (2020)
Bone morphogenetic protein-2 (BMP-2) is a known key mediator of physiological bone regeneration and is clinically approved for selected musculoskeletal interventions. Yet, broad usage of this growth factor is impeded due to side effects that are majo
Externí odkaz:
https://doaj.org/article/492f0fbfcd9a43fc911fe4d779d4e59a
Autor:
Julia C. Berkmann, Aaron X. Herrera Martin, Agnes Ellinghaus, Claudia Schlundt, Hanna Schell, Evi Lippens, Georg N. Duda, Serafeim Tsitsilonis, Katharina Schmidt-Bleek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2513 (2020)
Local pH is stated to acidify after bone fracture. However, the time course and degree of acidification remain unknown. Whether the acidification pattern within a fracture hematoma is applicable to adjacent muscle hematoma or is exclusive to this reg
Externí odkaz:
https://doaj.org/article/37f709b0e47b475db6def77c9d009010
Autor:
Bernd Preininger, Georg Duda, Hinnerk Gerigk, Jonas Bruckner, Agnes Ellinghaus, F Andrea Sass, Carsten Perka, Katharina Schmidt-Bleek, Anke Dienelt
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e52650 (2013)
Sufficient angiogenesis is crucial during tissue regeneration and therefore also pivotal in bone defect healing. Recently, peripheral blood derived progenitor cells have been identified to have in addition to their angiogenic potential also osteogeni
Externí odkaz:
https://doaj.org/article/4e7cf79915de492d84e4943122a64a70
Autor:
Sarah A. E. Young, Anna-Dorothea Heller, Daniela S. Garske, Maximilian Rummler, Victoria Qian, Agnes Ellinghaus, Georg N. Duda, Bettina M. Willie, Anika Grüneboom, Amaia Cipitria
Breast cancer often metastasizes to bone causing osteolytic lesions. Structural and biophysical changes are rarely studied, yet are hypothesized to influence metastatic progression. Here, we developed a mouse model of early bone metastasis and multim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2d327c34ae49bed8cc7ccbc292940f
https://doi.org/10.1101/2023.01.24.525352
https://doi.org/10.1101/2023.01.24.525352
Autor:
Agnes Ellinghaus, David J. Mooney, Georg N. Duda, Aline Lueckgen, Amaia Cipitria, Daniela S. Garske
Publikováno v:
Acta Biomaterialia. 115:185-196
Hydrogels with patterned biophysical and biochemical properties have found increasing attention in the biomaterials community. In this work, we explore alginate-based materials with two orthogonal crosslinking mechanisms: the spontaneous Diels-Alder
Autor:
Sarah A.E. Young, Maximilian Rummler, Hubert M. Taïeb, Daniela S. Garske, Agnes Ellinghaus, Georg N. Duda, Bettina M. Willie, Amaia Cipitria
Publikováno v:
Bone
The bone structure is very dynamic and continuously adapts its geometry to external stimuli by modeling and remodeling the mineralized tissue. In vivo microCT-based time-lapse morphometry is a powerful tool to study the temporal and spatial dynamics