Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Agnes Delahodde"'
Autor:
Nicola Facchinello, Claudio Laquatra, Lisa Locatello, Giorgia Beffagna, Raquel Brañas Casas, Chiara Fornetto, Alberto Dinarello, Laura Martorano, Andrea Vettori, Giovanni Risato, Rudy Celeghin, Giacomo Meneghetti, Massimo Mattia Santoro, Agnes Delahodde, Francesco Vanzi, Andrea Rasola, Luisa Dalla Valle, Maria Berica Rasotto, Tiziana Lodi, Enrico Baruffini, Francesco Argenton, Natascia Tiso
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract The DNA polymerase gamma (Polg) is a nuclear-encoded enzyme involved in DNA replication in animal mitochondria. In humans, mutations in the POLG gene underlie a set of mitochondrial diseases characterized by mitochondrial DNA (mtDNA) depleti
Externí odkaz:
https://doaj.org/article/e5b4a8a5e87b4483a23748afb74ea087
Autor:
Fernando Gonzalez, Thomas Kodadek, Stephen Albert Johnston, Agnes Delahodde, Thomas G. Gillette
Publikováno v:
Proceedings of the National Academy of Sciences. 101:5904-5909
Recent studies from a number of laboratories have revealed a surprising number of connections between RNA polymerase II transcription and the ubiquitin/proteasome pathway. We now find yet another intersection of these pathways by showing that the 26S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f8d087ca17144c874fb15efd590943
https://doi.org/10.1073/pnas.0305411101
https://doi.org/10.1073/pnas.0305411101
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (18), pp.12614--23
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (18), pp.12614--23
The Saccharomyces cerevisiae Gal4 protein is a paradigmatic transcriptional activator containing a C-terminal acidic activation domain (AD) of 34 amino acids. A mutation that results in the truncation of about two-thirds of the Gal4AD (gal4D) results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1808ca1ce2355c4223b17453dbcabc20
https://hal.archives-ouvertes.fr/hal-00352722
https://hal.archives-ouvertes.fr/hal-00352722
Autor:
Kyle Thompson, Lucas Bianchi, Francesca Rastelli, Florence Piron-Prunier, Sophie Ayciriex, Claude Besmond, Laurence Hubert, Magalie Barth, Inês A. Barbosa, Charu Deshpande, Manali Chitre, Sarju G. Mehta, Eric J.M. Wever, Pascale Marcorelles, Sandra Donkervoort, Dimah Saade, Carsten G. Bönnemann, Katherine R. Chao, Chunyu Cai, Susan T. Iannaccone, Andrew F. Dean, Robert McFarland, Frédéric M. Vaz, Agnès Delahodde, Robert W. Taylor, Agnès Rötig
Publikováno v:
HGG Advances, Vol 3, Iss 2, Pp 100097- (2022)
Summary: Mitochondrial disorders are clinically and genetically heterogeneous, with variants in mitochondrial or nuclear genes leading to varied clinical phenotypes. TAMM41 encodes a mitochondrial protein with cytidine diphosphate-diacylglycerol synt
Externí odkaz:
https://doaj.org/article/3e06951a912a4d6080e971a99e6d10b0
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214287 (2019)
Eukaryotic organelles share different components and establish physical contacts to communicate throughout the cell. One of the best-recognized examples of such interplay is the metabolic cooperation and crosstalk between mitochondria and peroxisomes
Externí odkaz:
https://doaj.org/article/6dfe1d4f64b3420f905e9b5d7dc86501
Autor:
Giulia di Punzio, Maria Antonietta Di Noia, Agnès Delahodde, Carole Sellem, Claudia Donnini, Luigi Palmieri, Tiziana Lodi, Cristina Dallabona
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4461 (2021)
Mitochondrial diseases result from inherited or spontaneous mutations in mitochondrial or nuclear DNA, leading to an impairment of the oxidative phosphorylation responsible for the synthesis of ATP. To date, there are no effective pharmacological the
Externí odkaz:
https://doaj.org/article/f5a8e69591824453a9c3cf302a600029
Autor:
Jean-Paul Lasserre, Alain Dautant, Raeka S. Aiyar, Roza Kucharczyk, Annie Glatigny, Déborah Tribouillard-Tanvier, Joanna Rytka, Marc Blondel, Natalia Skoczen, Pascal Reynier, Laras Pitayu, Agnès Rötig, Agnès Delahodde, Lars M. Steinmetz, Geneviève Dujardin, Vincent Procaccio, Jean-Paul di Rago
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 6, Pp 509-526 (2015)
Mitochondrial diseases are severe and largely untreatable. Owing to the many essential processes carried out by mitochondria and the complex cellular systems that support these processes, these diseases are diverse, pleiotropic, and challenging to st
Externí odkaz:
https://doaj.org/article/d739a034d8d041fb94f29fdbddc8e0fd
Autor:
Cybel Mehawej, Agnès Delahodde, Laurence Legeai-Mallet, Valérie Delague, Nabil Kaci, Jean-Pierre Desvignes, Zoha Kibar, José-Mario Capo-Chichi, Eliane Chouery, Arnold Munnich, Valérie Cormier-Daire, André Mégarbané
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004311 (2014)
Impairment of the tightly regulated ossification process leads to a wide range of skeletal dysplasias and deciphering their molecular bases has contributed to the understanding of this complex process. Here, we report a homozygous mutation in the mit
Externí odkaz:
https://doaj.org/article/1e1164b459de47aea3caa8feba51e9b7
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70357 (2013)
Decline of proteasome activity has been reported in mammals, flies and yeasts during aging. In the yeast Saccharomyces cerevisiae, the reduction of proteolysis in stationary phase is correlated with disassembly of the 26S proteasomes into their 20S a
Externí odkaz:
https://doaj.org/article/e13a252032fe4289a9251677919de6fd