Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

Autor: Satoshi Hirakawa, Katharina Krautgasser, Ingrid Raab, Felix Offner, Nicole Huttary, Brigitte Hantusch, Romana Kalt, Hitonari Nosaka, Katalin Nagy-Bojarszky, Susanne Wolbank, Klaus Kaserer, Michael Gnant, Katharina Viola, Sigurd Krieger, Helga Schachner, Sybille Madlener, Michael Detmar, Thomas Keller, Karin Lackner, Margaretha Rudas, Veronika Sexl, Martin Schreiber, Gregor Bartel, Thorsten J. Maier, Sandra Rezar, Georg Krupitza, Alexander Nader, Kari Alitalo, Agnes Davidovits, Sebastian M.B. Nijman, Dieter Steinhilber, Christine Schneckenleithner, Wolfgang Mikulits, Dontscho Kerjaschki, Zsuzsanna Bago-Horvath, Caroline Vonach, Monika Hämmerle, Helmut Dolznig

Publikováno v: Kerjaschki, D, Bago-Horvath, Z, Rudas, M, Sexl, V, Schneckenleithner, C, Wolbank, S, Bartel, G, Krieger, S, Kalt, R, Hantusch, B, Keller, T, Nagy-Bojarszky, K, Huttary, N, Raab, I, Lackner, K, Krautgasser, K, Schachner, H, Kaserer, K, Rezar, S, Madlener, S, Vonach, C, Davidovits, A, Nosaka, H, Hämmerle, M, Viola, K, Dolznig, H, Schreiber, M, Nader, A, Mikulits, W, Gnant, M, Hirakawa, S, Detmar, M, Alitalo, K, Nijman, S, Offner, F, Maier, T, Steinhilber, D & Krupitza, G 2011, ' Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse ', Journal of Clinical Investigation, vol. 121, no. 5, pp. 2000-12 . https://doi.org/10.1172/JCI44751

In individuals with mammary carcinoma, the most relevant prognostic predictor of distant organ metastasis and clinical outcome is the status of axillary lymph node metastasis. Metastases form initially in axillary sentinel lymph nodes and progress vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af8be4a35185fe0d6b517ce528129b6
https://doi.org/10.1172/jci44751

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro

Autor: Trimurtulu Golakoti, Sibylle Madlener, Somepalli Venkateswarlu, C. Vonach, Monika Fritzer-Szekeres, Benedikt Giessrigl, Nicole Stark, Manuela Gridling, Georg Krupitza, Philipp Saiko, Silvana Geleff, Nicole Huttary, K. Viola, Ruxandra Popescu, Thomas Szekeres, Irene Herbacek, Wolfgang Mikulits, Dontscho Kerjaschki, Michael Grusch, N. T. P. Vo, Agnes Davidovits, Walter Jäger

Publikováno v: British Journal of Cancer

Background: Digalloyl-resveratrol (di-GA) is a synthetic compound aimed to combine the biological effects of the plant polyhydroxy phenols gallic acid and resveratrol, which are both radical scavengers and cyclooxygenase inhibitors exhibiting antican

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa613894665083f4f0ec3807575acf4
https://pubmed.ncbi.nlm.nih.gov/20424615

The carcinoembryonic antigen (CEA) in carcinomata of the stomach

Autor: J. Heinrich Holzner, Agnes Davidovits, Helmut Denk, G. Tappeiner

Publikováno v: Virchows Archiv. A, Pathology. Pathologische Anatomie. 360(4)

The localization of CEA in gastric carcinomata of different histological types was studied by indirect immunofluorescence. In well differentiated adenocarcinomata CEA was present on the surface of the tumor cells. CEA was absent in anaplastic cancers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e68a1d9fd8edcfbb64b554e4956318c
https://pubmed.ncbi.nlm.nih.gov/4355814