Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Agnes Cheong"'
Autor:
Ross C. Gruber, Gregory S. Wirak, Anna S. Blazier, Lan Lee, Michael R. Dufault, Nellwyn Hagan, Nathalie Chretien, Michael LaMorte, Timothy R. Hammond, Agnes Cheong, Sean K. Ryan, Andrew Macklin, Mindy Zhang, Nilesh Pande, Evis Havari, Timothy J. Turner, Anthony Chomyk, Emilie Christie, Bruce D. Trapp, Dimitry Ofengeim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neuroinflammation in the central nervous system (CNS), driven largely by resident phagocytes, has been proposed as a significant contributor to disability accumulation in multiple sclerosis (MS) but has not been addressed therapeutically. Br
Externí odkaz:
https://doaj.org/article/7240258f9fe44a898fcf295ec6f91164
Autor:
Agnes Cheong, Florin Craciun, Hervé Husson, Joseph Gans, Javier Escobedo, Yi-Chien Chang, Lilu Guo, Mariana Goncalves, Nathan Kaplan, Laurie A. Smith, Sarah Moreno, Joseph Boulanger, Shiguang Liu, Jacqueline Saleh, Mindy Zhang, Anna S. Blazier, Weiliang Qiu, Andrew Macklin, Tejaswi Iyyanki, Clément Chatelain, Shameer Khader, Thomas A. Natoli, Oxana Ibraghimov-Beskrovnaya, Dimitry Ofengeim, Jonathan D. Proto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract While significant advances have been made in understanding renal pathophysiology, less is known about the role of glycosphingolipid (GSL) metabolism in driving organ dysfunction. Here, we used a small molecule inhibitor of glucosylceramide s
Externí odkaz:
https://doaj.org/article/68828197b6744988a8444a603fea8bde
Autor:
Alexandria C. Wells, Kaito A. Hioki, Constance C. Angelou, Adam C. Lynch, Xueting Liang, Daniel J. Ryan, Iris Thesmar, Saule Zhanybekova, Saulius Zuklys, Jacob Ullom, Agnes Cheong, Jesse Mager, Georg A. Hollander, Elena L. Pobezinskaya, Leonid A. Pobezinsky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The success of the CD8 T cell-mediated immune response against infections and tumors depends on the formation of a long-lived memory pool, and the protection of effector cells from exhaustion. The advent of checkpoint blockade therapy has si
Externí odkaz:
https://doaj.org/article/91894239e4cb479a9f76d823674243ce
Autor:
Ross Gruber, Anna Blazier, Lan Lee, Sean Ryan, Agnes Cheong, Evis Havari, Timothy Turner, Dimitry Ofengeim
Publikováno v:
Sunday, April 23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2372ab5c3d08f9009d14a8ae0ddd233
https://doi.org/10.1212/wnl.0000000000202142
https://doi.org/10.1212/wnl.0000000000202142
Autor:
Vineetha Mathew, Ariel Mei, Hamida Giwa, Agnes Cheong, Ashmita Chander, Aaron Zou, Robert M. Blanton, Olga Kashpur, Wei Cui, Donna Slonim, Taysir Mahmoud, Perrie O'Tierney-Ginn, Jesse Mager, Isabelle Draper, Mary C. Wallingford
Publikováno v:
Gene Expression Patterns. 48:119319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bdf080e6be92f2664e37578ee0396a5
https://doi.org/10.1016/j.gep.2023.119319
https://doi.org/10.1016/j.gep.2023.119319
Publikováno v:
Dev Biol
Protein phosphatases regulate a wide array of proteins through post-translational modification and are required for a plethora of intracellular events in eukaryotes. While some core components of the protein phosphatase complexes are well characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629a17d6f80c62b4a87ddabc131d1927
https://doi.org/10.1016/j.ydbio.2020.06.011
https://doi.org/10.1016/j.ydbio.2020.06.011
Autor:
Rinat Degani, Agnes Cheong, Jesse Mager, Danielle Archambault, Kimberly D. Tremblay, Elizabeth Iverson
Publikováno v:
Development
Mitochondria are essential for energy production and although they have their own genome, many nuclear-encoded mitochondrial ribosomal proteins (MRPs) are required for proper function of the organelle. Although mutations in MRPs have been associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196eb65e355dba8dfe0d094a27896051
https://europepmc.org/articles/PMC7272334/
https://europepmc.org/articles/PMC7272334/
Autor:
Yuran Tsuchida, Wei Cui, Agnes Cheong, Yong Liu, Jesse Mager, Yongsheng Wang, Kimberly D. Tremblay
Publikováno v:
Reproduction
Microspherule protein 1 (MCRS1, also known as MSP58) is an evolutionarily conserved protein that has been implicated in various biological processes. Although a variety of functions have been attributed to MCRS1 in vitro, mammalian MCRS1 has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2bd9d802fdc0e2c70f7cca779f3a04
https://pubmed.ncbi.nlm.nih.gov/31671403
https://pubmed.ncbi.nlm.nih.gov/31671403
Publikováno v:
Hum Mol Genet
The dynein axonemal assembly factor (Dnaaf) protein family is involved in preassembly and stability of dynein arms before they are transported into the cilia. In humans, mutations in DNAAF genes lead to several diseases related to cilia defects such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33096e75520196655f77e353d5dd97c
https://pubmed.ncbi.nlm.nih.gov/31107948
https://pubmed.ncbi.nlm.nih.gov/31107948
Publikováno v:
Gene Expr Patterns
Mitochondrial ribosomal proteins (MRPs) are essential components for the structural and functional integrity of the mitoribosome complex. Throughout evolution, the mammalian mitoribosome has acquired new Mrp genes to compensate for loss of ribosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac89ad2da0a7e6e76861417228d5835
https://doi.org/10.1016/j.gep.2020.119147
https://doi.org/10.1016/j.gep.2020.119147