Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Agnes, Görlach"'
Autor:
Anna B. Meier, Sarala Raj Murthi, Hilansi Rawat, Christopher N. Toepfer, Gianluca Santamaria, Manuel Schmid, Elisa Mastantuono, Thomas Schwarzmayr, Riccardo Berutti, Julie Cleuziou, Peter Ewert, Agnes Görlach, Karin Klingel, Karl-Ludwig Laugwitz, Christine E. Seidman, Jonathan G. Seidman, Alessandra Moretti, Cordula M. Wolf
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103596- (2022)
Summary: Childhood-onset myocardial hypertrophy and cardiomyopathic changes are associated with significant morbidity and mortality in early life, particularly in patients with Noonan syndrome, a multisystemic genetic disorder caused by autosomal dom
Externí odkaz:
https://doaj.org/article/ed0a2036e5be4bbba4144dc8f1dc2f9b
Autor:
Damir Kračun, Mathieu Klop, Anna Knirsch, Andreas Petry, Ivan Kanchev, Karel Chalupsky, Cordula M. Wolf, Agnes Görlach
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101536- (2020)
Cardiovascular side effects are frequent problems accompanying systemic glucocorticoid therapy, although the underlying mechanisms are not fully resolved. Reactive oxygen species (ROS) have been shown to promote various cardiovascular diseases althou
Externí odkaz:
https://doaj.org/article/a4f07484a45345499585bb06c18b0fa4
Autor:
Javier Egea, Isabel Fabregat, Yves M. Frapart, Pietro Ghezzi, Agnes Görlach, Thomas Kietzmann, Kateryna Kubaichuk, Ulla G. Knaus, Manuela G. Lopez, Gloria Olaso-Gonzalez, Andreas Petry, Rainer Schulz, Jose Vina, Paul Winyard, Kahina Abbas, Opeyemi S. Ademowo, Catarina B. Afonso, Ioanna Andreadou, Haike Antelmann, Fernando Antunes, Mutay Aslan, Markus M. Bachschmid, Rui M. Barbosa, Vsevolod Belousov, Carsten Berndt, David Bernlohr, Esther Bertrán, Alberto Bindoli, Serge P. Bottari, Paula M. Brito, Guia Carrara, Ana I. Casas, Afroditi Chatzi, Niki Chondrogianni, Marcus Conrad, Marcus S. Cooke, João G. Costa, Antonio Cuadrado, Pham My-Chan Dang, Barbara De Smet, Bilge Debelec–Butuner, Irundika H.K. Dias, Joe Dan Dunn, Amanda J. Edson, Mariam El Assar, Jamel El-Benna, Péter Ferdinandy, Ana S. Fernandes, Kari E. Fladmark, Ulrich Förstermann, Rashid Giniatullin, Zoltán Giricz, Anikó Görbe, Helen Griffiths, Vaclav Hampl, Alina Hanf, Jan Herget, Pablo Hernansanz-Agustín, Melanie Hillion, Jingjing Huang, Serap Ilikay, Pidder Jansen-Dürr, Vincent Jaquet, Jaap A. Joles, Balaraman Kalyanaraman, Danylo Kaminskyy, Mahsa Karbaschi, Marina Kleanthous, Lars-Oliver Klotz, Bato Korac, Kemal Sami Korkmaz, Rafal Koziel, Damir Kračun, Karl-Heinz Krause, Vladimír Křen, Thomas Krieg, João Laranjinha, Antigone Lazou, Huige Li, Antonio Martínez-Ruiz, Reiko Matsui, Gethin J. McBean, Stuart P. Meredith, Joris Messens, Verónica Miguel, Yuliya Mikhed, Irina Milisav, Lidija Milković, Antonio Miranda-Vizuete, Miloš Mojović, María Monsalve, Pierre-Alexis Mouthuy, John Mulvey, Thomas Münzel, Vladimir Muzykantov, Isabel T.N. Nguyen, Matthias Oelze, Nuno G. Oliveira, Carlos M. Palmeira, Nikoletta Papaevgeniou, Aleksandra Pavićević, Brandán Pedre, Fabienne Peyrot, Marios Phylactides, Gratiela G. Pircalabioru, Andrew R. Pitt, Henrik E. Poulsen, Ignacio Prieto, Maria Pia Rigobello, Natalia Robledinos-Antón, Leocadio Rodríguez-Mañas, Anabela P. Rolo, Francis Rousset, Tatjana Ruskovska, Nuno Saraiva, Shlomo Sasson, Katrin Schröder, Khrystyna Semen, Tamara Seredenina, Anastasia Shakirzyanova, Geoffrey L. Smith, Thierry Soldati, Bebiana C. Sousa, Corinne M. Spickett, Ana Stancic, Marie José Stasia, Holger Steinbrenner, Višnja Stepanić, Sebastian Steven, Kostas Tokatlidis, Erkan Tuncay, Belma Turan, Fulvio Ursini, Jan Vacek, Olga Vajnerova, Kateřina Valentová, Frank Van Breusegem, Lokman Varisli, Elizabeth A. Veal, A. Suha Yalçın, Olha Yelisyeyeva, Neven Žarković, Martina Zatloukalová, Jacek Zielonka, Rhian M. Touyz, Andreas Papapetropoulos, Tilman Grune, Santiago Lamas, Harald H.H.W. Schmidt, Fabio Di Lisa, Andreas Daiber
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 94-162 (2017)
The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated t
Externí odkaz:
https://doaj.org/article/637c0e34ca5240b4924d5b20463b39fc
Autor:
Stefan Burdach, Günther H.S. Richter, Elke Butt, Andrea Cossarizza, Agnes Görlach, Olivia Prazeres da Costa, Albert Sickmann, Urs Lewandrowski, Katharina Lohrig, Colette Zobywalski, Carsten Müller-Tidow, Rebekka Unland, Frauke Neff, Patricia da Silva-Buttkus, Uwe Thiel, Kristina Hauer, Stephanie Plehm, Irene Esposito, Isabel Diebold, Thomas G.P. Grunewald
PDF file - 621K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac515f338a8df0f2b23504d350f89d9
https://doi.org/10.1158/1541-7786.22517596.v1
https://doi.org/10.1158/1541-7786.22517596.v1
Autor:
Stefan Burdach, Günther H.S. Richter, Elke Butt, Andrea Cossarizza, Agnes Görlach, Olivia Prazeres da Costa, Albert Sickmann, Urs Lewandrowski, Katharina Lohrig, Colette Zobywalski, Carsten Müller-Tidow, Rebekka Unland, Frauke Neff, Patricia da Silva-Buttkus, Uwe Thiel, Kristina Hauer, Stephanie Plehm, Irene Esposito, Isabel Diebold, Thomas G.P. Grunewald
Ewing tumors comprise the second most common type of bone-associated cancer in children and are characterized by oncogenic EWS/FLI1 fusion proteins and early metastasis. Compelling evidence suggests that elevated levels of intracellular oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fb4ff581cd74645a62434114fb1608
https://doi.org/10.1158/1541-7786.c.6541777
https://doi.org/10.1158/1541-7786.c.6541777
Autor:
Andreas Petry, Rupert Öllinger, Thomas G. P. Grunewald, Stefan Burdach, Gaurav Jain, Davide G. Franchina, Erik Hameister, Agnes Görlach, Poul H. Sorensen, Michaela Carina Baldauf, Juliane Schmäh, Jürgen Ruland, Carolin Prexler, Elmar Wolf, Gunther Richter, Dirk Brenner, Alexandra Sipol, Uwe Thiel, Roland Rad, Gunnar Cario, Maxim Barenboim, Julia Hofstetter, Busheng Xue, Rebeca Alba Rubio
Publikováno v:
Sipol, A, Hameister, E, Xue, B, Hofstetter, J, Barenboim, M, Öllinger, R, Jain, G, Prexler, C, Rubio, R A, Baldauf, M C, Franchina, D G, Petry, A, Schmäh, J, Thiel, U, Görlach, A, Cario, G, Brenner, D, Richter, G H S, Grünewald, T G P, Rad, R, Wolf, E, Ruland, J, Sorensen, P H & Burdach, S E G 2022, ' MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress ', Blood, vol. 139, no. 8, pp. 1184-1197 . https://doi.org/10.1182/blood.2020007932
Cancer cells are in most instances characterized by rapid proliferation and uncontrolled cell division. Hence, they must adapt to proliferation-induced metabolic stress through intrinsic or acquired antimetabolic stress responses to maintain homeosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e550109e1f81b852e1a097e196ce3e
https://doi.org/10.1182/blood.2020007932
https://doi.org/10.1182/blood.2020007932
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 275-289 (2015)
Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. In addition, classical regulation of gene expression
Externí odkaz:
https://doaj.org/article/b30442894d004871985dabc11ea42983
Neutrophil 'plucking' on megakaryocytes drives platelet production and boosts cardiovascular disease
Autor:
Tobias Petzold, Zhe Zhang, Iván Ballesteros, Inas Saleh, Amin Polzin, Manuela Thienel, Lulu Liu, Qurrat Ul Ain, Vincent Ehreiser, Christian Weber, Badr Kilani, Pontus Mertsch, Jeremias Götschke, Sophie Cremer, Wenwen Fu, Michael Lorenz, Hellen Ishikawa-Ankerhold, Elisabeth Raatz, Shaza El-Nemr, Agnes Görlach, Esther Marhuenda, Konstantin Stark, Joachim Pircher, David Stegner, Christian Gieger, Marc Schmidt-Supprian, Florian Gaertner, Isaac Almendros, Malte Kelm, Christian Schulz, Andrés Hidalgo, Steffen Massberg
Publikováno v:
Immunity
Immunity 55, 2285-2299.e7 (2022)
Immunity 55, 2285-2299.e7 (2022)
Intravascular neutrophils and platelets collaborate in maintaining host integrity, but their interaction can also trigger thrombotic complications. We report here that cooperation between neutrophil and platelet lineages extends to the earliest stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1ce79743d374a233eb21cb6f1c69ae
https://pubmed.ncbi.nlm.nih.gov/36272416
https://pubmed.ncbi.nlm.nih.gov/36272416
Autor:
Peter Ewert, Cordula M Wolf, Julia Schleihauf, Agnes Görlach, Kathrin Pollmann, Emanuel Kaltenecker
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 22
Journal of Clinical Medicine, Vol 10, Iss 5256, p 5256 (2021)
Volume 10
Issue 22
Journal of Clinical Medicine, Vol 10, Iss 5256, p 5256 (2021)
Hypertrophic cardiomyopathy (HCM) is associated with adverse left ventricular (LV) remodeling causing dysfunction and malignant arrhythmias. Severely affected patients present with disease onset during childhood and sudden cardiac death risk (SCD) st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d282f6380f9405186e5e5bd1957cf73
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122002 (2015)
NADPH oxidases are important sources of reactive oxygen species (ROS) which act as signaling molecules in the regulation of protein expression, cell proliferation, differentiation, migration and cell death. The NOX1 subunit is over-expressed in sever
Externí odkaz:
https://doaj.org/article/bcfc4826922948ebab83426307985fc3