Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Agne, Antanaviciute"'
Autor:
Praveen Weeratunga, Laura Denney, Joshua A. Bull, Emmanouela Repapi, Martin Sergeant, Rachel Etherington, Chaitanya Vuppussetty, Gareth D. H. Turner, Colin Clelland, Jeongmin Woo, Amy Cross, Fadi Issa, Carlos Eduardo de Andrea, Ignacio Melero Bermejo, David Sims, Simon McGowan, Yasemin-Xiomara Zurke, David J. Ahern, Eddie C. Gamez, Justin Whalley, Duncan Richards, Paul Klenerman, Claudia Monaco, Irina A. Udalova, Tao Dong, Agne Antanaviciute, Graham Ogg, Julian C. Knight, Helen M. Byrne, Stephen Taylor, Ling-Pei Ho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Single cell spatial interrogation of the immune-structural interactions in COVID −19 lungs is challenging, mainly because of the marked cellular infiltrate and architecturally distorted microstructure. To address this, we develop a suite o
Externí odkaz:
https://doaj.org/article/b67c218489ea4de7bab095865d7c0ef0
Autor:
Chloe H. Lee, Jaesung Huh, Paul R. Buckley, Myeongjun Jang, Mariana Pereira Pinho, Ricardo A. Fernandes, Agne Antanaviciute, Alison Simmons, Hashem Koohy
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background T-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining tolerance against self-antigens, which has sparked interest in the development of various T-ce
Externí odkaz:
https://doaj.org/article/e4fa26aaefb94dcb8391be6331e31555
Autor:
Anna Aulicino, Agne Antanaviciute, Joe Frost, Ana Sousa Geros, Esther Mellado, Moustafa Attar, Marta Jagielowicz, Philip Hublitz, Julia Sinz, Lorena Preciado-Llanes, Giorgio Napolitani, Rory Bowden, Hashem Koohy, Hal Drakesmith, Alison Simmons
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Aulicino, Antanaviciute et al investigate the transcriptional response to invasive Salmonella strains in dendritic cells (DCs). They show that S. Typhi mount a response against nitrosative stress pathways and propose a role of iron uptake and transpo
Externí odkaz:
https://doaj.org/article/26c225ac2f684651825e4bab14553e42
Autor:
Antonios Psarras, Adewonuola Alase, Agne Antanaviciute, Ian M. Carr, Md Yuzaiful Md Yusof, Miriam Wittmann, Paul Emery, George C. Tsokos, Edward M. Vital
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Type I interferon drives autoimmune pathology in SLE and has been assumed to come predominantly from plasmacytoid dendritic cells (pDCs). Here, the authors show that prior to the onset of SLE, pDCs lose multiple immunogenic functions and, instead, no
Externí odkaz:
https://doaj.org/article/bbb2318833484129bd8e0fdec78640c3
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100890- (2021)
Summary: The intestine has a large number of cell types. Thus, digestion of pure and viable populations is necessary for downstream techniques including single-cell RNA sequencing. We outline a protocol to isolate both epithelial and non-epithelial c
Externí odkaz:
https://doaj.org/article/9e5f1ac9e43b4ca9a5909fa194fd40ff
Autor:
Christine Harnack, Hilmar Berger, Agne Antanaviciute, Ramon Vidal, Sascha Sauer, Alison Simmons, Thomas F. Meyer, Michael Sigal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Epithelial turnover in the colon requires stem cells in the crypt that express the R-spondin receptor Lgr5. Here, the authors show that regeneration after colon injury involving loss of Lgr5+ and Axin2+ cells requires stromal derived Rspo3-dependent
Externí odkaz:
https://doaj.org/article/92a90fca25a047f5b37a3718152ed773
Autor:
Emily Fraser, Laura Denney, Agne Antanaviciute, Karl Blirando, Chaitanya Vuppusetty, Yuejuan Zheng, Emmanouela Repapi, Valentina Iotchkova, Stephen Taylor, Neil Ashley, Victoria St Noble, Rachel Benamore, Rachel Hoyles, Colin Clelland, Joseph M. D. Rastrick, Clare S. Hardman, Nasullah K. Alham, Rachel E. Rigby, Alison Simmons, Jan Rehwinkel, Ling-Pei Ho
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Idiopathic pulmonary fibrosis (IPF) is the most severe form of chronic lung fibrosis. Circulating monocytes have been implicated in immune pathology in IPF but their phenotype is unknown. In this work, we determined the immune phenotype of monocytes
Externí odkaz:
https://doaj.org/article/2bf92ce74a22443b86f715dc1150d4d6
Autor:
Belinda Baquero-Perez, Agne Antanaviciute, Ivaylo D Yonchev, Ian M Carr, Stuart A Wilson, Adrian Whitehouse
Publikováno v:
eLife, Vol 8 (2019)
N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and translation. Using an m6A-modif
Externí odkaz:
https://doaj.org/article/8f45fcf9731d40a1852c8fa1a6403483
Autor:
Paul R. Buckley, Chloe H. Lee, Mariana Pereira Pinho, Rosana Ottakandathil Babu, Jeongmin Woo, Agne Antanaviciute, Alison Simmons, Graham Ogg, Hashem Koohy
Publikováno v:
Immunology. 166:78-103
Publikováno v:
Immunotherapy Advances. 3
T cell recognition of SARS-CoV-2 antigens after vaccination and/or natural infection has played a central role in resolving SARS-CoV-2 infections and generating adaptive immune memory. However, the clinical impact of SARS-CoV-2-specific T cell respon