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Akademický článek

Mathematical modeling of the thermal effects of irreversible electroporation for in vitro, in vivo, and clinical use: a systematic review

Autor: Pierre Agnass, Eran van Veldhuisen, Martin J. C. van Gemert, Cees W. M. van der Geld, Krijn P. van Lienden, Thomas M. van Gulik, Martijn R. Meijerink, Marc G. Besselink, H. Petra Kok, Johannes Crezee

Publikováno v: International Journal of Hyperthermia, Vol 37, Iss 1, Pp 486-505 (2020)

Introduction Irreversible electroporation (IRE) is a relatively new ablation method for the treatment of unresectable cancers. Although the main mechanism of IRE is electric permeabilization of cell membranes, the question is to what extent thermal e

Externí odkaz: https://doaj.org/article/32bd84cd2df445f4ad9766615146f5b0

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Akademický článek

Improving Prediction of the Potential Distribution Induced by Cylindrical Electrodes within a Homogeneous Rectangular Grid during Irreversible Electroporation

Autor: Pierre Agnass, Krijn P. van Lienden, Thomas M. van Gulik, Marc G. Besselink, Johannes Crezee, H. Petra Kok

Publikováno v: Applied Sciences, Vol 12, Iss 3, p 1471 (2022)

Background: Irreversible electroporation (IRE) is an ablation technique based on the application of short, high-voltage pulses between needle electrodes (diameter: ~1.0 × 10−3 m). A Finite Difference-based software simulating IRE treatment general

Externí odkaz: https://doaj.org/article/78fb29eaf49949a4911998f116a2d1e1

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Akademický článek

HyCHEED System for Maintaining Stable Temperature Control during Preclinical Irreversible Electroporation Experiments at Clinically Relevant Temperature and Pulse Settings

Autor: Pierre Agnass, Hans M. Rodermond, Remko Zweije, Jan Sijbrands, Jantien A. Vogel, Krijn P. van Lienden, Thomas M. van Gulik, Eran van Veldhuisen, Nicolaas A. P. Franken, Arlene L. Oei, H. Petra Kok, Marc G. Besselink, Johannes Crezee

Publikováno v: Sensors, Vol 20, Iss 21, p 6227 (2020)

Electric permeabilization of cell membranes is the main mechanism of irreversible electroporation (IRE), an ablation technique for treatment of unresectable cancers, but the pulses also induce a significant temperature increase in the treated volume.

Externí odkaz: https://doaj.org/article/3979814dcb8648c6bdaecbbc5a3f827e

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Akademický článek

Correction: Time-Dependent Impact of Irreversible Electroporation on Pancreas, Liver, Blood Vessels and Nerves: A Systematic Review of Experimental Studies.

Autor: J A Vogel, E van Veldhuisen, P Agnass, J Crezee, F Dijk, J Verheij, T M van Gulik, M R Meijerink, L G Vroomen, K P van Lienden, M G Besselink

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0174018 (2017)

[This corrects the article DOI: 10.1371/journal.pone.0166987.].

Externí odkaz: https://doaj.org/article/d6a029bd8ea04db5b6bd75064473d7af

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Akademický článek

Time-Dependent Impact of Irreversible Electroporation on Pancreas, Liver, Blood Vessels and Nerves: A Systematic Review of Experimental Studies.

Autor: J A Vogel, E van Veldhuisen, P Agnass, J Crezee, F Dijk, J Verheij, T M van Gulik, M R Meijerink, L G Vroomen, K P van Lienden, M G Besselink

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0166987 (2016)

Irreversible electroporation (IRE) is a novel ablation technique in the treatment of unresectable cancer. The non-thermal mechanism is thought to cause mostly apoptosis compared to necrosis in thermal techniques. Both in experimental and clinical stu

Externí odkaz: https://doaj.org/article/e14bdabfa28d4ac288e08e59ceb78049

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