Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Agnès Rioux Bilan"'
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 5, Pp 843-849 (2020)
Alzheimer’s disease is one of the most frequent neurodegenerative diseases. This pathology is characterized by protein aggregates, mainly constituted by amyloid peptide and tau, leading to neuronal death and cognitive impairments. Drugs currently p
Externí odkaz:
https://doaj.org/article/f92bc98b5fdd4e9fa2570943b95ba580
Autor:
Aline Freyssin, Agnès Rioux Bilan, Bernard Fauconneau, Laurent Galineau, Sophie Serrière, Clovis Tauber, Flavie Perrin, Jérôme Guillard, Sylvie Chalon, Guylène Page
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
In a previous study, we showed that viniferin decreased amyloid deposits and reduced neuroinflammation in APPswePS1dE9 transgenic mice between 3 and 6 months of age. In the present study, wild type and APPswePS1dE9 transgenic mice were treated from 7
Externí odkaz:
https://doaj.org/article/958d284ccdea4b54b097fbf6af9dfd35
Natural polyphenols effects on protein aggregates in Alzheimer's and Parkinson's prion-like diseases
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 6, Pp 955-961 (2018)
Alzheimer's and Parkinson's diseases are the most common neurodegenerative diseases. They are characterized by protein aggregates and so can be considered as prion-like disease. The major components of these deposits are amyloid peptide and tau for A
Externí odkaz:
https://doaj.org/article/c3a9a512f8954fea8c0dd3e371ee1dfa
Trans ε viniferin decreases amyloid deposits and inflammation in a mouse transgenic Alzheimer model.
Autor:
Martial Caillaud, Jérôme Guillard, Damien Richard, Serge Milin, Damien Chassaing, Marc Paccalin, Guylène Page, Agnès Rioux Bilan
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212663 (2019)
As Alzheimer's disease (AD) induces several cellular and molecular damages, it could be interesting to use multi-target molecules for therapeutics. We previously published that trans ε-viniferin induced the disaggregation of Aβ42 peptide and inhibi
Externí odkaz:
https://doaj.org/article/6104f88045bb463db21808ccbf871d92
Autor:
Milena Damjanac, Agnès Rioux Bilan, Marc Paccalin, Raymond Pontcharraud, Bernard Fauconneau, Jacques Hugon, Guylène Page
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 2, Pp 354-367 (2008)
Previous studies demonstrated that the PKR (double-stranded RNA-activated protein kinase) pathway was activated while the mTOR (mammalian target of rapamycin) pathway was inhibited in Alzheimer’s disease (AD). Here, we analysed upstream and downstr
Externí odkaz:
https://doaj.org/article/26ca3103c46e4b42b2c5104c2ef2feba
Publikováno v:
Drug and Chemical Toxicology. 45:1995-2002
In vivo treatment of hydrophobic substances requires the use of organic solvents, which are often toxic. Consequently, polyethylene glycols (PEGs), which are considered as nontoxic, have been widely used for many years in chemistry and biology. We us
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 5, Pp 843-849 (2020)
Neural Regeneration Research
Neural Regeneration Research
Alzheimer's disease is one of the most frequent neurodegenerative diseases. This pathology is characterized by protein aggregates, mainly constituted by amyloid peptide and tau, leading to neuronal death and cognitive impairments. Drugs currently pro
Autor:
Thierry Dantoine, Marc Paccalin, Guylène Page, Pierre Krolak-Salmon, Caroline Hommet, Gilles Berrut, Stéphanie Ragot, Adrien Julian, Olivier Hanon, Agnès Rioux-Bilan
Publikováno v:
Journal of Alzheimer's Disease. 63:87-92
Peripheral inflammatory processes are involved in Alzheimer's disease (AD). We aimed to determine whether plasma inflammatory mediator levels at diagnosis are associated with cognitive decline through a 2-year follow-up in AD patients. Patients (n =
Publikováno v:
Molecular and Cellular Neuroscience. 88:1-6
Alzheimer's disease (AD) is marked by several cellular and molecular damage. Therefore, the therapeutic interest of multi-target molecules is increasingly justified. Polyphenols presenting multiple pharmacological effects would be more efficient. In
Autor:
Marc Paccalin, Thierry Janet, Julie Verite, Agnès Rioux Bilan, Arnaud François, Bernard Fauconneau, Frédéric Calon, Guylène Page
Neurodegenerative disorders are characterized by progressive accumulation of aggregated and misfolded proteins, brain inflammation, autophagy impairment, and metabolism disturbances associated with cognitive and/or physical declines. However, no ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0403100cd497046fb314da2d3e84ab7e
https://doi.org/10.1016/b978-0-12-802733-2.00011-6
https://doi.org/10.1016/b978-0-12-802733-2.00011-6