Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis

Autor: Aline Mariage, Agnès Pinet-Turpault, Antoine Danchin, Ekaterina Darii, Véronique de Berardinis, Claudine Médigue, Carine Vergne-Vaxelaire, Anne Zaparucha, François Artiguenave, Clémence Brewee, David Vallenet, Thomas Bessonnet, Jean-Louis Petit, Pascal Bazire, Jean Weissenbach, Marcel Salanoubat, Virginie Pellouin, Marielle Besnard-Gonnet, Alain Perret, Adrien Debard, Karine Bastard

Publikováno v: Nature Chemical Biology
Nature Chemical Biology, 2017, 13, pp.858-866. ⟨10.1038/nchembio.2397⟩
Nature Chemical Biology, Nature Publishing Group, 2017, 13, pp.858-866. ⟨10.1038/nchembio.2397⟩

MetA and MetX are phylogenetically unrelated families of acyl-L-homoserine transferases. Experimental assignation of function and structural modeling of these families correct widespread misannotation, reveal convergence of function and uncover new f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e841a846becb3deb21c9a29422f9b335
https://pubmed.ncbi.nlm.nih.gov/28926556