CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Autor: Andrew E. Prendergast, Kin Ki Jim, Hugo Marnas, Laura Desban, Feng B. Quan, Lydia Djenoune, Valerio Laghi, Agnès Hocquemiller, Elias T. Lunsford, Julian Roussel, Ludovic Keiser, Francois-Xavier Lejeune, Mahalakshmi Dhanasekar, Pierre-Luc Bardet, Jean-Pierre Levraud, Diederik van de Beek, Christina M.J.E. Vandenbroucke-Grauls, Claire Wyart

Publikováno v: Current Biology-CB
Current Biology-CB, 2023, 33 (5), pp.940-956.e10. ⟨10.1016/j.cub.2023.01.039⟩
Current Biology, 33(5), 940-956.e10. Cell Press
Current biology, 33(5), 940-956.e10. Cell Press
Prendergast, A E, Jim, K K, Marnas, H, Desban, L, Quan, F B, Djenoune, L, Laghi, V, Hocquemiller, A, Lunsford, E T, Roussel, J, Keiser, L, Lejeune, F-X, Dhanasekar, M, Bardet, P-L, Levraud, J-P, van de Beek, D, Vandenbroucke-Grauls, C M J E & Wyart, C 2023, ' CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection ', Current Biology, vol. 33, no. 5, pp. 940-956.e10 . https://doi.org/10.1016/j.cub.2023.01.039

International audience; The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether and how sensory cells in the central nervous system (CNS) b

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