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pro vyhledávání: '"Agnès Costaz"'
Autor:
Delphine Delannée, Agnès Costaz, Jonathan Thomas Seal, Lionel Trottet, Rémi Tellier, Jean-Marie Brusq, Olivier Mirguet, Anne Marie Jeanne Bouillot, Sandrine Martin, Gael Krysa, Anne-Benedicte Boullay, Jorge Kirilovsky, Eric Boursier, Jérôme Toum, Yann Dudit, Van-Loc Nguyen, Edwige Nicodeme, Françoise Gellibert, Alizon M. Riou, Pascal Huet, Romain Luc Marie Gosmini, Yann Lamotte, Florence Blandel, Frédéric Donche
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(8)
The discovery, synthesis and biological evaluation of a novel series of 7-isoxazoloquinolines is described. Several analogs are shown to increase ApoA1 expression within the nanomolar range in the human hepatic cell line HepG2.