Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Agnès CONJARD"'
Autor:
Olivia Febvey-Combes, Jérôme Guitton, Perrine Marec-Berard, Cécile Faure-Conter, Ellen Blanc, Sylvie Chabaud, Agnès Conjard-Duplany, Matthias Schell, Laurence Derain Dubourg
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Ifosfamide is a major anti-cancer drug in children with well-known renal toxicity. Understanding the mechanisms underlying this toxicity could help identify children at increased risk of toxicity. Methods The IFOS01 study included
Externí odkaz:
https://doaj.org/article/ce3b1eaa51544e12ab9223cb32a886ff
Publikováno v:
Neuroscience. 248:243-251
To examine the effect of glucose on the cerebral metabolism of glutamine, rat brain slices were incubated with 5 mM [3- 13 C]glutamine without and with 5 mM unlabeled glucose. Tissue plus medium extracts were analyzed by using enzymatic and 13 C NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d810227a98ddc4eaf7344b3374c5187
https://doi.org/10.1016/j.neuroscience.2013.05.064
https://doi.org/10.1016/j.neuroscience.2013.05.064
Publikováno v:
Neurochemistry International. 58:896-903
This study was performed to analyze the metabolic fate of a high concentration (5 mM) of glutamine and glutamate in rat brain slices and the participation of these amino acids in the glutamine–glutamate cycle. For this, brain slices were incubated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed0a68df75dc026bab22bd7d7189378
https://doi.org/10.1016/j.neuint.2011.02.018
https://doi.org/10.1016/j.neuint.2011.02.018
Autor:
Stéphanie Gohin, Laurence Dubourg, Agnès Conjard-Duplany, Jean Louis Saumet, Dominique Sigaudo-Roussel, Bérengère Fromy
Publikováno v:
Journal of Investigative Dermatology. 131(1):237-244
In endothelial function, prostacyclin (PGI(2)) is as important as nitric oxide (NO); however, no test assesses specifically the vascular function of endogenous PGI(2). We hypothesized that PGI(2) has a dominant role in cathodal current-induced vasodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f9c29ddc352370b624fcb10921187d
Autor:
Sophie Renault, Guy Martin, Agnès Conjard-Duplany, Hassan Faiz, Rudy Gadet, Gabriel Baverel, Bernard Ferrier
Publikováno v:
Toxicology and Applied Pharmacology. 242:9-17
As part of a study on uranium nephrotoxicity, we investigated the effect of uranyl nitrate in isolated human and mouse kidney cortex tubules metabolizing the physiological substrate lactate. In the millimolar range, uranyl nitrate reduced lactate rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e7bbecbbfdbdc7c09e93d5ce9d1075
https://doi.org/10.1016/j.taap.2009.09.002
https://doi.org/10.1016/j.taap.2009.09.002
Autor:
Agnès Conjard-Duplany, Guy Martin, Hassan Faiz, Michelle Boghossian, Gabriel Baverel, Bernard Ferrier
Publikováno v:
Toxicology letters. 238(3)
Using isolated mouse renal proximal tubules incubated with lactate as substrate, we have found that the addition of 1-50 μM cadmium chloride (CdCl2) caused a concentration-dependent decrease in lactate utilization, in glucose production and in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e2b07f3fecf04257265878fa2feb7a
https://pubmed.ncbi.nlm.nih.gov/26235813
https://pubmed.ncbi.nlm.nih.gov/26235813
Autor:
Mireille Martin, Jérôme Guitton, Hélène Delage, Agnès Conjard, Michelle Boghossian, Assaad A. Eid, Gabriel Baverel, Bernard Ferrier
Publikováno v:
Archives of Toxicology. 79:587-594
Cephaloridine, which accumulates in the renal proximal tubule, is a model compound used for studying the toxicity of antibiotics towards this nephron segment. Several studies have demonstrated that cephaloridine alters renal intermediary and energy m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb5ff7f2c89757399ac74f8ea5c73d0
https://doi.org/10.1007/s00204-005-0673-5
https://doi.org/10.1007/s00204-005-0673-5
Autor:
Ola Komaty, Gabriel Baverel, Hélène Delage, Agnès Conjard, Bernard Ferrier, Michelle Boghossian, Mireille Martin
Publikováno v:
Journal of Biological Chemistry. 278:38159-38166
As part of a study on the regulation of renal ammoniagenesis in the mouse kidney, we investigated the effect of chronic metabolic acidosis on glutamine synthesis by isolated mouse renal proximal tubules. The results obtained reveal that, in tubules f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d0e1d3ba832e93b309a010237d8bf90
https://doi.org/10.1074/jbc.m302885200
https://doi.org/10.1074/jbc.m302885200
Autor:
Sylvie Dugelay, Guy Martin, Agnès Conjard, Daniel Durozard, Gabriel Baverel, Marie-France Chauvin
Publikováno v:
Journal of Biological Chemistry. 277:29444-29454
Although acetate, the main circulating volatile fatty acid in humans and animals, is metabolized at high rates by the renal tissue, little is known about the precise fate of its carbons and about the regulation of its renal metabolism. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eade7dd46ffcc604cb6c0e2af96461c9
https://doi.org/10.1074/jbc.m111335200
https://doi.org/10.1074/jbc.m111335200
Publikováno v:
Biochemical Journal. 360:371-377
Recent studies in vivo have suggested that, in humans in the postabsorptive state, the kidneys contribute a significant fraction of systemic gluconeogenesis, and that the stimulation of renal gluconeogenesis may fully explain the increase in systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68f9c3ff2b024427f4154dd4d75ce48
https://doi.org/10.1042/bj3600371
https://doi.org/10.1042/bj3600371