Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Aglaia, Athanassiadou"'
Autor:
Hila Avisar, Cristina Guardia-Laguarta, Matthew Surface, Nikos Papagiannakis, Matina Maniati, Roubina Antonellou, Dimitra Papadimitriou, Christos Koros, Aglaia Athanassiadou, Serge Przedborski, Boaz Lerner, Leonidas Stefanis, Estela Area-Gomez, Roy N. Alcalay
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Lipid profiles in biological fluids from patients with Parkinson’s disease (PD) are increasingly investigated in search of biomarkers. However, the lipid profiles in genetic PD remain to be determined, a gap of knowledge of particular inte
Externí odkaz:
https://doaj.org/article/83b6cfbe26d145959efe4f680aa04238
Autor:
Eleana F. Stavrou, Marxa L. Figueiredo, Virgínia Picanço-Castro, Aglaia Athanassiadou, Grace E. Mulia
Publikováno v:
Human Gene Therapy
Nonviral and nonintegrating episomal vectors are reemerging as a valid, alternative technology to integrating viral vectors for gene therapy, due to their more favorable safety profile, significantly lower risk for insertional mutagenesis, and a less
Autor:
Maria-Eleni I Tsitoura, Eleana F Stavrou, Ioannis A Maraziotis, Kosmas Sarafidis, Aglaia Athanassiadou, Gabriel Dimitriou
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166516 (2016)
Newborns delivered late-preterm (between 340/7 and 366/7 weeks of gestation) are at increased risk of respiratory distress syndrome (RDS). Polymorphisms within the surfactant protein (SP) A and B gene have been shown to predispose to RDS in preterm n
Externí odkaz:
https://doaj.org/article/8f4f99d3525c4ca0a8fdb8eb2efe2ae4
Autor:
V.P.E. Castro, Grace E. Mulia, Dimas Tadeu Covas, GM Aguiar, Marxa L. Figueiredo, Aglaia Athanassiadou, Krs Gomes, Eleana F. Stavrou
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss, Pp S272-S273 (2021)
Aims CAR-T cell therapy has proven its importance in cancer treatment and currently there are five approved products on the market. However, these products are based on viral vectors, which presents a risk of insertional mutagenesis, it can also be i
Autor:
Corinne Marie, Eleana F. Stavrou, Michael Quiviger, Daniel Scherman, Aglaia Athanassiadou, Aristeidis Giannakopoulos, Meletios Verras
Publikováno v:
Molecular Biology Reports
Molecular Biology Reports, Springer Verlag, 2019, 46 (3), pp.3203-3211. ⟨10.1007/s11033-019-04777-9⟩
Molecular Biology Reports, Springer Verlag, 2019, 46 (3), pp.3203-3211. ⟨10.1007/s11033-019-04777-9⟩
International audience; Liver-directed gene therapy, using mainly viral vectors for the genetic cell modification, is a promising therapeutic approach for many genetic and metabolic liver diseases. The recent successful preclinical trials with AAV ve
Autor:
Dimas Tadeu Covas, Geciane Silveira Porto, Virgínia Picanço-Castro, Aglaia Athanassiadou, Cristiano Gonçalves Pereira, Marxa L. Figueiredo
Publikováno v:
Nat Biotechnol
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
An analysis of the emerging patent landscape of gene therapies under development, focusing on non-viral vectors.
Autor:
Aglaia Athanassiadou, Meletios Verras, Emannuouil Simantirakis, Kenneth R. Peterson, Eleana F. Stavrou, Carlos F. Barbas, George Vassilopoulos
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
We report the development of episomal vectors for the specific γ-globin transcription activation in its native position by activator Zif-VP64, based on the Scaffold/Matrix Attachment Region (S/MAR) for episomal retention and the β-globin Replicator
Motor and Nonmotor Features of Carriers of the p.A53T Alpha‐Synuclein Mutation: A Longitudinal Study
Autor:
Nikolaos Papagiannakis, Christos Koros, Elisabeth Kapaki, Dimitra Papadimitriou, Roy N. Alcalay, Maria Stamelou, Athannassios Leonardos, Sokratis G. Papageorgiou, Michael Miligkos, Leonidas Stefanis, Roubina Antonelou, Alexandros Papadimitriou, Athina Simitsi, Aglaia Athanassiadou, Matina Maniati, Sevasti Bostantjopoulou
Publikováno v:
Movement Disorders. 31:1226-1230
Background G209A SNCA mutation carriers represent an important group of genetic PD. We describe motor and nonmotor features of G209A SNCA mutation carriers. Methods Longitudinal clinical assessments over 2 years were collected in 22 symptomatic and 8
Autor:
Mickael Quiviger, Aristeidis Giannakopoulos, Sebastien Verhenne, Karen Vanhoorelbeke, Daniel Scherman, Aglaia Athanassiadou, Zsuzsanna Izsvák, Simon F. De Meyer, Corinne Marie, Eleana F. Stavrou
Publikováno v:
European Journal of Medical Genetics
European Journal of Medical Genetics, 2018, 61 (11), pp.723-728. ⟨10.1016/j.ejmg.2018.04.010⟩
European Journal of Medical Genetics, Elsevier, 2018, 61 (11), pp.723-728. ⟨10.1016/j.ejmg.2018.04.010⟩
European Journal of Medical Genetics, 2018, 61 (11), pp.723-728. ⟨10.1016/j.ejmg.2018.04.010⟩
European Journal of Medical Genetics, Elsevier, 2018, 61 (11), pp.723-728. ⟨10.1016/j.ejmg.2018.04.010⟩
International audience; Many rare monogenic diseases are treated by protein replacement therapy, in which the missing protein is repetitively administered to the patient. However, in several cases, the missing protein is required at a high and sustai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11b3a3591db063964811d13a3649c9b
https://hal-cnrs.archives-ouvertes.fr/hal-03292061
https://hal-cnrs.archives-ouvertes.fr/hal-03292061
Autor:
Eirini P. Papapetrou, Alexandros Spyridonidis, Vassileios M. Lazaris, Aristeidis Giannakopoulos, Nikolas C. Zoumbos, Antonis Gkountis, Aglaia Athanassiadou, Eleana F. Stavrou
Publikováno v:
Scientific Reports
Specific human chromosomal elements enhance the performance of episomal gene-transfer vectors. S/MAR-based episomal vector pEPI-eGFP transfects CD34+ haematopoietic cells, but only transiently. To address this issue we reinforced (1) transgene transc