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of 36
pro vyhledávání: '"Ageing-related disease"'
Akademický článek
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Autor:
Partridge, Linda
Publikováno v:
Philosophical Transactions: Biological Sciences, 2010 Jan 01. 365(1537), 147-154.
Externí odkaz:
https://www.jstor.org/stable/40538169
Akademický článek
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Autor:
Paulo J. Oliveira, Susana P. Pereira, Rodrigo Mello Gomes, Paulo Matafome, Luís F. Grilo, Mariana S. Diniz, Carolina Tocantins
Publikováno v:
European journal of clinical investigationREFERENCES. 51(10)
Embryonic and foetal development are critical periods of development in which several environmental cues determine health and disease in adulthood. Maternal conditions and an unfavourable intrauterine environment impact foetal development and may pro
Akademický článek
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Autor:
Carmela Rita Balistreri, Alexander Koliada, Alexander Vaiserman, Olga Maslova, Elena De Falco
Publikováno v:
Ageing research reviews. 56
Improving healthspan is the main objective of anti-ageing research. Currently, innovative gene therapy-based approaches seem to be among the most promising for preventing and treating chronic polygenic pathologies, including age-related ones. The gen
Autor:
Carmela Rita Balistreri, Paolo Garagnani, Rosalinda Madonna, Alexander Vaiserman, Gerry Melino
Publikováno v:
Ageing Research Reviews. 54:100918
The Barker hypothesis of ‘foetal origin of adult diseases’ has led to emphasize the concept of ‘developmental programming’, based on the crucial role of epigenetic factors. Accordingly, it has been demonstrated that parental adversity (before
Autor:
Elena Radi, Gian Nicola Gallus, Elena Cardaioli, Paola Da Pozzo, Antonio Federico, Patrizia Formichi
Publikováno v:
Journal of the Neurological Sciences. 322:254-262
Mitochondria are involved in ATP supply to cells through oxidative phosphorylation (OXPHOS), synthesis of key molecules and response to oxidative stress, as well as in apoptosis. They contain many redox enzymes and naturally occurring inefficiencies
Autor:
Linda Partridge
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
Human life expectancy in developed countries has increased steadily for over 150 years, through improvements in public health and lifestyle. More people are hence living long enough to suffer age-related loss of function and disease, and there is a n
Autor:
Linda Partridge
Publikováno v:
Trends Endocrinol Metab
Increases in human lifespan worldwide have revealed that advancing age is the predominant risk factor for major life-threatening diseases. Recent work has shown that ageing in diverse animals, including humans, is malleable to specific types of genet