Výsledky vyhledávání - "Age-Related Atrophy"

Akademický článek

Sublinear association between cortical thickness at the onset of the adult lifespan and age-related annual atrophy parallels spatial patterns of laminar organization in the adult cerebral cortex

Autor: Bruno Hebling Vieira, Carlos Ernesto Garrido Salmon

Publikováno v: Neuroimage: Reports, Vol 1, Iss 2, Pp 100011- (2021)

Brain aging is a complex process, entailing alterations at the most diverse levels of brain structure and functioning. On the macroscopical scale, gray matter atrophy is one of its most prominent markers, but it remains to be elucidated why some regi

Externí odkaz: https://doaj.org/article/4100b7887d7f4d6b89e934ef6eadc7bf

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Autor: Marcel R.M. van den Brink, Christopher P. Coplen, Jennifer L. Uhrlaub, Bonnie LaFleur, Sandip Ashok Sonar, Janko Nikolich-Zugich, Mladen Jergović, Gregory D. Sempowski, Jarrod A Dudakov

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 119(17)

Secondary lymphoid organs (SLO; including the spleen and lymph nodes) are critical both for the maintenance of naïve T (TN) lymphocytes and for the initiation and coordination of immune responses. How they age, including the exact timing, extent, ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf2809b1bdf9d64066fba52221075f4
https://pubmed.ncbi.nlm.nih.gov/35439062

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Autor: B. Blair Braden, Marwan N. Sabbagh, Corianne Rogalsky, Megan C. Fitzhugh, Leslie C. Baxter

Publikováno v: Journal of the International Neuropsychological Society. 25:569-582

Objectives: Despite changes to brain integrity with aging, some functions like basic language processes remain remarkably preserved. One theory for the maintenance of function in light of age-related brain atrophy is the engagement of compensatory br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649ba92fcf3dbd835308dfe330422110
https://doi.org/10.1017/s1355617719000274

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Autor: Igor Yakushev, Gregory S. Day, David M. Holtzman, Brian A. Gordon, Clifford R. Jack, Matthew F. Glasser, Richard J. Perrin, Joshua S. Shimony, Pamela LaMontagne, Tammie L.S. Benzinger, Lauren N. Koenig, Jasmeer P. Chhatwal, Catherine J. Mummery, Randall J. Bateman, John C. Morris

Publikováno v: Neurobiol Aging

Brain atrophy occurs in aging even in the absence of dementia, but it is unclear to what extent this is due to undetected preclinical Alzheimer disease. Here we examine a cross-sectional cohort (ages 18-88) free from confounding influence of preclini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e39c145ccd972977271de6cc707d28
https://pubmed.ncbi.nlm.nih.gov/34655980

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Akademický článek

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Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia

Autor: John C. Morris, Nupur Ghoshal, Barbara J. Snider, Massoumazada P, Benzinger Tls, Sarah Keefe, Michelle M. Miller-Thomas, Lauren N. Koenig, Laura M. Marple, Cyrus A. Raji, Joshua S. Shimony, Gregory S. Day, Justin M. Long, Kanthamneni M, Pamela LaMontagne, Brian A. Gordon, Amber Salter

Publikováno v: NeuroImage: Clinical, Vol 26, Iss, Pp-(2020)
NeuroImage : Clinical

Highlights • Volumetric MRI classification models can detect symptomatic Alzheimer disease. • Detection improved by using multiple regions instead of hippocampal volume alone. • Detection not improved by including age or controlling for age-rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4370e5bf4d4f48a8569e84fe2c877af
http://www.sciencedirect.com/science/article/pii/S2213158220300851

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Prolonged caloric restriction ameliorates age-related atrophy in slow and fast muscle fibers of rat soleus muscle

Autor: Naoyuki Okita, Miki Yoshida, Masaki Kobayashi, Hiroki Saito, Yuka Sudo, Akifumi Goto, Hitoshi Shimano, Yuhei Mizunoe, Yoshimi Nakagawa, Ryoma Tagawa, Ai Umemori, Ryota Migitaka, Kumi Miura, Yoshikazu Higami

Publikováno v: Experimental Gerontology. 154:111519

Aging causes loss of skeletal muscle mass and function, which is called sarcopenia. While sarcopenia impairs the quality of life of older adults and is a major factor in long-term hospitalization, its detailed pathogenic mechanism and preventive meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f652cb314c3dfe3f4b1d7aed007a9b1
https://doi.org/10.1016/j.exger.2021.111519

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Bilateral age-related atrophy in the planum temporale is associated with vowel discrimination difficulty in healthy older adults

Autor: Tobias Kleinjung, Benjamin Isler, Martin Meyer, Nathalie Giroud, Sarah Hirsiger

Publikováno v: Hearing Research. 406:108252

In this study we investigated the association between age-related brain atrophy and behavioural as well as electrophysiological markers of vowel perception in a sample of healthy younger and older adults with normal pure-tone hearing. Twenty-three ol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a57f0bfd92e0fa47e0d880daa4dfa33
https://doi.org/10.1016/j.heares.2021.108252

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Examining the identification of age-related atrophy between T1 and T1 + T2-FLAIR cortical thickness measurements

Autor: Rosaleena Mohanty, Veena A. Nair, Robert D. Sanders, Casandra Stanfield, Heidi Lindroth, Cameron Casey, Vivek Prabhakaran, Roger L. Brown, Daniel Wayer, Paul A. Rowley

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Cortical thickness is traditionally derived from T1-weighted MRI images. Recent studies have shown an improvement in segmentation with the combination of T1 + T2-FLAIR images. MRI data from 54 adults (mean: 71 years, 65–81 years, 48% females) that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b3b0330dcdef578cefc250ac93a845
http://europepmc.org/articles/PMC6677836

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Sublinear association between cortical thickness at the onset of the adult lifespan and age-related annual atrophy parallels spatial patterns of laminar organization in the adult cerebral cortex

Autor: Carlos Ernesto Garrido Salmon, Bruno Hebling Vieira

Publikováno v: Neuroimage: Reports, Vol 1, Iss 2, Pp 100011-(2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2453ac9c26de3e86760c1a4e8bb2599f
https://doi.org/10.1016/j.ynirp.2021.100011

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