Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Agback P"'
Autor:
Johan Wallerstein, Xiao Han, Maria Levkovets, Dmitry Lesovoy, Daniel Malmodin, Claudio Mirabello, Björn Wallner, Renhua Sun, Tatyana Sandalova, Peter Agback, Göran Karlsson, Adnane Achour, Tatiana Agback, Vladislav Orekhov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Mucosa-associated lymphoid tissue lymphoma-translocation protein 1 (MALT1) is an attractive target for the development of modulatory compounds in the treatment of lymphoma and other cancers. While the three-dimensional structure of MALT1 has
Externí odkaz:
https://doaj.org/article/884d29c1ed8241afb428cd2113dd173d
Autor:
Qiu, Tianyu, Jahangiri, Amir, Han, Xiao, Lesovoy, Dmitry, Agback, Tatiana, Agback, Peter, Achour, Adnane, Qu, Xiaobo, Orekhov, Vladislav
Nuclear magnetic resonance (NMR) spectroscopy has become a formidable tool for biochemistry and medicine. Although J-coupling carries essential structural information it may also limit the spectral resolution. Homonuclear decoupling remains a challen
Externí odkaz:
http://arxiv.org/abs/2212.01144
Autor:
Jahangiri, Amir, Han, Xiao, Lesovoy, Dmitry, Agback, Tatiana, Agback, Peter, Achour, Adnane, Orekhov, Vladislav
A new deep neural network based on the WaveNet architecture (WNN) is presented, which is designed to grasp specific patterns in the NMR spectra. When trained at a fixed non-uniform sampling (NUS) schedule, the WNN benefits from pattern recognition of
Externí odkaz:
http://arxiv.org/abs/2208.02552
Autor:
Tatiana Agback, Dmitry Lesovoy, Xiao Han, Alexander Lomzov, Renhua Sun, Tatyana Sandalova, Vladislav Yu. Orekhov, Adnane Achour, Peter Agback
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The dengue protease NS2B/NS3pro has been reported to adopt either an ‘open’ or a ‘closed’ conformation. We have developed a conformational filter that combines NMR with MD simulations to identify conformational ensembles that dominat
Externí odkaz:
https://doaj.org/article/0d1dcdf25f9d4b78ade9adb69f7c9149
Akademický článek
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Akademický článek
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Autor:
Wang, Zi, Guo, Di, Tu, Zhangren, Huang, Yihui, Zhou, Yirong, Wang, Jian, Feng, Liubin, Lin, Donghai, You, Yongfu, Agback, Tatiana, Orekhov, Vladislav, Qu, Xiaobo
The non-uniform sampling is a powerful approach to enable fast acquisition but requires sophisticated reconstruction algorithms. Faithful reconstruction from partial sampled exponentials is highly expected in general signal processing and many applic
Externí odkaz:
http://arxiv.org/abs/2012.14830
Autor:
Qu, Xiaobo, Huang, Yihui, Lu, Hengfa, Qiu, Tianyu, Guo, Di, Agback, Tatiana, Orekhov, Vladislav, Chen, Zhong
Nuclear magnetic resonance (NMR) spectroscopy serves as an indispensable tool in chemistry and biology but often suffers from long experimental time. We present a proof-of-concept of application of deep learning and neural network for high-quality, r
Externí odkaz:
http://arxiv.org/abs/1904.05168
Akademický článek
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Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Detailed structural knowledge of enzyme-inhibitor complexes trapped in intermediate state is the key for a fundamental understanding of reaction mechanisms taking place in enzymes and is indispensable as a structure-guided drug de
Externí odkaz:
https://doaj.org/article/cd2f2af7a0814709812ab5bea8083cb8